Patents by Inventor Xuanhe Zhao

Xuanhe Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12209207
    Abstract: The present disclosure generally relates to a stretchable anti-fogging tape (SAT) that can be applied to diverse transparent materials with varied curvatures for persistent fogging prevention. The SAT comprises three synergistically-combined transparent layers: i) a stretchable middle layer with high elastic recovery to keep transparent materials tightly bound; ii) an anti-fogging top layer to impart hydrophilicity to transparent materials; and iii) an adhesive bottom layer to form robust yet reversible adhesion between transparent materials and SATs. The SAT can be configured to have water condensate form a predominantly continuous film thereon in response to a high humidity environment At least two applications are demonstrated, including the SAT-adhered eyeglasses and goggles for clear fog-free vision, and the SAT-adhered condensation cover for efficient solar-powered freshwater production.
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: January 28, 2025
    Assignee: Massachusetts Institute of Technology
    Inventors: Gang Chen, Xuanhe Zhao, Shaoting Lin, Yoichiro Tsurimaki
  • Publication number: 20240399019
    Abstract: Methods of implanting biomaterials and devices in a patient, such as methods that include arranging an adhesive composition between and in contact with a biomaterial or a device, and a surface of a tissue of the patient. An adhesive composition may be configured to form at a surface of a tissue a conformal interface that reduces or minimizes infiltration of inflammatory cells at the conformal interface.
    Type: Application
    Filed: March 15, 2024
    Publication date: December 5, 2024
    Inventors: Jingjing Wu, Jue Deng, Hyunwoo Yuk, Xuanhe Zhao
  • Patent number: 12157801
    Abstract: Adhesion of conducting polymers on diverse insulating and conductive substrates via a hydrophilic adhesion layer, where one or more functional groups may be disposed between the substrate and the hydrophilic adhesion layer. Adhesion of the conducting polymers on the substrates is such that adhesion is maintained or substantially maintained in wet physiological environments.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: December 3, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Xuanhe Zhao, Hyunwoo Yuk, Akihisa Inoue
  • Patent number: 12084604
    Abstract: A dry shape memory adhesive material for adhering a target surface in the presence of fluid and for providing tunable mechanical contraction of an adhered surface. The dry shape memory adhesive material is pre-stretched and dried to provide an adhesive structure that implements a hydration-based shape memory mechanism to achieve both uniaxial and biaxial contractions of the adhered surface. According to preferred embodiments, the shape memory adhesive material includes a combination of one or more hydrophilic polymers or copolymers, one or more amine coupling group, and one or more cross linkers.
    Type: Grant
    Filed: February 8, 2022
    Date of Patent: September 10, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Xuanhe Zhao, Hyunwoo Yuk, Heejung Roh
  • Patent number: 12054653
    Abstract: An adhesive material that provides fast and robust adhesion on wet surfaces, where the adhesion formed is detachable on-demand. The adhesive material is formed of one or more hydrophilic polymers or copolymers grafted with one or more amine coupling groups via a plurality of cleavable physical bonds and/or cleavable covalent bonds and one or more cross linkers. Application of the adhesive material on a wet surface causes the adhesive material to absorb liquid to thereby swell the adhesive material to form a layer of hydrogel, resulting in the formation of temporary crosslinks followed by covalent crosslinks with the surface. Introducing a triggering agent cleaves the cleavable physical bonds and/or cleavable covalent bonds to allow for non-traumatic detachment of the adhesive material from the surface.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: August 6, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Xuanhe Zhao, Hyunwoo Yuk, Xiaoyu Chen
  • Publication number: 20240238476
    Abstract: A method of adhering wet tissues together includes providing a dry adhesive material that contains one or more hydrophilic polymers, one or more amine coupling groups, and one or more cross linkers. The method including the steps of placing the dry adhesive material in contact with one or more wet tissue surfaces; allowing the dry adhesive material to absorb liquid from the one or more wet surfaces to thereby swell the adhesive material; allowing instant crosslinking by intermolecular interactions between the adhesive material and the one or more wet surfaces; and allowing quick covalent crosslinking between the adhesive material and the one or more wet surfaces.
    Type: Application
    Filed: January 24, 2024
    Publication date: July 18, 2024
    Inventors: Xuanhe Zhao, Hyunwoo Yuk
  • Publication number: 20240144904
    Abstract: Described herein are window retrofits including a monolithic silica aerogel slab having (i) an average haze value of <5% as calculated in accordance with ASTM standard D1003-13 and (ii) a U-factor of <0.5 BTU/sf/hr/° F., and a transparent polymer envelope sealed at an internal pressure of ?1 atmosphere, wherein the monolithic silica aerogel slab is encapsulated in the transparent polymer envelope. The monolithic aerogel slab can have a transmittance>94% at 8 mm thickness. The window retrofit can be bonded to a glass sheet.
