Patents by Inventor Xu He

Xu He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12681926
    Abstract: The present disclosure involves methods, apparatus, and systems for processing group-by operations in databases. In one example, a method includes receiving a query to perform a group-by operation based on first attributes and second attributes of a plurality of entities. The first attributes are private data owned by a first participant of a secure multi-party computation (MPC), and the second attributes are private data owned by a second participant of the secure MPC. The method further includes performing one-hot encoding on the first attributes to generate encoded first attributes, and calculating, based on secure MPC, a secret share of a dataset. The dataset includes the first set of numbers and the second attributes. The method further includes performing the group-by operation including arranging the plurality of entities into groups based on at least the encoded first attributes, and aggregating the second attributes of entities in each of the groups.
    Type: Grant
    Filed: January 16, 2025
    Date of Patent: July 14, 2026
    Assignee: Beijing Zitiao Network Technology Co., Ltd.
    Inventors: Yongchuan Niu, Dong Yin, Haohao Qian, Xu He, Li Wang, Qiang Yan
  • Publication number: 20260152555
    Abstract: Provided are CD112R-binding proteins, particularly anti-CD112R antibodies and antigen-binding fragments thereof. Further provided are compositions comprising the CD112R-binding proteins, nucleic acid molecule encoding the antigen-binding protein, and use thereof.
    Type: Application
    Filed: September 22, 2023
    Publication date: June 4, 2026
    Inventors: Jianhua SUI, Yajing YANG, Fang YANG, Jianhe CHEN, Juan LIU, Yao SHENG, Chunmei LIU, Fangfang REN, Dongxia HAO, Xu HE
  • Patent number: 12558840
    Abstract: A printer head for three-dimensional printing of a continuous fiber-reinforced thermoset composite may include a deposition syringe, a fiber housing, and a feeding tube. The deposition syringe may define a resin reservoir, an air chamber, and a first inlet port configured to deliver a first flow of air to the air chamber. The deposition syringe may include a syringe body and a piston. The syringe body may include an inlet section, a needle section, and a converging section disposed between the inlet section and the needle section. The fiber housing may define a fiber chamber and a second inlet port configured to deliver a second flow of air to the fiber chamber. The feeding tube may extend from the fiber chamber to the needle section and may be configured to receive the second flow of air therein and to guide a fiber from the fiber chamber to the needle section.
    Type: Grant
    Filed: August 31, 2022
    Date of Patent: February 24, 2026
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Kai Yu, Xu He, Martin Dunn, Arif Abdullah
  • Publication number: 20260050791
    Abstract: This disclosure provides a method, an apparatus, a device, a medium, and a program product for training a decision model. The method includes: determining a first policy using a supervised learning model and a second policy using a reinforcement learning model within the decision model based on training data; determining an imitation learning loss based on a difference between the first policy and the second policy; and training the decision model based on both the imitation learning loss and a reinforcement learning loss corresponding to the second policy. By combining the imitation learning loss and the reinforcement learning loss, a human-like decision model with excellent performance may be obtained, leveraging the expert data utilization capability of supervised learning and the strong generalization capacity of reinforcement learning. In some embodiments, the trained model is applied to autonomous driving for tasks such as lane-changing.
    Type: Application
    Filed: October 9, 2025
    Publication date: February 19, 2026
    Applicant: Shenzhen Yinwang Intelligent Technologies Co., Ltd.
    Inventors: Xu He, Dong Li, Hao Sun, Juncheng Li, Siyuan Cheng, Jianye Hao
  • Publication number: 20250384032
    Abstract: The present disclosure involves methods, apparatus, and systems for processing group-by operations in databases. In one example, a method includes receiving a query to perform a group-by operation based on first attributes and second attributes of a plurality of entities. The first attributes are private data owned by a first participant of a secure multi-party computation (MPC), and the second attributes are private data owned by a second participant of the secure MPC. The method further includes performing one-hot encoding on the first attributes to generate encoded first attributes, and calculating, based on secure MPC, a secret share of a dataset. The dataset includes the first set of numbers and the second attributes. The method further includes performing the group-by operation including arranging the plurality of entities into groups based on at least the encoded first attributes, and aggregating the second attributes of entities in each of the groups.
