Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.

Abstract: The presently disclosed subject matter provides methods for improving production of cells comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a TCR like fusion molecule). The methods disclosed herein can improve the activity and/or efficiency of the cells.

Abstract: A process for end-capping a dimethylsilanol terminated polydiorganosiloxane with one or more di, tri and/or tetra alkoxysilanes in the presence of a basic end-capping catalyst starting material is provided. An acidic stabilizing/neutralising agent is subsequently added. The acidic stabilizing/neutralising agent is selected from one or more fatty acids having from 8 to 26 carbons; an alkane sulphonic acid having from 1 to 10 carbons; acidic fumed silica and/or one or more acidic liquid polybutadienes or a mixture thereof. The resulting capped polymeric material may be utilized as a polymer in, e.g., an organopolysiloxane elastomer composition.

Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.

Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.

Abstract: This disclosure relates to a one-part condensation curable silicone sealant composition suitable for use as a construction sealant for silicone structural glazing (SSG) applications, in particular for use in curtain wall façade systems. The one-part condensation curable silicone sealant composition contains an alkoxylated MQ silicone resin, optionally in the presence of a polysiloxane carrier fluid. When the one-part condensation curable silicone sealant composition is cured, the resulting sealant is designed to maintain adhesive integrity and to be stable in extreme climates, particularly at high temperatures.

Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.

Abstract: A process for end capping and chain extending silanol terminated polydiorganosiloxanes with a mixture of one or more alkylacetoxydialkoxysilanes and one or more alkyldiacetoxyalkoxysilanes. The resulting capped polymeric material may be utilised as a polymer in e.g. a one-part alkoxy sealant composition such as, for example, an alkoxy low modulus clean (non-staining) or clear sealant composition.

Abstract: This disclosure relates to a process for the preparation of a one component translucent room temperature vulcanisable (RTV) silicone composition. The RTV composition comprises chain-extended alkoxy end-capped polydiorganosiloxane polymers, and tin-based catalysts. The process generates a one component translucent RTV silicone composition which is stable in storage, in the absence of moisture, and is curable in the presence of atmospheric moisture at ambient temperature. The one component translucent RTV silicone composition resulting from the process was unexpectedly found to have excellent adhesive properties towards polyvinyl chloride (PVC) substrates.

Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.

Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.

Abstract: The presently disclosed subject matter provides for expression cassettes that allow for expression of a globin gene or a functional portion thereof, vectors comprising thereof, and cells transduced with such expression cassettes and vectors. The presently disclosed subject matter further provides methods for treating a hemoglobinopathy in a subject comprising administering an effective amount of such transduced cells to the subject.

Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.

Abstract: A process for end-capping a dimethylsilanol terminated polydiorganosiloxane with one or more di, tri and/or tetra alkoxysilanes in the presence of a basic end-capping catalyst starting material is provided. An acidic stabilizing/neutralising agent is subsequently added. The acidic stabilizing/neutralising agent is selected from one or more fatty acids having from 8 to 26 carbons; an alkane sulphonic acid having from 1 to 10 carbons; acidic fumed silica and/or one or more acidic liquid polybutadienes or a mixture thereof. The resulting capped polymeric material may be utilized as a polymer in, e.g., an organopolysiloxane elastomer composition.

Abstract: The presently disclosed subject matter provides for expression cassettes that allow for expression of a globin gene or a functional portion thereof, vectors comprising thereof, and cells transduced with such expression cassettes and vectors. The presently disclosed subject matter further provides methods for treating a hemoglobinopathy in a subject comprising administering an effective amount of such transduced cells to the subject.

Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.

Abstract: A one-part low modulus room temperature vulcanisable (RTV) silicone composition containing a catalyst comprising (i) a titanate and/or zirconate and (ii) a metal carboxylate salt which cures to a low modulus silicone elastomer which may be used as a non-staining (clean) sealant having high movement capability.

Abstract: A process for end capping and chain extending silanol terminated polydiorganosiloxanes with a mixture of one or more alkylacetoxydialkoxysilanes and one or more alkyldiacetoxyalkoxysilanes. The resulting capped polymeric material may be utilised as a polymer in e.g. a one-part alkoxy sealant composition such as, for example, an alkoxy low modulus clean (non-staining) or clear sealant composition.

Abstract: A light emitting apparatus affording high quality colors and energy economy and an electronic device comprising the light emitting apparatus.

Abstract: Provided herein are anti-CD20 antibodies and uses thereof for treatment and diagnosis. Also provided are CD20 antigens for the production of anti-CD20 antibodies and methods of generating anti-CD20 antibodies using the CD20 antigens.