Patents by Inventor Xuanhao ZHANG

Xuanhao ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for promoting replication of bovine rhinotracheitis viruses using cold atmospheric plasma
    Patent number: 11530390
    Abstract: A method for promoting replication of infectious bovine rhinotracheitis viruses using cold atmospheric plasma, including: irradiating a medium for Madin-Darby bovine kidney cells with a cold atmospheric plasma generator; adding the irradiated medium to the Madin-Darby bovine kidney cells; and adding infectious bovine rhinotracheitis viruses for incubation. The time required for treatment is 2 min allowing for a simple and rapid operation. The plasma is used for the indirect treatment of cells with a uniform process and a controllable intensity. The replication of the infectious bovine rhinotracheitis viruses in the Madin-Darby bovine kidney cells is significantly promoted by co-incubation in the treated DMEM for 1 hour, so that the high levels of infectious bovine rhinotracheitis viruses obtained can be used for vaccine production after inactivation, improving the vaccine production efficiency.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: December 20, 2022
    Assignee: JIANGSU CAPTAIN BIOTECHNOLOGY CO., LTD.
    Inventors: Xiaofeng Dai, Xuanhao Zhang, Jianying Zhang
  • METHOD FOR PROMOTING REPLICATION OF BOVINE RHINOTRACHEITIS VIRUSES USING COLD ATMOSPHERIC PLASMA
    Publication number: 20190330598
    Abstract: A method for promoting replication of infectious bovine rhinotracheitis viruses using cold atmospheric plasma, including: irradiating a medium for Madin-Darby bovine kidney cells with a cold atmospheric plasma generator; adding the irradiated medium to the Madin-Darby bovine kidney cells; and adding infectious bovine rhinotracheitis viruses for incubation. The time required for treatment is 2 min allowing for a simple and rapid operation. The plasma is used for the indirect treatment of cells with a uniform process and a controllable intensity. The replication of the infectious bovine rhinotracheitis viruses in the Madin-Darby bovine kidney cells is significantly promoted by co-incubation in the treated DMEM for 1 hour, so that the high levels of infectious bovine rhinotracheitis viruses obtained can be used for vaccine production after inactivation, improving the vaccine production efficiency.
    Type: Application
    Filed: April 18, 2019
    Publication date: October 31, 2019
    Inventors: Xiaofeng DAI, Xuanhao ZHANG, Jianying ZHANG