Patents by Inventor Xixian Jian

Xixian Jian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing mesaconine and related intermediaries thereof
    Patent number: 11465971
    Abstract: The present invention relates to a method for preparing mesaconine and related intermediaries. Specifically, in the method for preparing mesaconine of the present invention, aconitine extracted from the Aconitum soongaricum Stapf. of aconitum plant is used as a raw material and subjected to alkalization, acetylation, N-de-ethylation, N-methylation, and hydrolysis to obtain mesaconine. The method for preparing mesaconine in the present invention is simple in operation, high in yield, environmentally friendly and pollution-free, and suitable for industrial production.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: October 11, 2022
    Inventors: Fengpeng Wang, Yuefei Geng, Xixian Jian, Donglin Chen, Funeng Geng
  • Method For Preparing Mesaconine And Related Intermediaries Thereof
    Publication number: 20210040042
    Abstract: The present invention relates to a method for preparing mesaconine and related intermediaries. Specifically, in the method for preparing mesaconine of the present invention, aconitine extracted from the Aconitum soongaricum Stapf. of aconitum plant is used as a raw material and subjected to alkalization, acetylation, N-de-ethylation, N-methylation, and hydrolysis to obtain mesaconine. The method for preparing mesaconine in the present invention is simple in operation, high in yield, environmentally friendly and pollution-free, and suitable for industrial production.
    Type: Application
    Filed: January 23, 2019
    Publication date: February 11, 2021
    Applicant: Gooddoctor Pharmaceutical Group Co., Ltd.
    Inventors: Fengpeng Wang, Yuefei Geng, Xixian Jian, Donglin Chen, Funeng Geng
  • Preparation and drug composition of bis-benzyl-isoquinoline class alkaloids
    Patent number: 6617335
    Abstract: This invention relates to the preparation of bis-isoquinoline derivatives of general formula (I) and salts thereof, which possesses multi-drug resistance (MDR) reversal activities. Drug compositions and formulations comprising bis-isoquinoline derivatives of general formula (I) and salts thereof are provided for use as sensitivity enhancers in cancer chemotherapy. Methods for inhibiting MDR by treatment with bis-isoquinoline derivatives are also provided.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: September 9, 2003
    Assignee: Kanghong USA, Inc.
    Inventors: Fengpeng Wang, Li Wang, Jinsong Yang, Donglin Chen, Xixian Jian