Abstract: The present disclosure provides a method and a system therefore for processing wafer. The method includes: extracting a first gas from a chamber via a first route; blocking a second route used to be pumped down to chuck a wafer placed in the chamber, wherein the second route connects the chamber and the first route; and providing a second gas via a third route to purge a junction of the first route and the second route.

Abstract: The present application relates to azaaromatic amide derivatives for the treatment of cancer. Specifically, the present application relates to a preparation method and use of azaaromatic amide derivatives. The present application relates to azaaromatic amide derivatives and anilino-pyrimidine compounds represented by formula (I), formula (II), formula (III), formula (IV), and formula (V), and pharmaceutically acceptable salts thereof; the compounds or salts thereof can be used to treat or prevent a disease or disorder by regulating certain mutant forms of epidermal growth factor receptors. The present application also relates to a pharmaceutical composition comprising the compounds or salts thereof, and a method for treating various diseases mediated by EGFR, or HER2, or HER4 by using the compounds and salts thereof.

Abstract: Provided are a recombinase polymerase amplification (RPA)-PAND based enterovirus virus typing detection kit and a rapid sensitive detection method, where the detection kit includes a PfAgo protein three gDNAs (g1/g2/g3), MB and its corresponding gDNA (gMB) combination for specifically detection of enteroviruses EV71, CVA6, CVA10, CVA16 and the universal enterovirus (EVU). RPA-HFMD-PAND rapid nucleic acid detection methods for typing detection of common enterovirus type A pathogens EV71, CVA6, CVA10, CVA16 and enterovirus universal EVU are successfully established based on PfAgo protein mediated target detection in combination with an RPA technology. The method has the advantages of high sensitivity, high specificity, low cost, relatively low position targeting restriction, simple reaction system and no aerosol pollution, and can conduct multi-channel nucleic acid detection.

Abstract: The present disclosure provides a method of making a semiconductor device. The method includes forming a semiconductor stack on a substrate, wherein the semiconductor stack includes first semiconductor layers of a first semiconductor material and second semiconductor layers of a second semiconductor material alternatively stacked on the substrate; patterning the semiconductor stack and the substrate to form a trench and an active region being adjacent the trench; epitaxially growing a liner of the first semiconductor material on sidewalls of the trench and sidewalls of the active region; forming an isolation feature in the trench; performing a rapid thermal nitridation process, thereby converting the liner into a silicon nitride layer; and forming a cladding layer of the second semiconductor material over the silicon nitride layer.

Abstract: The present invention discloses a Fe—Al intermetallic compound filter element and a preparation method thereof, which relates to the field of powder metallurgy and filtration technology. In view of the drawback in the prior art that using a fiber felt as a filtration layer reduces stability and reliability of a filter, the present invention provides an Fe—Al intermetallic compound filter element, which comprises: at least two filter-element parts, and a rebar connecting the at least two filter-element parts transversely by means of welding, wherein, the filter-element parts each comprises at least two segments of Fe—Al intermetallic compound filter-element powder tube and a connector connecting the at least two segments of Fe—Al intermetallic compound filter-element powder tube end-to-end by means of welding; and wherein, the at least two segments of Fe—Al intermetallic compound filter-element powder tube each comprises a substrate framework and a surface filtration membrane.

Abstract: Disclosed is a test method for measuring a force situation of a tree-shaped spatial node, and the test method is realized by a reaction frame device. The reaction frame device includes a raft foundation and a reaction frame fixedly mounted on the raft foundation, a cavity is formed inside the reaction frame to accommodate a tree-shaped spatial node; a main pipe of the tree-shaped spatial node is plumb-fastened to the raft foundation, and a force measurement assembly is arranged in an upper space of the cavity, which can simultaneously apply force of a set value to each branch pipe in the tree-shaped spatial node and detect a combined force applied to the tree-shaped spatial node. The method can simultaneously and accurately apply static force to each branch pipe, thereby effectively predicting the overall working condition of the tree-shaped spatial node.

