Abstract: The invention provides immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions and methods thereof.

Abstract: The present disclosure relates to use of a protein kinase C (PKC) inhibitor in the treatment or prevention of proliferative diseases. The disclosure also relates to corresponding pharmaceutical formulations, uses, methods, combinations, and related disclosure embodiments. The disclosure further relates to use of a pharmaceutical combination comprising a PKC inhibitor and another therapeutic agent, such as an MDM2 inhibitor, in the treatment or prevention of a proliferative disease.

Abstract: A micro-electrical-mechanical-system (MEMS) switching device including a first MEMS switch having a first and second terminal, and a second MEMS switch having a third and fourth terminal. The device also includes first and second input conductors, and first and second output conductors. The first input conductor electrically connects the second terminal to the third terminal. The second input conductor electrically connects an input port to the first input conductor. The first output conductor electrically connects a first output port to the first terminal. The second output conductor electrically connects a second output port to the fourth terminal. A first path from the input port to the first output port, and a second path from the input port to the second output port, have substantially identical electrical characteristics.

Abstract: A micro-relay switch array may comprise an array of micro-relays disposed on a substrate, and a cap disposed over the array of micro-relays, thereby encapsulating the array of micro-relays. The micro-relay switch array may further comprise an array of through-substrate vias (TSVs) associated with the array of micro-relays, arranged such that columns of TSVs alternate with columns of micro-relays, and a plurality of device electrical conductors, each of which electrically couples one of the TSVs of the array of TSVs directly to at least two of the micro-relays. The micro-relay switch array may further comprise a plurality of TSV electrical conductors, each of which electrically couples at least two TSVs together. Each micro-relay of the array of micro-relays may be a micro-electromechanical system (MEMS) switch. The substrate and cap may be glass, and the TSVs may be through-glass vias.

Abstract: According to one embodiment, a radar device includes a transmission module including a transmission antenna and first integrated circuits, a reception module including a reception antenna and second integrated circuits, and a third integrated circuit. Each of the first integrated circuits includes first transmission circuits, first reception circuits, and a first signal generation circuit. Each of the second integrated circuits includes second transmission circuits, second reception circuits, and a second signal generation circuit. The third integrated circuit includes third transmission circuits, third reception circuits, and a third signal generation circuit.

Abstract: According to one embodiment, a system includes first to fourth transmission antennas, a plurality of reception antennas, and a processor. The processor is configured to acquire a first signal of radio waves which are transmitted by the first and third transmission antennas in a case where the measurement target is at a first position, acquire a second signal of radio waves which are transmitted by the second and fourth transmission antennas in a case where the measurement target is at a second position, and generate information of the measurement target by using the first and second signals. A first interval between the first and third transmission antennas and a second interval between the second and fourth transmission antennas are the same.

Abstract: A first housing and a second housing of a foldable device are rotatably connected through a rotating shaft mechanism. A first chamber is provided between a flexible display of the device and the first housing, a second chamber is provided between the flexible display of the device and the second housing, and a third chamber is provided between the flexible display of the device and the rotating shaft mechanism. A flexible thermal sheet is disposed in space formed by the first chamber, the second chamber, and the third chamber. The flexible thermal sheet is fastened to the first housing, passes through the third chamber along the flexible display, and extends to the second chamber. The flexible thermal sheet slidably cooperates with the rotating shaft mechanism, the second housing, and parts that correspond to the rotating shaft mechanism and the second housing and that are of the flexible display.

Abstract: Provided is a method to operate a user equipment operating in a cellular network different from the user equipment's home cellular network, the user equipment being configured to carry out, following a periodic home network scan cycle, a measurement attempt to the home cellular network, the user equipment operating in a reduced activity mode, comprising reduced measurement activity time periods, comprising the step of comparing the periodic home network scan cycle with the reduced activity mode's reduced measurement activity time period, in case the periodic home network scan cycle is shorter than the reduced measurement activity time period, amending the periodic home network scan cycle.

Abstract: According to one embodiment, a radar device includes antenna panels. The antenna panels include a first transmission panel, first reception panel, and second reception panel, or the antenna panels include a first transmission panel, second transmission panel, and first reception panel. The first transmission panel includes antennas at intervals of m times a substantially half wavelength where m is a positive integer of two or more. The first reception panel includes antennas at intervals of n times the substantially half wavelength where n is a positive integer of two or more, and m and n are coprime to each other.

Abstract: The present disclosure relates to use of a protein kinase C (PKC) inhibitor in the treatment or prevention of proliferative diseases. The disclosure also relates to corresponding pharmaceutical formulations, uses, methods, combinations, and related disclosure embodiments. The disclosure further relates to use of a pharmaceutical combination comprising a PKC inhibitor and another therapeutic agent, such as an MDM2 inhibitor, in the treatment or prevention of a proliferative disease.

Abstract: A method of fabricating and packaging an ohmic micro-electro-mechanical system (MEMS) switch device may comprise constructing the switch device on an insulating substrate. The switch device may have contacts that consist of a platinum-group metal. The method may further comprise forming an oxidized layer of the platinum-group metal on an outer surface of each of the one or more contacts. The method may further comprise bonding an insulating cap to the insulating substrate, to hermetically seal the switch device. The bonding may occur in an atmosphere that has a proportion of oxygen within a range of 0.5% to 30%, such that, after the switch device has been hermetically sealed within the sealed cavity, an atmosphere within the sealed cavity has a proportion of oxygen within the range of 0.5% to 30%. The platinum-group metal may be ruthenium, and the oxidized layer of the platinum-group metal may be ruthenium dioxide.

