Patents by Inventor Xiufang Zheng

Xiufang Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-substituted 5-amino-6H-thiazolo[4,5-D]pyrimidine-2,7-dione compounds for the treatment and prophylaxis of virus infection
    Patent number: 9441008
    Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: September 13, 2016
    Assignee: Hoffmann-LA Roche Inc.
    Inventors: Dongdong Chen, Song Feng, Lu Gao, Chao Li, Baoxia Wang, Lisha Wang, Hongying Yun, Xiufang Zheng
  • NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION
    Publication number: 20160229853
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, W and X are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: April 8, 2016
    Publication date: August 11, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Lu GAO, Lei GUO, Chungen LIANG, Baoxia WANG, Lisha WANG, Hongying YUN, Weixing ZHANG, Xiufang ZHENG
  • NOVEL 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2,7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION
    Publication number: 20160194350
    Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: December 3, 2015
    Publication date: July 7, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Dongdong Chen, Song Feng, Lu Gao, Chao Li, Baoxia Wang, Lisha Wang, Hongying Yun, Xiufang Zheng
  • NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION
    Publication number: 20160159794
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5, W and X are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: February 11, 2016
    Publication date: June 9, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Lisha Wang, Hongying Yun, Weixing Zhang, Xiufang Zheng
  • NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION
    Publication number: 20160068531
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5, R6, W1, W2, W3, A and X are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: November 16, 2015
    Publication date: March 10, 2016
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Lisha WANG, Lu GAO, Mengwei HUANG, Lei GUO, Chungen LIANG, Wei ZHU, Song FENG, Xiufang ZHENG, Weixing ZHANG, Guolong WU, Baoxia WANG, Hongying YUN
  • Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease
    Patent number: 8871756
    Abstract: A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R10, A, Q, X and Y are as defined in the specification and claims, and their use as a pharmaceutical for the treatment or prophylaxis of respiratory syncytial virus disease.
    Type: Grant
    Filed: July 30, 2012
    Date of Patent: October 28, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Li Chen, Lichun Feng, Song Feng, Lu Gao, Tao Guo, Mengwei Huang, Chungen Liang, Yongfu Liu, Lisha Wang, Jason Christopher Wong, Jim Zhen Wu, Xihan Wu, Hongying Yun, Xiufang Zheng
  • Compounds for the treatment and prophylaxis of respiratory syncytial virus disease
    Patent number: 8604019
    Abstract: The invention relates to the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2 and X are as defined in the description and claims, which are useful for the treatment or prophylaxis of RSV infection.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: December 10, 2013
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Chungen Liang, Lisha Wang, Hongying Yun, Xiufang Zheng
  • COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE
    Publication number: 20130196974
    Abstract: A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R10, A, Q, X and Y are as defined in the specification and claims, and their use as a pharmaceutical for the treatment or prophylaxis of respiratory syncytial virus disease.
    Type: Application
    Filed: July 30, 2012
    Publication date: August 1, 2013
    Inventors: Li Chen, Lichun Feng, Song Feng, Lu Gao, Tao Guo, Mengwei Huang, Chungen Liang, Yongfu Liu, Lisha Wang, Jason Christopher Wong, Jim Zhen Wu, Xihan Wu, Hongying Yun, Xiufang Zheng