Patents by Inventor Xiuzhi S. Sun

Xiuzhi S. Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11135163
    Abstract: Peptide hydrogels having a self-assembling, 3-dimensional nanofiber matrix are described. The nanofiber matrix comprises an amphiphilic peptide and optionally albumin. The peptide comprises (consists of) a terminal hydrophobic region, a central turning region, and a terminal hydrophilic region. Methods of making such hydrogels are also described, along with methods of using the hydrogels as scaffolding for tissue engineering, hemostatic agents, as well as 3-dimensional cell cultures, and for drug delivery, encapsulation of active agents (therapeutic cells, molecules, drugs, compounds), cell transplantation, cell storage, virus culture and storage.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: October 5, 2021
    Assignee: Kansas State University Research Foundation
    Inventors: Xiuzhi S. Sun, Hongzhou Huang, Tiffany L. Carter, Mark L. Weiss
  • Publication number: 20180353428
    Abstract: Peptide hydrogels having a self-assembling, 3-dimensional nanofiber matrix are described. The nanofiber matrix comprises an amphiphilic peptide and optionally albumin. The peptide comprises (consists of) a terminal hydrophobic region, a central turning region, and a terminal hydrophilic region. Methods of making such hydrogels are also described, along with methods of using the hydrogels as scaffolding for tissue engineering, hemostatic agents, as well as 3-dimensional cell cultures, and for drug delivery, encapsulation of active agents (therapeutic cells, molecules, drugs, compounds), cell transplantation, cell storage, virus culture and storage.
    Type: Application
    Filed: August 22, 2018
    Publication date: December 13, 2018
    Inventors: Xiuzhi S. Sun, Hongzhou Huang, Tiffany L. Carter
  • Publication number: 20170189334
    Abstract: Peptide hydrogels having a self-assembling, 3-dimensional nanofiber matrix are described. The nanofiber matrix comprises an amphiphilic peptide and optionally albumin. The peptide comprises (consists of) a terminal hydrophobic region, a central turning region, and a terminal hydrophilic region. Methods of making such hydrogels are also described, along with methods of using the hydrogels as scaffolding for tissue engineering, hemostatic agents, as well as 3-dimensional cell cultures, and for drug delivery, encapsulation of active agents (therapeutic cells, molecules, drugs, compounds), cell transplantation, cell storage, virus culture and storage.
    Type: Application
    Filed: June 5, 2015
    Publication date: July 6, 2017
    Inventors: Xiuzhi S. Sun, Hongzhou Huang, Tiffany L. Carter
  • Publication number: 20160030629
    Abstract: Peptide-albumin hydrogels having a self-assembling, 3-dimensional nanofiber matrix are described. The nanofiber matrix comprises an amphiphilic peptide and albumin. The peptide comprises a terminal hydrophobic region, a central turning region, and a terminal hydrophilic region. Methods of making such hydrogels are also described, along with methods of using the hydrogels as scaffolding for tissue engineering, as 3-dimensional cell cultures, and for drug delivery, encapsulation of active agents (therapeutic cells, molecules, drugs, compounds), cell transplantation, cell storage, virus culture and storage.
    Type: Application
    Filed: December 6, 2013
    Publication date: February 4, 2016
    Inventors: Xiuzhi S. Sun, Hongzhou Huang, Thu Annelise Nguyen
  • Patent number: 6716022
    Abstract: Molding apparatus (10) is provided which allows use of a particulate non-liquid molding material (121) to produce a variety of articles, such as frustoconical barrel segments (122). The apparatus (10) includes a female mold segment (18) including generally annular inner and outer sidewalls (70, 76) and a complemental male mold section (20) having an annular sidewall unit (30). In use, a molding material (121) is placed between the sidewalls (70, 76) and the section (20) is shifted so that it telescopes within the section (18); this compresses the material (121) to a desired final shape, which is then hardened to yield the final product (122). An optional wear insert (26) can be used with female mold section (18), which can be replaced as needed and assists in cleaning of the apparatus (10).
