Abstract: A method for optimizing a Polar-RNNA quantizer of MLC NAND flash based on deep learning comprises the following steps: Step S1: transforming an MLC flash detection task into a deep learning task, and obtaining three hard-decision read thresholds based on a neural network; Step S2: expanding six soft-decision read thresholds based on the three hard-decision read thresholds; Step S3: constructing an LLR mapping table, and obtaining new LLR information of MLC flash based on the LLR mapping table; Step S4: symmetrizing an MLC flash channel, and performing density evolution; and Step S5: optimizing the soft-decision read thresholds based on a genetic algorithm to obtain an optimal quantization interval. According to the invention, polar codes can be directly used for MLC flash channels without the arduous work of MLC flash channel modeling, so that the reliability of MLC flash is effectively improved.

Abstract: The concepts include a user support system in the form of a microphone, a visual display arranged in a vehicle cabin, and a controller. The controller includes an instruction set that is executable to receive, via the microphone, a voice-based request from a user, and employ a virtual assistant to determine a user interaction in real time and to determine a specific intent for the voice-based request, including capturing metadata. A user interaction routine determines a user interaction parameter associated with the virtual assistant based upon the voice-based request from the user. A user sentiment analysis routine determines a user satisfaction parameter associated with the virtual assistant based upon the voice-based request from the user. The controller responds in real-time to the voice-based request based upon the user satisfaction parameter and the user interaction parameter that are associated with the virtual assistant.

Abstract: A page display method and apparatus for an application, and an electronic device are provided. The method includes: receiving a play instruction for multimedia content in the application; and in response to the play instruction, in the case that the multimedia content belongs to a preview stream of an online live broadcast, playing the multimedia content and displaying real-time information of the online live broadcast. The real-time information of the online live broadcast includes at least one of a live broadcast commentary or a live broadcast explanation.

Abstract: A fractal power converter and a method for constructing the fractal power converter, the method for constructing the fractal converter including: replacing a switch and/or an energy storage element of an asymmetric half-bridge sub-module with the same asymmetric half-bridge sub-module for at least two times, replacing a switch and/or an energy storage element of a symmetric half-bridge sub-module with the same symmetric half-bridge sub-module for at least two times, and replacing a switch and/or an energy storage element of an H-bridge sub-module with the same H-bridge sub-module for at least two times. Compared with a conventional high-voltage and large-current power converter, the fractal power converter may output any high-voltage and large-current waveform. The system is modularized, the structure is simple and extensible, and voltage and current may be evenly distributed among the modules. The control method is simple and easy to standardize. Multi-port parallel output is allowed.

Abstract: An automatic rain response system includes microphones of a vehicle, windshield wipers, and a controller. The microphones generate acoustic signals in response to rain. The controller is configured to receive a local weather condition, extract acoustic features from the acoustic signals, form feature vectors in response to the acoustic features and the local weather condition, classify the feature vectors to determine a current class among multiple classes, activate the windshield the wipers at a high speed in response to the current class being a heavy rain on a windshield class, activate the windshield wipers at a medium speed in response to the current class being a freezing rain on the windshield class, activate the windshield wipers at a low speed in response to the current class being a light rain on the windshield class, and deactivate the windshield wipers in response to the current class being a no rain class.

Abstract: A system for scenario context-aware voice assistant auto-activation is provided. The system includes a microphone configured for providing data related to a word or a phrase spoken by a user, an operational device, and a computerized scenario context-aware voice assistant controller. The controller includes programming to recognize the word or the phrase within the data and identify a scenario context of the word or the phrase. The controller further includes programming to utilize the scenario context to associate the word or the phrase with a scenario context feature trigger configured for indicating a desired command of the user and command the operational device based upon the scenario context feature trigger associated with the word or the phrase.

Abstract: The present disclosure provides single domain antibodies that bind to CD20, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.

Abstract: The present disclosure provides single domain antibodies that bind to CD22, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.

Abstract: Single domain antibodies that bind to Claudin18.2, and chimeric antigen receptors comprising same are provided. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.

Abstract: The present disclosure provides single domain antibodies that bind to CD19, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.

Abstract: A motor vehicle includes a body defining a passenger compartment and having opposing driver and passenger sides. The vehicle includes driver and passenger side mirrors. The driver side mirror has a sweep angle (?) and an elevation angle (?). The passenger side mirror has a sweep angle (?). The side mirrors are separated from each other by a distance (D). An adjustable driver seat has a height (H). An electronic controller, in response to position signals inclusive of angles (?), (?), and (?), the distance (D), and the height (H), calculates a three-dimensional (3D) driver head position of a driver of the vehicle, and thereafter uses the 3D driver head position to improve performance of a driver assist system device. Functions of the controller may be implemented as a method or recorded on a computer readable medium for execution by a processor.

