Abstract: The invention disclosed herein relates to aza-quinoline compounds of Formula (I), pharmaceutical compositions comprising such compounds, and the use of such compounds for treating a disease or condition mediated by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination thereof.

Abstract: Provided aza-quinoline compounds of Formula (I), pharmaceutical compositions comprising such compounds; and the use of such compounds for treating a disease or condition mediate by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination thereof.

Abstract: A electronic device includes a USB Type-C interface, a switching circuit, a first signal path, and a second signal path. The USB Type-C interface is configured to connect to a USB Type-C device. The switching circuit is connected to the USB Type-C interface, the first signal path, and the second signal path. When the USB Type-C interface is connected to the USB Type-C device, the first signal path is connected to the USB Type-C interface through the switching circuit, and a level of a first pin of the USB Type-C interface is a first level. When the USB Type-C interface is disconnected from the USB Type-C device, the second signal path is connected to the USB Type-C interface through the switching circuit, and a level of the first pin is a second level. The first level is greater than the second level.

Abstract: The present disclosure relates to a process for acid-catalyzed decomposition of aryl ?-hydroperoxide with a continuous flow tubular reactor. The process is a novel process performed in a tubular reactor, taking the aryl ?-hydroperoxide such as cumene hydroperoxide (CHP) as a raw material and taking acids as a catalyst, performing acid-catalyzed decomposition of the aryl ?-hydroperoxide solution in a short reaction time ranging from tens of seconds to several minutes, thereby obtaining the phenols; wherein an inert component may be filled in the reactor, so that the effects of heat transmission and mass transfer can be enhanced. The aryl ?-hydroperoxide and acid are respectively introduced by a metering pump into a mixing module to be mixed, and then enter the tubular reactor to be reacted so as to produce the products such as phenols.

Abstract: A electronic device includes a USB Type-C interface, a switching circuit, a first signal path, and a second signal path. The USB Type-C interface is configured to connect to a USB Type-C device. The switching circuit is connected to the USB Type-C interface, the first signal path, and the second signal path. When the USB Type-C interface is connected to the USB Type-C device, the first signal path is connected to the USB Type-C interface through the switching circuit, and a level of a first pin of the USB Type-C interface is a first level. When the USB Type-C interface is disconnected from the USB Type-C device, the second signal path is connected to the USB Type-C interface through the switching circuit, and a level of the first pin is a second level. The first level is greater than the second level.

Abstract: A product and product packaging suitable for retail sale. The product can include a package carton comprising external and internal surfaces, wherein the internal surface includes a plurality of fold lines and first and second graphic portions, wherein the graphic portions are suitable to provide at least a portion of at least one of a toy, a game, a collectible, and an educational tool. The first graphic portion and the second graphic portion are bilaterally symmetrical to each other relative to at least one fold line of the plurality of fold lines. In another embodiment, the product is for use by a first consumer group but not a second consumer group, while the at least one of the toy, game, collectible, and educational tool is for use by the second consumer group but not the first consumer group.

Abstract: The present disclosure relates to a process for acid-catalyzed decomposition of aryl ?-hydroperoxide with a continuous flow tubular reactor. The process is a novel process performed in a tubular reactor, taking the aryl ?-hydroperoxide such as cumene hydroperoxide (CHP) as a raw material and taking acids as a catalyst, performing acid-catalyzed decomposition of the aryl ?-hydroperoxide solution in a short reaction time ranging from tens of seconds to several minutes, thereby obtaining the phenols; wherein an inert component may be filled in the reactor, so that the effects of heat transmission and mass transfer can be enhanced. The aryl ?-hydroperoxide and acid are respectively introduced by a metering pump into a mixing module to be mixed, and then enter the tubular reactor to be reacted so as to produce the products such as phenols.

Abstract: The present invention relates to the technical field of peroxide decomposition, and discloses a method for preparing phenol, which comprises the following steps: (1) mixing cumene hydroperoxide and liquid acid or solid acid with a solvent to form a homogeneous solution or uniformly dispersed system; (2) loading the homogeneous solution or uniformly dispersed system of cumene hydroperoxide with a homogeneous solution or uniformly dispersed system of acid into a preheating module and preheating in a micro-channel continuous flow mode, preliminarily mixing the preheated materials for reaction in a mixing module in a micro-channel continuous flow mode, and then further mixing the materials for reaction in a series of mixing and reaction module groups in a micro-channel continuous flow mode, to obtain phenol.

Abstract: The present invention relates to the technical field of peroxide decomposition, and discloses a method for preparing phenol, which comprises the following steps: (1) mixing cumene hydroperoxide and liquid acid or solid acid with a solvent to form a homogeneous solution or uniformly dispersed system; (2) loading the homogeneous solution or uniformly dispersed system of cumene hydroperoxide with a homogeneous solution or uniformly dispersed system of acid into a preheating module and preheating in a micro-channel continuous flow mode, preliminarily mixing the preheated materials for reaction in a mixing module in a micro-channel continuous flow mode, and then further mixing the materials for reaction in a series of mixing and reaction module groups in a micro-channel continuous flow mode, to obtain phenol.

Abstract: The invention relates to a device and method for detecting changes in background of successive images. More particularly, the invention relates to a device and method for detecting changes in background of successive images by obtaining vertically accumulated values and horizontally accumulated values from multiple binary images of previous image and current image, obtaining pairs of rows and pairs of columns based on the vertically accumulated values and horizontally accumulated values, and transforming pairs of rows and pairs of columns using Hough transformation. Also, the invention relates to an interface system including background changes detecting device and display device connected to the background changes detecting device.

Abstract: Electrochemical methods and materials for the detection of arsenic. In one aspect, arsenic is detected using a working electrode comprising particulate platinum. In another aspect, arsenic is detected using an electrode comprising indium tin oxide and particulate gold. Also provided are methods for the production of electrodes which involve the electrodeposition of gold onto indium tin oxide.

Abstract: The invention relates to a device and method for detecting changes in background of successive images. More particularly, the invention relates to a device and method for detecting changes in background of successive images by obtaining vertically accumulated values and horizontally accumulated values from multiple binary images of previous image and current image, obtaining pairs of rows and pairs of columns based on the vertically accumulated values and horizontally accumulated values, and transforming pairs of rows and pairs of columns using Hough transformation. Also, the invention relates to an interface system including background changes detecting device and display device connected to the background changes detecting device.

Abstract: Electrochemical methods and materials for the detection of arsenic. In one aspect, arsenic is detected using a working electrode comprising particulate platinum. In another aspect, arsenic is detected using an electrode comprising indium tin oxide and particulate gold. Also provided are methods for the production of electrodes which involve the electrodeposition of gold onto indium tin oxide.