    Type: Application
    Filed: January 16, 2025
    Publication date: December 18, 2025
    Inventors: Yongchuan NIU, Dong YIN, Haohao QIAN, Xu HE, Li WANG, Qiang YAN
  • Patent number: 12479805
    Abstract: An indazole hydrazide compound, as represented in formula (I); wherein, R is selected from substituted alkyl, substituted alkenyl and substituted phenyl; substituent in the substituted alkyl and substituted alkenyl includes phenyl and/or substituted phenyl; R? is selected from H and alkyl. Compared with the prior art, the above indole hydrazide compound can be used as integrin av?3 receptor antagonist. Besides, it has obvious anti-prostate cancer activity and has a significant inhibitory effect on enzalutamide-resistant cell lines. In addition, the above-mentioned compound has obvious anti-tumor angiogenesis activity and can be used in the preparation of anti-tumor angiogenesis drugs to inhibit tumor angiogenesis.
    Type: Grant
    Filed: November 26, 2021
    Date of Patent: November 25, 2025
    Assignee: BEIJING BAHEAL CHENGCHUANG PHARMACEUTICAL RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Yimin Cui, Xiaocong Pang, Xu He, Yanlun Gu, Zhenming Liu, Song Song, Xia Zhao, Ying Zhou, Qian Xiang, Junling Zhang, Ran Xie, Xiaojiao Sun, Zhuo Zhang
  • Publication number: 20250356395
    Abstract: Methods, systems, and apparatus, including computer-readable storage media for content group generation for a content delivery campaign. Content groups are generated from a resource identifier and a description. Digital content items are created for each content group, including digital content from the resource identifier and the description, as well as new digital content items. Candidate content groups are ranked according to request coverage gain and optionally one or more other ranking criteria. Request coverage gain is a measure of how much more request coverage is gained through keywords of one content group relative to the request coverage of one or more other content groups. By ranking according to request coverage gain, the selected candidate content groups are differentiated relative to one another, capturing potential content requests that would otherwise be missed by a campaign of content groups not selected based on request coverage gain.
    Type: Application
    Filed: October 21, 2024
    Publication date: November 20, 2025
    Inventors: Sandeep Atluri, Xiaolan Zhou, Xu He, JYoung S Kim
  • Publication number: 20250144069
    Abstract: Provided herein are bilobalide derivative compounds, processes for making, methods of using, and uses thereof for preventing or treating neurological disease and cancer.
    Type: Application
    Filed: August 3, 2024
    Publication date: May 8, 2025
    Inventors: Wai Lung NG, Stephan Juergen Wolfgang SCHEEFF, Josefina XEQUE AMADA, Xiaoding JIANG, Xu HE
  • Publication number: 20250093436
    Abstract: In an method for detecting a closed loop in MRI: 3D coordinates of key characteristic points of an MRI examination subject are acquired; the 3D coordinates of the key characteristic points are adapted to a 3D body standard model, to obtain a 3D virtual body model of the examination subject; 3D surface regions of pre-designated body parts are extracted from the 3D virtual body model; based on pre-defined body parts where skin contact is likely to occur, a distance between 3D surface regions of two body parts in each body part pair are calculated; and in response to the distance between the 3D surface regions of the two body parts in any body part pair being less than a preset first threshold, a risk of a closed loop in the examination subject is determined.
    Type: Application
    Filed: September 20, 2024
    Publication date: March 20, 2025
    Applicant: Siemens Healthineers AG
    Inventors: Xu He, Luis Pedro Ribeiro Lopes, Fang Yong Sun, Hui Song, Jun Xiong, Kun Zhu
  • Publication number: 20250009960
    Abstract: The disclosure provides a manufacturing method for a backflow type irrigation needle tip, and a backflow type irrigation needle tip. In the manufacturing method, a pointed portion of the irrigation needle tip is a closed end. The method includes: setting a laser parameter of the laser apparatus, where the laser parameter includes a repetition frequency, single pulse energy, and a focal spot size; setting a diameter parameter of a laser machining trajectory; adjusting a laser beam for aiming to a designated portion of the irrigation needle tip to be machined, and adjusting a direction of the laser beam and an axial direction of the irrigation needle tip to form an angle, where a range of the angle ? is 10°??<90°; and activating the laser apparatus, and forming an inclined hole towards the closed end on a pipe wall of the irrigation needle tip.
