Patents by Inventor Xiuling Xu

Xiuling Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pegylated cyclopamine analogue, preparation method and uses thereof
    Patent number: 8877928
    Abstract: A PEGylated cyclopamine analog, preparation method, uses thereof and methods for treating proliferative diseases using the same are disclosed. The PEGylated cyclopamine analog is a compound represented by the following formula I, a compound comprising at least one group represented by the following formula I (in formula I, R is straight or branched polyethylene glycol having a molecular weight between 200 and 200,000 Dalton, L and X are linking groups), or their single enantiomers, mixture of enantiomers, mixture of diastereomers, pharmaceutically acceptable salts, solvates, or hydrates.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: November 4, 2014
    Assignee: Shandong University
    Inventors: Chun Song, Chengzhi Zhang, Xin Zhao, Zhao Hu, Xiuling Xu, Youzhong Zhang, Mingyi Wang, Zhijun Sun
  • PEGYLATED CYCLOPAMINE ANALOGUE, PREPARATION METHOD AND USES THEREOF
    Publication number: 20130324569
    Abstract: A PEGylated cyclopamine analog, preparation method, uses thereof and methods for treating proliferative diseases using the same are disclosed. The PEGylated cyclopamine analog is a compound represented by the following formula I, a compound comprising at least one group represented by the following formula I (in formula I, R is straight or branched polyethylene glycol having a molecular weight between 200 and 200,000 Dalton, L and X are linking groups), or their single enantiomers, mixture of enantiomers, mixture of diastereomers, pharmaceutically acceptable salts, solvates, or hydrates.
    Type: Application
    Filed: February 25, 2011
    Publication date: December 5, 2013
    Applicant: Beijing Kemedicine Co., Ltd.
    Inventors: Chun Song, Chengzhi Zhang, Xin Zhao, Zhao Hu, Xiuling Xu, Youzhong Zhang, Mingyi Wang, Zhijun Sun
  • Active cell culture via shape memory
    Patent number: 8404484
    Abstract: Substrates for cell culture and tissue engineering bioreactors consisting of polymers that change their shape over time under stimulation by temperature change, hydration, degradation, or other means. A method of controlling cell culture using a biodegradable shape memory polymer, wherein shape changes can transfer stresses, strains, or both to adherent or otherwise connected cells such that the mechanical stimulus impacts cell development and the resulting properties of tissues.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: March 26, 2013
    Assignee: Syracuse University
    Inventors: Patrick Mather, James Henderson, Kelly Burke, Kevin Davis, Xiuling Xu
  • Active Cell Culture Via Shape Memory
    Publication number: 20110059527
    Abstract: Substrates for cell culture and tissue engineering bioreactors consisting of polymers that change their shape over time under stimulation by temperature change, hydration, degradation, or other means. A method of controlling cell culture using a biodegradable shape memory polymer, wherein shape changes can transfer stresses, strains, or both to adherent or otherwise connected cells such that the mechanical stimulus impacts cell development and the resulting properties of tissues.
    Type: Application
    Filed: July 15, 2010
    Publication date: March 10, 2011
    Applicant: SYRACUSE UNIVERSITY
    Inventors: Patrick Mather, James Henderson, Kelly Burke, Kevin Davis, Xiuling Xu