Patents by Inventor Xiuyan YANG

Xiuyan YANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound used as SIRT6 small-molecule allosteric activator and pharmaceutical composition thereof
    Patent number: 12098119
    Abstract: Disclosed by the present invention are an SIRT6 small-molecule allosteric activator and the application thereof and provided is an SIRT6 small-molecule allosteric activator that contains a derivative as shown in formula (1) or a pharmacologically acceptable salt thereof as the active ingredient. The SIRT6 small-molecule allosteric activator designed and synthesized in the present invention has high efficacy and low toxicity, may significantly activate SIRT6 activity during in vitro experiments, and has great importance in the development of pharmaceuticals for relevant diseases.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: September 24, 2024
    Assignee: Nutshell BioTech (Shanghai) Co., Ltd.
    Inventors: Jian Zhang, Yinyi Chen, Cong Ruan, Xiuyan Yang, Chengxiang Wang, Qiufen Zhang, Jialin Shang, Xinyuan Xu
  • COMPOUND USED AS SIRT6 SMALL-MOLECULE ALLOSTERIC ACTIVATOR AND PHARMACEUTICAL COMPOSITION THEREOF
    Publication number: 20220220069
    Abstract: Disclosed by the present invention are an SIRT6 small-molecule allosteric activator and the application thereof and provided is an SIRT6 small-molecule allosteric activator that contains a derivative as shown in formula (1) or a pharmacologically acceptable salt thereof as the active ingredient. The SIRT6 small-molecule allosteric activator designed and synthesized in the present invention has high efficacy and low toxicity, may significantly activate SIRT6 activity during in vitro experiments, and has great importance in the development of pharmaceuticals for relevant diseases.
    Type: Application
    Filed: May 14, 2018
    Publication date: July 14, 2022
    Applicant: SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Jian ZHANG, Yinyi CHEN, Cong RUAN, Xiuyan YANG, Chengxiang WANG, Qiufen ZHANG, Jialin SHANG, Xinyuan XU