    Type: Application
    Filed: September 23, 2024
    Publication date: January 9, 2025
    Inventor: Xu He
  • Publication number: 20240421766
    Abstract: A photovoltaic inverter and a temperature detection apparatus. The photovoltaic inverter includes a plurality of photovoltaic terminals, a converter, a printed circuit board (PCB), a temperature detection circuit, and a controller. The plurality of photovoltaic terminals are correspondingly connected to a plurality of photovoltaic modules. The PCB includes an electrically conductive layer and at least one thermally conductive insulation layer. One end of each photovoltaic terminal is soldered on the PCB, and the other end is connected to a corresponding photovoltaic module in a thermally conductive manner. The electrically conductive layer transmits electric energy generated by the plurality of photovoltaic modules to the converter. Each thermally conductive insulation layer conducts heat generated by at least one photovoltaic terminal. The temperature detection circuit detects a temperature of each thermally conductive insulation layer.
    Type: Application
    Filed: August 26, 2024
    Publication date: December 19, 2024
    Applicant: Huawei Digital Power Technologies Co., Ltd.
    Inventors: Xu HE, Fangpo ZHANG
  • Patent number: 12016710
    Abstract: The disclosure relates to techniques for scan preparation in a medical imaging system. The technique includes triggering a 3D camera acquiring a 2D color and depth image of a patient when a patient bed is at an origin position, inputting the image into a pre-trained first body information model to obtain position information of multiple body feature site points, and calculating position information of multiple candidate scanning regions in the patient bed coordinate system. The technique further includes providing the position information of the multiple candidate scanning regions to a medical imaging application apparatus, so that the medical imaging application apparatus determines position information of a current scanning region in the patient bed coordinate system and controls the patient bed to move the current scanning region to a scanning center of a medical imaging device according to the position of the patient bed relative to the scanning center.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: June 25, 2024
    Assignee: Siemens Healthineers AG
    Inventors: Jun Xiong, Kun Zhu, Fang Yong Sun, Hui Song, Xu He
  • Publication number: 20240175954
    Abstract: A magnetic resonance scanning method including: detecting the positions of individual characteristic points of interest and the positions and sizes of individual sites of interest of a target human body in the current MR scan; calculating a scan start position and a total scan range of the current MR scan according to the detected positions of the individual characteristic points of interest and the positions and sizes of the individual sites of interest of the target human body; and performing the current MR scan according to the calculated scan start position and total scan range of the MR scan. In an aspect, the scanning method is fully automatic.
    Type: Application
    Filed: November 27, 2023
    Publication date: May 30, 2024
    Applicant: Siemens Healthcare GmbH
    Inventors: Jun Xiong, Le Zhang, Fang Yong Sun, Hui Song, Xu He
  • Patent number: 11702391
    Abstract: The present disclosure relates to compounds of Formula I: that act as inhibitors of NLRP3 inflammasomes; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with inflammation and inflammaging, including hearing loss and other diseases associated with aging.
    Type: Grant
    Filed: March 23, 2022
    Date of Patent: July 18, 2023
    Assignees: BIOAGE LABS, INC., HITGEN, INC.