Abstract: The present application relates to the crystalline form of the mesylate salt, the crystalline form of the hydrochloride salt and the crystalline form of the maleate salt of a compound of formula (I): The present application also relates to a method for treating non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutation using the crystalline forms. The present application also relates to synthetic routes for the compound of formula (I).

Abstract: A semiconductor processing tool includes: a process chamber into which a semiconductor wafer is loaded; a support for securing the wafer loaded into the chamber tool; an inlet which introduces a first gas into the chamber for processing the wafer; and an exhaust system that exhausts gas from the chamber. The exhaust system includes: a first line coupled to the chamber to exhaust gas from the chamber; and a pump to draw gas through the first line from the chamber. The tool further includes a heating module having: a second line coupled to the first and a supply of a second gas, the second gas being flowed through the second line from the supply into the first line; and a heating element contained in the second line, the heating element heating the second gas in the second line before the second gas is flowed into the first line.

Abstract: The present invention discloses a Fe—Al-based metal membrane and preparation method thereof, which relate to the technical field concerning gas-solid separation under high-temperature, low-pressure working conditions, and mainly address the defects of conventional metal filter elements in the prior art such as high filtration resistance and low flux under low-pressure working environments. The preparation method of the present invention comprises the steps of: stirring and defoaming a mixture composed of a Fe—Al-based metal powder and an organic-additive-added water-based solvent, thus obtaining a cast slurry; casting a uniform membrane layer on a metal substrate layer having a required thickness on a casting machine, and performing drying treatment on it, thus obtaining a membrane green body; and, placing the dried membrane green body in a sintering furnace for degreasing, sintering, and alloy phase ordering treatments, respectively, thus obtain a prepared Fe—Al-based metal membrane.

Abstract: A valve for throttling gas flow from a semiconductor processing tool includes a valve body. A shaft extends through the valve body. The shaft defines an internal cavity and a first opening communicating with the internal cavity. A first deflector is positioned on the shaft proximate the first opening and directed at a first interface between the shaft and the valve body. A method for throttling gas flow from a semiconductor processing tool includes providing a gas in an internal cavity defined in a shaft of a valve and directing the gas through an opening defined in the shaft and communicating with the bore toward an interface between the shaft and a valve body of the valve supporting the shaft.

Abstract: A gas flow accelerator may include a body portion, and a tapered body portion including a first end integrally formed with the body portion. The gas flow accelerator may include an inlet port connected to the body portion and to receive a process gas to be removed from a semiconductor processing tool by a main pumping line. The semiconductor processing tool may include a chuck and a chuck vacuum line to apply a vacuum to the chuck to retain a semiconductor device. The tapered body portion may be configured to generate a rotational flow of the process gas to prevent buildup of processing byproduct on interior walls of the main pumping line. The gas flow accelerator may include an outlet port integrally formed with a second end of the tapered body portion. An end portion of the chuck vacuum line may be provided through the outlet port.

Abstract: The invention provides, in one aspect, a compound represented by formula (I) or a stereoisomer, tautomer or pharmaceutical salt thereof, and use thereof in preparation of a medicament for preventing and/or treating estrogen receptor (ER)-related diseases or disorders.

Abstract: A gas flow accelerator may include a body portion, and a tapered body portion including a first end integrally formed with the body portion. The gas flow accelerator may include an inlet port connected to the body portion and to receive a process gas to be removed from a semiconductor processing tool by a main pumping line. The semiconductor processing tool may include a chuck and a chuck vacuum line to apply a vacuum to the chuck to retain a semiconductor device. The tapered body portion may be configured to generate a rotational flow of the process gas to prevent buildup of processing byproduct on interior walls of the main pumping line. The gas flow accelerator may include an outlet port integrally formed with a second end of the tapered body portion. An end portion of the chuck vacuum line may be provided through the outlet port.

