Patents by Inventor Xizhi Guo

Xizhi Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CLONING AND EXPRESSION SYSTEM FOR T-CELL RECEPTORS
    Publication number: 20190040381
    Abstract: The invention provides a method for rapid cloning of T-cell receptors (TCRs) (e.g., paired ?? and ?? TCR chains) and B-cell receptors (BCRs) (e.g. paired IgH or IgK or Ig?) from single cells by CDR3 substitution using single cell PCR products and Gibson Assembly techniques and a pre-generated TCR (or BCR) library in an expression vector.
    Type: Application
    Filed: December 2, 2016
    Publication date: February 7, 2019
    Applicant: St. Jude Children's Research Hospital, Inc.
    Inventors: Paul Thomas, Xizhi Guo, Pradyot Dash