Abstract: A composite structure includes a first layer and a second layer that are stacked, the first layer is configured to connect the second layer and a flexible display, and the second layer is configured to dissipate heat. Each of the first layer and the second layer includes a first surface and a second surface opposite to each other, where the first surface of the first layer is proximate to the flexible display, and the first surface of the second layer is proximate to the second surface of the first layer. An elastic modulus of the first layer is greater than or equal to an elastic modulus of the second layer, and a coefficient of thermal conductivity of the first layer is less than or equal to a coefficient of thermal conductivity of the second layer.

Abstract: Systems and methods for enabling energy efficient Random Access Channel (RACH) are provided. A method performed by a network node includes one or more of: being configured with an original RACH configuration; receiving a preamble in a RACH Occasion; dynamically changing a RACH-configuration period and/or RACH frequency multiplexing configuration according to whether a preamble was received; reconfiguring to a performance optimized configuration; starting one or more timers: keeping the current RACH configuration until the timer(s) reaches the specified time; if fewer than a threshold preambles are received, reconfiguring with the original PRACH configuration; and if more than a threshold preamble are received, resetting and/or restarting a running timer. An energy efficient RACH configuration allows the network node receivers to have a longer sleep time and operate over a narrower bandwidth. As such more energy is saved when the network is in idle mode and there are no/little RACH attempts.

Abstract: A method of providing optimized settings of graphics parameters for a computer gaming application includes: consolidating data related to settings of graphics parameters for different computer hardware equipment and respective performance values; training a machine learning model based on the consolidated data; determining a weight for each setting of a graphics parameter, by the trained machine learning model; for each set of graphics parameters, predicting a performance value achievable by the computer gaining application when it is executed on a specific type of computer, by the trained machine learning model; assigning a priority value to each graphics parameter based on its contribution to the performance value; choosing or generating at least one set of graphics parameters providing an optimized performance value, based on the predicted performance value associated with each set of graphics parameters and the determined weight for each graphics parameter and/or based on the assigned priority value.

Abstract: A carrier device in semiconductor processing equipment includes a base and an edge ring. The base includes a base body configured to carry a wafer and has an outer diameter smaller than a diameter of the wafer. The edge ring surrounds the base and has an outer diameter greater than the diameter of the wafer. An outer circumferential surface of the base body faces and is spaced from an inner circumferential surface of the edge ring to form a first annular channel. The first annular channel communicates with a gas supply system. When the base body carries the wafer, an upper surface of the edge ring faces and is spaced from a lower surface of the wafer to form a second annular channel. The first annular channel communicates with the second annular channel.

Abstract: A device for switching a differential signal includes an input port, a first output port, a second output port, a first micro electromechanical system (MEMS) switch, and a second MEMS switch. The first and second MEMS switches selectively couple the input port to either the first output port or the second output port. The differential input port is separated into two single-ended paths. One single-ended path is switched through the first MEMS switch, and the other single-ended path is switched through the second MEMS switch. The single-ended paths are spatially matched with respect to length and orientation, and are at least partially distributed through at least two layers of electrical conductors, with adjacent layers of electrical conductors separated by electrically insulating layers.

Abstract: A system includes a first device with a primary screening area; a second device with a secondary screening area different from the primary screening area; and processor circuitry. The first device includes a first antenna and a first communication device; the second device includes a second antenna and a second communication device. The first antenna irradiates an electromagnetic wave to a target in the primary screening area and receives an electromagnetic wave reflected by the target; the second antenna irradiates an electromagnetic wave to the target in the secondary screening area and receives an electromagnetic wave reflected by the target; and the processor circuitry determines a possibility that the target possesses a predetermined article, based on a level of the electromagnetic wave received by the first antenna, and determines that screening by the second device is required for the target in accordance with the possibility.

Abstract: According to one embodiment, an antenna device comprises an antenna panel including a first transmission antenna, a first reception antenna, and a second reception antenna, and a rotation device configured to rotate the antenna panel. A first radio wave is irradiated from the first transmission antenna when a rotation angle of the antenna panel is a first angle and a reflected radio wave of the first radio wave is received by the first reception antenna and the second reception antenna. A second radio wave is irradiated from the first transmission antenna when the rotation angle is a second angle and a reflected radio wave of the second radio wave is received by the first reception antenna and the second reception antenna.

Abstract: The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods.

Abstract: A micro-relay switch array may comprise an array of micro-relays disposed on a substrate, and a cap disposed over the array of micro-relays, thereby encapsulating the array of micro-relays. The micro-relay switch array may further comprise an array of through-substrate vias (TSVs) associated with the array of micro-relays, arranged such that columns of TSVs alternate with columns of micro-relays, and a plurality of device electrical conductors, each of which electrically couples one of the TSVs of the array of TSVs directly to at least two of the micro-relays. The micro-relay switch array may further comprise a plurality of TSV electrical conductors, each of which electrically couples at least two TSVs together. Each micro-relay of the array of micro-relays may be a micro-electromechanical system (MEMS) switch. The substrate and cap may be glass, and the TSVs may be through-glass vias.