Abstract: Compounds of general Formula I, II, III, IV, V and their pharmaceutically acceptable salts, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are synthesis, compositions, and uses of such compounds.

Abstract: A housing, a vibration assembly, and a vehicle including the vibration assembly is provided, wherein the housing includes a polymer layer and a metal layer. The metal layer is located at an innermost layer of the housing. A material used for the metal layer includes a metal material. The polymer layer is located on an outer side of the metal layer. A material used for the polymer layer includes a polymer material. The housing can convert mechanical vibration energy into heat energy for dissipation, thereby achieving a noise reduction effect.

Abstract: The present application relates to a wheel finishing device, which includes a lower brush system, upper rim brush systems, a riser brush system, a valve hole brush system and the like. The device can be used for removing burrs from an upper rim, a center hole, a flange drainage channel, a riser and a valve hole of a wheel, and simultaneously has the characteristics of high automation degree, high removal efficiency, advanced process, strong generality and high safety and stability.

Abstract: Disclosed is an improved wheel end face detection and correction device, which includes a detection and correction system, a synchronous clamping system, an expansion and rotating system, compression and positioning systems, a lifting system and the like. The device may be used for detecting the end face run-out of the flange of a wheel and implementing on-line correction, and has the characteristics of high automation degree, advanced process, strong universality and safe and stable performance at the same time.

Abstract: Disclosed is a comprehensive thread checking fixture, includes a no-go end, a handle, a measuring column, a measuring sleeve and a jackscrew. The checking fixture not only can be used for detecting the size of the detected threads, but also can be used for detecting the depth of the detected threads, and has the characteristics of simple structure, high detection precision, strong compatibility, low manufacturing cost and the like at the same time.

Abstract: Disclosed is a comprehensive thread checking fixture, includes a no-go end, a handle, a measuring column, a measuring sleeve and a jackscrew. The checking fixture not only can be used for detecting the size of the detected threads, but also can be used for detecting the depth of the detected threads, and has the characteristics of simple structure, high detection precision, strong compatibility, low manufacturing cost and the like at the same time.

Abstract: Disclosed is an improved wheel end face detection and correction device, which includes a detection and correction system, a synchronous clamping system, an expansion and rotating system, compression and positioning systems, a lifting system and the like. The device may be used for detecting the end face run-out of the flange of a wheel and implementing on-line correction, and has the characteristics of high automation degree, advanced process, strong universality and safe and stable performance at the same time.

Abstract: The present application relates to a wheel finishing device, which includes a lower brush system, upper rim brush systems, a riser brush system, a valve hole brush system and the like. The device can be used for removing burrs from an upper rim, a center hole, a flange drainage channel, a riser and a valve hole of a wheel, and simultaneously has the characteristics of high automation degree, high removal efficiency, advanced process, strong generality and high safety and stability.

Abstract: The present invention discloses a fixture, which is composed of a base plate, a support column, a profiling positioning block, support rods, positioning sleeves and the like. When in use, the fixture provided by the present invention can meet the requirement for performing three-coordinates measuring on a blank and a finished product subjected to machining for a steering knuckle workpiece, and simultaneously has the characteristics of simple structure, low manufacturing cost, convenient use and the like.

Abstract: The present invention discloses a fixture, which is composed of a base plate, a support column, a profiling positioning block, support rods, positioning sleeves and the like. When in use, the fixture provided by the present invention can meet the requirement for performing three-coordinates measuring on a blank and a finished product subjected to machining for a steering knuckle workpiece, and simultaneously has the characteristics of simple structure, low manufacturing cost, convenient use and the like.