    Inventors: George Hartman, Xu He, Jia Du, Lifang Zhang, Paul Humphries, Kevin Edward Leif Wilhelmsen
  • Patent number: 11692576
    Abstract: A single groove single-sided fastener comprises: a rivet consisting of a rivet head, a polish rod, a locking groove, a tail pulling groove and a tail tooth in sequence, and a lantern ring consisting of a sleeve and a dead head; a tail of the rivet is of a single groove short-tail structure, a ratio of a length of the tail pulling groove to a total length of the tail tooth is 0.1˜1.5, an included angle between a bottom generatrix of the tail pulling groove and an axis of the rivet is ?30°˜0°, two axial ends of the bottom of the tail pulling groove and the tail of the tail tooth are of a fillet transition structure, a ratio of a length of a straight part of the tail tooth to the total length of the tail tooth is 0.1˜1.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: July 4, 2023
    Assignee: MEISHAN CRRC FASTENING SYSTEM CO., LTD
    Inventors: Shibo Wang, Yu Liu, Tao Deng, Yunlong Jia, Xiangyun Zhao, Chuanqi Li, Xu He, Wei Li, Long Guo
  • Publication number: 20230130502
    Abstract: Computer software architectures are disclosed that use improved machine learning techniques for data science and data clustering. Computer operations are improved by more efficiently and effectively processing relevant data. Based on a clustering model, initial clusters of taxonomical pairs of entity classifications and entity sub-classifications using taxonomical-level textual data representative of one or more aspects of electronic transactions associated with the taxonomical pairs can be determined, wherein the clustering model has been generated based on machine learning applied to past clusters of past taxonomical pairs of entity classifications and entity sub-classifications other than the initial clusters of the taxonomical pairs, and iteratively refining the initial clusters, according to a similarity criterion, resulting in tuned clusters.
    Type: Application
    Filed: October 21, 2021
    Publication date: April 27, 2023
    Inventors: Yaotian Zou, Aaron A Trube, Xu He
  • Publication number: 20230119925
    Abstract: A single groove single-sided fastener comprises: a rivet consisting of a rivet head, a polish rod, a locking groove, a tail pulling groove and a tail tooth in sequence, and a lantern ring consisting of a sleeve and a dead head; a tail of the rivet is of a single groove short-tail structure, a ratio of a length of the tail pulling groove to a total length of the tail tooth is 0.1˜1.5, an included angle between a bottom generatrix of the tail pulling groove and an axis of the rivet is ?30°˜?0°, two axial ends of the bottom of the tail pulling groove and the tail of the tail tooth are of a fillet transition structure, a ratio of a length of a straight part of the tail tooth to the total length of the tail tooth is 0.1˜1.
    Type: Application
    Filed: May 26, 2020
    Publication date: April 20, 2023
    Inventors: SHIBO WANG, YU LIU, TAO DENG, YUNLONG JIA, XIANGYUN ZHAO, CHUANQI LI, XU HE, WEI LI, LONG GUO
  • Publication number: 20230123945
    Abstract: The present disclosure relates to a method and system for monitoring on route transportations. The method includes obtaining a driving route of a target vehicle; obtaining a reference position on the driving route away from a first current position of the target vehicle; determining a second current position of the target vehicle after a reference time; determining a distance between the second current position and the reference position is greater than a preset distance; and sending a signal to a target terminal indicating that the target vehicle is off-route.
    Type: Application
    Filed: December 15, 2022
    Publication date: April 20, 2023
    Applicant: BEIJING DIDI INFINITY TECHNOLOGY AND DEVELOPMENT CO., LTD.
    Inventors: Beibei ZHANG, Xu HE, Chao TANG, Zhaoxue WU
  • Publication number: 20230121175
    Abstract: The invention discloses a pulling rivet for fasten-connecting a conductive material. It consists of a rivet and a lantern ring, wherein the rivet comprises a dead head, a polish rod, a locking groove, a pulling groove and a short tail, the lantern ring comprises a flange, a deformation area and a clamping tooth, and a sharp protrusion is arranged on a contact surface of an inner side of the dead head and a fasten-coupling piece. The sharp protrusions of the present invention can be embedded into the surface of the fastening piece to prevent the sliding between the fasten-coupling piece and the rivet, and because the sharp protrusions are embedded into the surface of the fasten-coupling piece to form a tightly fitted whole, which improves the conductivity of the rivet and the frame.
    Type: Application
    Filed: May 26, 2020
    Publication date: April 20, 2023
    Inventors: XU HE, YUNLONG JIA, CHUANQI LI, SHIBO WANG, QIN ZHANG, SHUAI DONG, ZONGYANG ZUO, YU LIU, TAO DENG, JUAN JIANG
  • Bus
    Patent number: D1054915
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: December 24, 2024
    Assignee: BYD COMPANY LIMITED
    Inventors: Wolfgang Josef Egger, Wenquan Tang, Zheng Tao, Jin Jin, Xu He, Yuecong Niu, Liang Chen, Zhipeng Lin