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: April 6, 2004
    Assignee: Kansas State University Research Foundation
    Inventors: Xiuzhi S. Sun, Greggory S. Karr
  • Publication number: 20030185928
    Abstract: Molding apparatus (10) is provided which allows use of a particulate non-liquid molding material (121) to produce a variety of articles, such as frustoconical barrel segments (122). The apparatus (10) includes a female mold segment (18) including generally annular inner and outer sidewalls (70, 76) and a complemental male mold section (20) having an annular sidewall unit (30). In use, a molding material (121) is placed between the sidewalls (70, 76) and the section (20) is shifted so that it telescopes within the section (18); this compresses the material (121) to a desired final shape, which is then hardened to yield the final product (122). An optional wear insert (26) can be used with female mold section (18), which can be replaced as needed and assists in cleaning of the apparatus (10).
    Type: Application
    Filed: March 24, 2003
    Publication date: October 2, 2003
    Inventors: Xiuzhi S. Sun, Greggory S. Karr
  • Patent number: 6561787
    Abstract: Molding apparatus (10) is provided which allows use of a particulate non-liquid molding material (121) to produce a variety of articles, such as frustoconical barrel segments (122). The apparatus (10) includes a female mold segment (18) including generally annular inner and outer sidewalls (70, 76) and a complemental male mold section (20) having an annular sidewall unit (30). In use, a molding material (121) is placed between the sidewalls (70, 76) and the section (20) is shifted so that it telescopes within the section (18); this compresses the material (121) to a desired final shape, which is then hardened to yield the final product (122). An optional wear insert (26) can be used with female mold section (18), which can be replaced as needed and assists in cleaning of the apparatus (10).
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: May 13, 2003
    Assignees: Kansas State University Research Foundation, Kansas Advanced Technologies, Inc.
    Inventors: Xiuzhi S. Sun, Greggory S. Karr
  • Publication number: 20020132024
    Abstract: Molding apparatus (10) is provided which allows use of a particulate non-liquid molding material (121) to produce a variety of articles, such as frustoconical barrel segments (122). The apparatus (10) includes a female mold segment (18) including generally annular inner and outer sidewalls (70, 76) and a complemental male mold section (20) having an annular sidewall unit (30). In use, a molding material (121) is placed between the sidewalls (70, 76) and the section (20) is shifted so that it telescopes within the section (18); this compresses the material (121) to a desired final shape, which is then hardened to yield the final product (122). An optional wear insert (26) can be used with female mold section (18), which can be replaced as needed and assists in cleaning of the apparatus (10).
    Type: Application
    Filed: March 21, 2001
    Publication date: September 19, 2002
    Inventors: Xiuzhi S. Sun, Paul Seib, Greggory S. Karr
  • Patent number: 6337097
    Abstract: Biodegradable and edible composites for use as feed packaging containers are provided. Broadly, the composites are formed from a mixture comprising fiber mixed with a non-petroleum based, biodegradable adhesive formed by modifying a starch, protein, or protein-rich flour. The mixture has a moisture content of less than about 20% by weight, based upon the total weight of the mixture taken as 100% by weight. The mixture is then molded at pressures of from about 150-600 psi and temperatures of from about 150-500° F. to yield a final composite having a compressive strength of at least about 5 MPa. Preferred fibers include those derived from straw, corn stalks, sorghum stalks, soybean hulls, and peanut hulls. Preferred modifiers include NaOH, urea sodium dodecyl sulfate, sodium dodecylbenzene sulfonate, and guanidine hydrochloride.
    Type: Grant
    Filed: September 29, 1999
    Date of Patent: January 8, 2002
    Assignee: Kansas State University Research Foundation
    Inventors: Xiuzhi S. Sun, Paul Seib, Greggory S. Karr
  • Patent number: 6211325
    Abstract: Biodegradable polymers for use in forming high strength, degradable plastics and methods of forming the polymers are provided. Broadly, the methods comprise forming and heating a blended mixture of polylactic acid, a starch, and a linkage group for joining or copolymerizing the polylactic acid and starch. Preferred linkage groups comprise an isocyanate moiety, with diphenylmethylene diisocyanate, hexamethylene diisocyanate, and isophorone diisocyanate. The reacted mixture can then be formed into the desired final product which has high tensile strength, modulus of elasticity, percent elongation, and thermal stability.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: April 3, 2001
    Assignee: Kansas State University Research Foundation
    Inventors: Xiuzhi S. Sun, Paul Seib, Hua Wang