Abstract: The technical field of preparation of organic compounds, and particularly to yeasts producing tyrosol or hydroxytyrosol and construction methods thereof. PcAAS and ADH-encoding DNA sequences are introduced into the yeast strain BY4741, to obtain a PcAAS-ADH recombinant yeast producing tyrosol. A PDC1 knockout cassette and a TyrA expression cassette are introduced into the PcAAS-ADH recombinant yeast to obtain a PcAAS-ADH-?PDC1-TyrA recombinant yeast producing tyrosol. A HpaBC encoding DNA sequence is introduced into the PcAAS-ADH-?PDC1-TyrA recombinant yeast, to obtain a PcAAS-ADH-HpaBC-?PDC1-TyrA recombinant yeast producing hydroxytyrosol. The construction of a tyrosol or hydroxytyrosol biosynthesis pathway in the yeast strain BY4741 enhances the production of tyrosol or hydroxytyrosol.

Abstract: A chimeric antigen receptor (CAR) comprising a polypeptide comprising an extracellular antigen binding domain comprising a first BCMA binding moiety and a second BCMA binding moiety, wherein the first BCMA binding moiety is a first anti-BCMA single domain antibody, and the second BCMA binding moiety is a second anti-BCMA sdAb; and wherein each of the first and second sdAb is a VHH domain.

Abstract: A method for text feedback includes: receiving, by a controller, an utterance from a user; determining, by an automatic speech recognition engine of the controller, a plurality of speech recognition results based on the utterance from the user, wherein the speech recognition results include probable commands; determining, by the automatic speech recognition engine of the controller, a plurality of confidence scores for each of the plurality of speech recognition results; determining, by the controller, a text characteristic for each of the plurality of probable commands as a function of the confidence scores for each of the plurality of speech recognition results; and commanding, by the controller, a display to show text corresponding to each of the plurality of probable commands with the text characteristic determined by the controller.

Abstract: A method for producing a stainless steel foil comprises the following steps: rolling a raw material steel coil in an intermediate rolling process comprising three rolling processes; rolling the finished product in the rolling process; annealing and straightening the finished product. The application also provides a stainless steel foil prepared by the method. The method can solve the defect that the high strength and high plasticity of the ultra-thin stainless steel foil are difficult to meet at the same time.

Abstract: Disclosed in the present invention are a polyvinyl alcohol (PVA)-based degradable plastic, a preparation method therefor and application thereof, and a recycling method therefor. The preparation method comprises the following steps: a PVA solution is subjected to a chemical grafting reaction under an acidic condition under the action of a modifier; there are a phenyl group, an aldehyde group, and at least one group capable of forming a hydrogen bond with PVA in a structural formula of the modifier. The polyvinyl alcohol-based degradable plastic provided in the present invention has the advantages of being high in transparency, high in mechanical strength, not affected by environmental humidity, easy to degrade, good in thermal stability and good in biocompatibility, and has the advantages of recyclability, low costs, easy large-scale preparation and the like.

Abstract: A method for synthesizing lacto-N-biose and belongs to the technical field of bioengineering and oligosaccharide synthesis. A multi-enzyme catalytic system with good biological safety and wide application, and an ATP regeneration cycle system is introduced into a multi-enzyme reaction system, so that the synthesis of lacto-N-biose and the utilization rate of substrates are improved. A novel lacto-N-biose synthetic route lays a foundation for large-scale industrial production of lacto-N-biose and has important economic values and social benefits. At the same time, the synthetic method is efficient, mild, simple, easy to operate, low in cost and suitable for industrial production, and has a high practical application value.

Abstract: A recombinant yeast is constructed by introducing an expressed gene of exogenous Fructose-6-phosphate phosphoketolase into a modified yeast cell, and the modified yeast cell is a yeast cell with a metabolic pathway for synthesizing tyrosol via Erythrose-4-phosphate and phosphoenolpyruvate. The present invention discloses for the first time that in the process of expressing Fructose-6-phosphate phosphoketolase in a yeast, Fructose-6-phosphate is synthesized into beta-D-Fructose 1,6-bisphosphate and also catalyzed into Erythrose-4-phosphate and Acetyl-phosphate, and Xylulose-5-phosphate is catalyzed into Glyceraldehydes-3-phosphate and Acetyl-phosphate, which change the metabolic flux distribution of carbon in the yeast, enhance the synthesis of Erythrose-4-phosphate as an important intermediate for the biosynthesis of tyrosol, optimize the metabolic pathway for synthesizing tyrosol, and increase the yields of tyrosol and its derivatives such as hydroxytyrosol.

Abstract: Disclosed herein are antigen binding units that specifically bind to CD47. Further disclosed herein are polynucleic acids encoding said antigen binding units, vectors comprising said polynucleic acids, and hybridomas and host cells comprising said vectors. Further provided herein are methods for inducing phagocytosis of CD47-expressing cells.

Abstract: Disclosed herein are anti-Claudin 18.2 antibodies and pharmaceutical compositions comprising the same. In some embodiments, also described herein are methods of treating a subject having a cancer with an anti-Claudin 18.2 antibody and methods of inducing cell kill effect with an anti-Claudin 18.2 antibody.