Abstract: Disclosed are a high-strength multiphase steel tinned raw plate and a manufacturing method therefor, wherein the mass percentages of the components of the multiphase steel tinned raw plate are: 0.081%-0.14% of C, 0.2%-0.8% of Mn, 0.01%-0.09% of Al, 0.01%-0.03% of P, 0.002%-0.015% of N, also containing one or more than one of 0.001%-0.005% of B, 0.005%-0.05% of Cr, 0.001%-0.1% of Ti, 0.001%-0.2% of Nb, 0.005%-0.03% of Cu, 0.001%-0.008% of Mo, and the balance of Fe and other inevitable impurities; and satisfy: 0.21%?Mn+1.3 Cr+3.2 Mo+0.5 Cu?0.91%. The tinned raw plate has a structure comprising ferrite grains, pearlite, martensite and cementite particles, wherein the total volume fraction of the pearlite, martensite and cementite particles is 5%-20%, the volume fraction of the martensite is 1%-5%, and the martensite has a solid solution content of carbon of ?0.07%.

Abstract: This document relates to machine learning. One example includes a method or technique that can be performed on a computing device. The method or technique can include obtaining a task-semantically-conditioned generative model that has been pretrained based at least on a first training data set having unlabeled training examples and semantically conditioned based at least on a second training data set having dialog act-labeled utterances. The method or technique can also include inputting dialog acts into the semantically-conditioned generative model and obtaining synthetic utterances that are output by the semantically-conditioned generative model. The method or technique can also include outputting the synthetic utterances.

Abstract: A biosensing system configured to detect a target DNA and methods of detecting a target DNS are presented. The biosensing system comprises a biosensor comprising a suspension of a hybridization buffer containing dispersed gold nanoparticles, sodium chloride, and single-stranded DNA probes configured to undergo DNA hybridization with the target DNA.

Abstract: A point-of-care testing (POCT) quantitative pathogen detection device is provided, without the aid of any detectors. In an illustrative embodiment, a POCT pathogen detection device includes an inlet microwell for receiving a substance, the inlet microwell connected to a distribution channel to distribute the substance to an analyzing component. The device also includes an analyzing component. that includes a first pathogen detection component. The first pathogen detection component includes a platinum nanoparticle-labeled DNA-probe configured to propel a dye through a bar-chart channel when a pathogen in the substance reacts platinum nanoparticle-labeled DNA-probe. The platinum nanoparticle-labeled DNA-probe is configured to react with a first pathogen. The device also includes at least one magnet configured to keep unreacted platinum nanoparticle-labeled DNA-probe in a sample recognition microwell, thereby inhibiting propulsion of the dye into the bar-chart channel when the pathogen is not detected.

Abstract: This document relates to machine learning. One example includes a method or technique that can be performed on a computing device. The method or technique can include obtaining a task-adapted generative model that has been tuned using one or more task-specific seed examples. The method or technique can also include inputting dialog acts into the task-adapted generative model and obtaining synthetic utterances that are output by the task-adapted generative model. The method or technique can also include populating a synthetic training corpus with synthetic training examples that include the synthetic utterances. The synthetic training corpus may be suitable for training a natural language understanding model.

Abstract: This document relates to machine learning. One example includes a method or technique that can be performed on a computing device. The method or technique can include obtaining a task-adapted generative model that has been tuned using one or more task-specific seed examples. The method or technique can also include inputting dialog acts into the task-adapted generative model and obtaining synthetic utterances that are output by the task-adapted generative model. The method or technique can also include populating a synthetic training corpus with synthetic training examples that include the synthetic utterances. The synthetic training corpus may be suitable for training a natural language understanding model.

Abstract: A method of synthesizing a smart paper transformer is provided. The method comprises combining paper with HAuCl4 and stirring together in an aqueous solution to form a pulp. The pulp is treated with NaBH4 aqueous solution. The treated pulp is then washed and centrifuged with water a number of times to form a gold nanosponge (AuNS) catalyst pulp.

Abstract: A composition includes a photon upconversion nanoparticle coupled to a photosensitizer nanoparticle that can absorb light and convert tissue oxygen into reactive oxygen species. A low temperature hydrothermal method of making photon upconversion nanoparticles includes dispersing Yb(NO3)3, Y(NO3)3, and Er(NO3)3 in water to prepare a mixture; adding an ethylenediaminetetraacetic acid and NaF with sonication to make a solution; adjusting a pH of the solution to approximately 3.5 using HNO3 and NaOH; treating the solution hydrothermally at approximately 130° C. for approximately 4 hours; quenching to approximately 20° C.; collecting and washing the photon upconversion nanoparticles.

Abstract: A low-cost photothermal biosensing method and apparatus for the quantitative genetic detection of pathogens such as MTB DNA on a paper hybrid device using a thermometer. First, DNA capture probes were simply immobilized on paper through a one-step surface modification process. After DNA sandwich hybridization, oligonucleotide-functionalized gold nanoparticles (AuNPs) were introduced on paper and then catalyzed the oxidation reaction of 3,3?,5,5?-tetramethylbenzidine (TMB). The produced oxidized TMB, acting as a strong photothermal agent, was used for the photothermal biosensing of MTB DNA under 808 nm laser irradiation. Under optimal conditions, the on-chip quantitative detection of the target DNA was readily achieved using an inexpensive thermometer as a signal recorder. Illustrative embodiments do not require any expensive analytical instrumentation, but can achieve higher sensitivity and there are no color interference issues, compared to conventional colorimetric methods.