Abstract: An anti-FGFR2 antibody, an encoding nucleic acid of the antibody, a vector and host cell for the expression and production thereof, an antibody-drug conjugate, and a pharmaceutical composition comprising the antibody. The present invention further relates to the use of the antibody molecule in a drug for diagnosing a cancer caused by FGFR2-pathway-related dysregulation, and the use of the antibody or antibody-drug conjugate in the preparation of a medicament for treating a cancer caused by FGFR2-pathway-related dysregulation, in particular gastric cancer.

Abstract: An apparatus, a method, and a storage medium for database pagination. The apparatus, method, and storage medium are configured to perform following processes, including: acquiring a pagination request from a user; determining a query parameter based on the pagination request; determining a corresponding pagination pattern and a request data amount based on the query parameter; determining a target query mode based on the request data amount; generating a query task based on the pagination pattern and the target query mode; obtaining at least one first query result based on the query task; determining a target result set based on the at least one first query result; and paging the target result set based on the pagination pattern and the target query mode to obtain multiple pages of pagination data.

Abstract: The present invention discloses a Fe—Al-based metal porous membrane and a preparation method thereof, which relate to the technical field of industrial gas-solid and liquid-solid separation and purification, and mainly address problems in the prior art, such as cracking-prone and peeling of a membrane layer of an existing Fe—Al-based metal porous membrane during its preparation and use. The preparation method of the present invention comprises the steps of: adding a Fe—Al-based metal powder and a metal fiber powder into an organic-additive-added water-based solvent, and mixing them into a slurry; casting the slurry, through a casting machine, to form a membrane green body on a metal substrate layer, and letting it dry; and placing the dried membrane green body in a sintering furnace, to remove organic substances and perform high-temperature sintering and predetermined-temperature reaction synthesis.

Abstract: The present invention discloses a method for welding Fe—Al intermetallic compound microporous material and a welded part made thereby, and the present invention relates to the field of welding technology. For the problem in the prior art that there is great difficulty in welding between Fe—Al microporous material and dense stainless steel, the method for welding Fe—Al intermetallic compound microporous material, in accordance with the present invention, comprises the following steps: turning on “welding torch fuel-gas” of a fusion-welding machine, and turning on welding shielding gas in a shield; adjusting welding parameters of the welding machine and parameter of the welding shielding gas in the shield for a fusion welding process; switching on the welding machine, and using welding wire as welding filler for welding Fe—Al intermetallic compound microporous material to dense stainless steel; and, cooling after completion of the welding.

Abstract: The present application provides an access traffic limiting method and apparatus, a device, a storage medium, and a computer program product. The method includes: when detecting that the number of access requests transmitted by a plurality of terminal devices to an access interface exceeds a first preset value, intercepting for each individual terminal device, outside the access interface, a target access request transmitted by the terminal device; determining the number of times that the target access request is received within a preset time period; and transmitting the target access request to the access interface if the number of times is greater than a second preset value. According to the present application, the success rate of interface accessing by a user can be improved.

Abstract: A brain tumor types distinguish system includes an image outputting device and a server computing device. The image outputting device outputs at least three brain images captured from the position of a brain tumor. The server computing device pre-stores a plurality of distinguish pathways corresponding to different types of brain tumors. The server computing device includes an image receiving module, an image pre-processing module, a data comparison module and a distinguish module. The image receiving module receives the brain images. The image pre-processing module pre-processes the brain images to obtain corresponding processed images thereof. The data comparison module compares the brain images and the processed images with the distinguish pathways to obtain at least three comparison results. The distinguish module statistically analyzes the comparison results to obtain a distinguish result.

Abstract: The present application relates to a salt formed from a compound of formula (I) with an acid: wherein the acid is selected from hydrochloric acid, methanesulfonic acid, benzenesulfonic acid, ethanesulfonic acid, maleic acid, hydrobromic acid, citric acid, L-tartaric acid, and p-toluenesulfonic acid. The present application also relates to a method for treating non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutation using the salt.