Patents by Inventor Xiulei Mo

Xiulei Mo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMAD4 Complex Inducers and Uses in Cancer Therapy
    Publication number: 20230201173
    Abstract: In certain embodiments, this disclosure relates to methods of identifying cancer agents and treating cancer with identified agents. In certain embodiments, the caner agents are capable of inducing or stabilizing SMAD4 oligomerization.
    Type: Application
    Filed: December 13, 2022
    Publication date: June 29, 2023
    Inventors: Haian Fu, Xiulei Mo, Cong Tang
  • KRAS G12V Mutant Binds to JAK1, Inhibitors, Pharmaceutical Compositions, and Methods Related Thereto
    Publication number: 20220306688
    Abstract: This disclosure relates to the discovery that a G12V mutant of KRAS (hereinafter KRAS G12V) binds to JAK1, i.e., the existence of a KRAS G12V and JAK1 binding interaction. In certain embodiments, this disclosure relates to methods of disrupting the KRAS G12V and JAK1 interaction reversing KRAS G12V induced immune escape by cancer cells utilizing agents that prevent the binding of JAK1 to KRAS G12V.
    Type: Application
    Filed: June 8, 2020
    Publication date: September 29, 2022
    Inventors: Haian Fu, Xiulei Mo, Cong Tang