Abstract: This document relates to machine learning. One example includes a method or technique that can be performed on a computing device. The method or technique can include obtaining a task-adapted generative model that has been tuned using one or more task-specific seed examples. The method or technique can also include inputting dialog acts into the task-adapted generative model and obtaining synthetic utterances that are output by the task-adapted generative model. The method or technique can also include populating a synthetic training corpus with synthetic training examples that include the synthetic utterances. The synthetic training corpus may be suitable for training a natural language understanding model.

Abstract: A blended polyester laminating film resistant to discoloration caused by cooking, comprising polyethylene terephthalate and polybutylene terephthalate. The blended polyester laminating film comprises three layers, i.e., upper, middle, and lower layers. One surface layer contains SiO2 in a mass fraction of 1200-2000 ppm added by in-situ polymerization. The blended polyester laminating film is manufactured by a three-layer coextrusion biaxial stretching method, and the manufacturing method is 240-275° C. A film-laminated metal sheet manufactured from the blended polyester laminating film has excellent resistance to discoloration caused by cooking, and is applied to metal containers for food and beverage packaging that require high-temperature sterilization.

Abstract: A processing unit can operate a first recurrent computational model (RCM) to provide first state information and a predicted result value. The processing unit can operating a first network computational model (NCM) to provide respective expectation values of a plurality of actions based at least in part on the first state information. The processing unit can provide an indication of at least one of the plurality of actions, and receive a reference result value, e.g., via a communications interface. The processing unit can train the first RCM based at least in part on the predicted result value and the reference result value to provide a second RCM, and can train the first NCM based at least in part on the first state information and the at least one of the plurality of actions to provide a second NCM.

Abstract: Embodiments described herein are related to a one-step surface modification method with 3-aminopropyl trimethoxysilane (APTMS), which was developed and applied for DNA immobilization on a paper-based device via the ionic adsorption.

Abstract: A biosensing system configured to detect a target DNA and methods of detecting a target DNS are presented. The biosensing system comprises a biosensor comprising a suspension of a hybridization buffer containing dispersed gold nanoparticles, sodium chloride, and single-stranded DNA probes configured to undergo DNA hybridization with the target DNA.

Abstract: A type of microfluidic platform, photothermal bar-chart chip (PT-Chip), uses on-chip nanomaterial-mediated photothermal effect as a tunable microfluidic driving force to drive ink bar-charts in a visual quantitative readout fashion. The photothermal bar-chart pumping performance can be adjusted remotely by tuning the irradiation parameters, without the need to change any on-chip parameters. The PT-Chip enables a POC visual quantitative diagnostics, by forming nanomaterial-mediated photothermal effects-driven bar-chart microchip for visual quantitative immuno-sensing. In this immunoassay, biomolecules are visually quantified by directly reading the distance that fluids move on the PT-Chip.

Abstract: Certain embodiments are directed to a paper hybrid microfluidic microplate. In certain aspects, the hybrid microfluidic microplate is a low-cost, sensitive, and fast diagnostic apparatus for detecting pathogens, diagnosing disease and other bio-applications, especially for low-resource settings.

Abstract: Certain embodiments are directed to an ultrasensitive poly(methyl methacrylate) (PMMA) ELISA microfluidic microplate, where the protein is covalently bound to a poly-lysine modified or carboxylated PMMA surface.

Abstract: Certain embodiments are directed to paper and its hybrid microfluidic devices integrated with nucleic acid amplification for simple, cost-effective, rapid, and sensitive pathogen detection, especially in low-resource settings.

Abstract: Disclosed are a high-strength multiphase steel tinned raw plate and a manufacturing method therefor, wherein the mass percentages of the components of the multiphase steel tinned raw plate are: 0.081%-0.14% of C, 0.2%-0.8% of Mn, 0.01%-0.09% of Al, 0.01%-0.03% of P, 0.002%-0.015% of N, also containing one or more than one of 0.001%-0.005% of B, 0.005%-0.05% of Cr, 0.001%-0.1% of Ti, 0.001%-0.2% of Nb, 0.005%-0.03% of Cu, 0.001%-0.008% of Mo, and the balance of Fe and other inevitable impurities; and satisfy: 0.21% <Mn+1.3 Cr+3.2 Mo+0.5 Cu <0.91%. The tinned raw plate has a structure comprising ferrite grains, pearlite, martensite and cementite particles, wherein the total volume fraction of the pearlite, martensite and cementite particles is 5%-20%, the volume fraction of the martensite is 1%-5%, and the martensite has a solid solution content of carbon of ?0.07%.

Abstract: A method of synthesizing a smart paper transformer is provided. The method comprises combining paper with HAuCl4 and stirring together in an aqueous solution to form a pulp. The pulp is treated with NaBH4 aqueous solution. The treated pulp is then washed and centrifuged with water a number of times to form a gold nanosponge (AuNS) catalyst pulp.