Abstract: A fully variable electro-hydraulic valve system, comprising a sliding sleeve (A103, B103), a spiral shaft (A102, B102), a piston (A105, B105), and a reset spring (A104, B104). The sliding sleeve (A103, B103) is fixed relative to an engine; the piston (A105, B105) abuts against a valve assembly (106); the spiral shaft (A102, B102) is axially controlled by a cam surface of a camshaft (101); and the spiral shaft (A102, B102) is provided with a spiral groove (A102D, B102D) and a blockage part (A102G, B102G). When the spiral groove (A102D, B102D) communicates with a limiting oil hole (A118, B118), a sliding sleeve cavity (Q) communicates with a low-pressure oil path of the engine for pressure relief.

Abstract: A fully variable electro-hydraulic valve system having a buffering function, comprising: a camshaft (101), a valve assembly (106), a sliding sleeve (103), a spiral shaft (102), a piston (105), and a position restoring spring (104). The sliding sleeve (103) is fixed relative to an engine, the piston (105) abuts against the valve assembly (106), and the spiral shaft (102) is controlled by a cam surface of the camshaft (101) in the axial direction. sliding sleeve (103) is provided with a buffering oil hole (123) that communicates with a buffering cavity (R) and with a low-pressure oil circuit of the engine by means of a throttling device (124). When a valve is going to be seated, the piston collides with a buffering ring (121), and due to the effect of the throttling device, engine oil within the buffering cavity has a damping effect on the movement of the buffering ring.

Abstract: A compression release engine in-cylinder braking system, comprising a valve mechanism, an oil cylinder device, an oil pump device, and an oil supply device. The oil cylinder device and the oil pump device of each air cylinder communicate with each other through a pressure transmission oil circuit, which communicates with the oil supply device through a low-pressure relief valve. An air release valve is arranged at the high end of an oil circuit system. During in-cylinder braking, the air release valve is closed, an electromagnetic reversing valve is energized, engine oil having a pressure of P1 is supplied to the pressure transmission oil circuit, and a cam abuts against and pushes the oil pump device to pump high-pressure oil to the oil cylinder device, so as to push a rocker arm to open a valve, thereby achieving in-cylinder braking.

Abstract: A compression release engine in-cylinder braking system, comprising a valve mechanism (I), an oil cylinder device (III), an oil pump device (II), and an oil supply device (IV). The oil cylinder device (III) and the oil pump device (II) of each air cylinder communicate with each other through a pressure transmission oil circuit (L). The pressure transmission oil circuit (L) communicates with the oil supply device (IV) through a low-pressure relief valve (90). An air release valve (200) is arranged at the high end of an oil circuit system. During in-cylinder braking, the air release valve (200) is closed, an electromagnetic reversing valve (80) is energized, engine oil having a pressure of P1 is supplied to the pressure transmission oil circuit (L), and a cam (16) abuts against and pushes the oil pump device (II) to pump high-pressure oil to the oil cylinder device (III), so as to push a rocker arm (12) to open a valve (10), thereby achieving in-cylinder braking.

Abstract: A fully variable electro-hydraulic valve system, comprising a sliding sleeve (A103, B103), a spiral shaft (A102, B102), a piston (A105, B105), and a reset spring (A104, B104); the sliding sleeve (A103, B103) is fixed relative to an engine; the piston (A105, B105) abuts against a valve assembly (106); the spiral shaft (A102, B102) is axially controlled by a cam surface of a camshaft (101); and the spiral shaft (A102, B102) is provided with a spiral groove (A102D, B102D) and a blockage part (A102G, B102G).

Abstract: A fully variable electro-hydraulic valve system having a buffering function, comprising: a camshaft (101), a valve assembly (106), a sliding sleeve (103), a spiral shaft (102), a piston (105), and a position restoring spring (104); the sliding sleeve (103) is fixed relative to an engine; the piston (105) abuts against the valve assembly (106); the spiral shaft (102) is controlled by a cam surface of the camshaft (101) in the axial direction; a spiral surface (102E) is provided at a first end of the spiral shaft (102), and a control gear (102A) is provided at a second end thereof; the sliding sleeve (103) is provided with a buffering oil hole (123) that communicates with a buffering cavity (R), and the buffering oil hole (123) communicates with a low-pressure oil circuit of the engine by means of a throttling device (124).

Abstract: Provided herein are methods for the diagnosis, staging, prognosis, or management of liver disease, e.g. chronic liver disease, and other diseases using profiles of the ubiquitin-proteasome system determined from acellular body fluids or cell-containing samples. Further provided are methods of predicting response to therapy in certain populations of patients with liver disease.

Abstract: Provided herein are methods for the diagnosis, prognosis, or management of neoplastic diseases, i.e. cancer, and other diseases using profiles of the ubiquitin-proteasome system determined from acellular body fluids or cell-containing samples. Further provided are methods of predicting response to therapy in certain populations of cancer patients.

Abstract: Provided herein are methods for the diagnosis, prognosis, or management of neoplastic diseases, i.e. cancer, and other diseases using profiles of the ubiquitin-protcasome system determined from acellular body fluids or cell-containing samples. Further provided are methods of predicting response to therapy in certain populations of cancer patients.