    Type: Application
    Filed: June 27, 2023
    Publication date: May 2, 2024
    Inventors: Evelyn N. Wang, Gang Chen, Xuanhe Zhao, Elise M. Strobach, Bikramjit S. Bhatia, Lin Zhao, Sungwoo Yang, Lee A. Weinstein, Thomas A. Cooper, Shaoting Lin
  • Publication number: 20240132758
    Abstract: A tissue adhesive material that provides fast and robust adhesion even on tissue surfaces covered in bodily fluids. The tissue adhesive material is formed of a hydrophobic matrix and a plurality of bioadhesive microparticles dispersed within the hydrophobic matrix configured such that disposing the adhesive material directly on a fluid covered surface and applying pressure causes the (a) hydrophobic matrix to repel the fluid, (b) the bioadhesive particles to compress forming an adhesive layer, and (c) the bioadhesive particles to form temporary crosslinks followed by covalent crosslinks with the surface.
    Type: Application
    Filed: December 11, 2023
    Publication date: April 25, 2024
    Inventors: Xuanhe Zhao, Hyunwoo Yuk, Xinyu Mao, Christoph Nabzdyk
  • Patent number: 11904067
    Abstract: Dry adhesive materials, particularly in the form of a film or tape, for adhering one or more wet surfaces comprising: (i) one or more hydrophilic polymers; (ii) one or more amine coupling groups, and (iii) one or more cross linkers. The dry adhesive material, when placed in contact with the one or more wet surfaces, absorbs liquid from the one or more wet surfaces, swells to form temporary crosslinking with the wet surface, and forms covalent crosslinking with the one or more wet surfaces.
    Type: Grant
    Filed: April 11, 2020
    Date of Patent: February 20, 2024
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Xuanhe Zhao, Hyunwoo Yuk
  • Patent number: 11884845
    Abstract: A tissue adhesive material that provides fast and robust adhesion even on tissue surfaces covered in bodily fluids. The tissue adhesive material is formed of a hydrophobic matrix and a plurality of bioadhesive microparticles dispersed within the hydrophobic matrix configured such that disposing the adhesive material directly on a fluid covered surface and applying pressure causes the (a) hydrophobic matrix to repel the fluid, (b) the bioadhesive particles to compress forming an adhesive layer, and (c) the bioadhesive particles to form temporary crosslinks followed by covalent crosslinks with the surface.
    Type: Grant
    Filed: December 3, 2020
    Date of Patent: January 30, 2024
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Xuanhe Zhao, Hyunwoo Yuk, Xinyu Mao, Christoph Nabzdyk
  • Publication number: 20240009346
    Abstract: A shape memory adhesive material for adhering and contracting wounds, particularly diabetic wounds, to facilitate their closure and healing. The shape memory adhesive is pre-stretched and dried to provide an adhesive structure with a pre-programmed strain, wherein the adhesive is capable of rapid robust adhesion followed by predictive contraction upon contact with a wet surface. According to preferred embodiments, the shape memory adhesive material includes a combination of one or more hydrophilic polymers or copolymers, one or more amine coupling group, and one or more cross linkers.
    Type: Application
    Filed: February 11, 2022
    Publication date: January 11, 2024
    Inventors: Xuanhe Zhao, Hyunwoo Yuk, Heejung Roh, Aristidis Veves, Georgios Theocharidis
  • Patent number: 11850290
    Abstract: Provided herein, in some embodiments, are hydrogel-elastomer and hydrogel-alginate devices, compositions and associated methods to encapsulate living cells.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: December 26, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy Kuan-Ta Lu, Xinyue Liu, Tzu-Chieh Tang, Eléonore Claire Tham, Xuanhe Zhao
  • Publication number: 20230331892
    Abstract: This disclosure relates to modified polyurethanes, specifically polyurethanes modified with one or more lipophilic groups, and tough organogels comprising such modified polyurethanes.
    Type: Application
    Filed: April 18, 2023
    Publication date: October 19, 2023
    Inventors: Xuanhe Zhao, Xinyue Liu, Xiaoyu Chen
  • Patent number: 11779422
    Abstract: Robotic devices and methods for performing minimally invasive procedures on the vascular system, particularly cerebrovascular and endovascular neurosurgical procedures, where a submillimeter-scale continuum robotic device is configured and adapted for active steering and navigation based on external magnetic actuation. The submillimeter-scale continuum robotic device includes an elongate body having an inner core and an outer shell, where the outer shell is fabricated of an elastomeric material having a plurality of ferromagnetic particles dispersed therein.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: October 10, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Xuanhe Zhao, Yoonho Kim
  • Publication number: 20230277159
    Abstract: Systems and methods are provided for on-person wearable electronic devices configured for extended periods of wear. A couplant may be provided that is made of a soft anti-dehydrating, and hydrogel-elastomer hybrid material. A bioadhesive may connect the couplant the electronic devices and the person. The couplant may serve as a coupling and transmission for information to or from the electronic device.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 7, 2023
    Inventors: Xuanhe ZHAO, Xiaoyu CHEN, Chonghe WANG
  • Patent number: 11749247
    Abstract: Described herein are window retrofits including a monolithic silica aerogel slab having (i) an average haze value of <5% as calculated in accordance with ASTM standard D1003-13 and (ii) a U-factor of <0.5 BTU/sf/hr/° F., and a transparent polymer envelope sealed at an internal pressure of ?1 atmosphere, wherein the monolithic silica aerogel slab is encapsulated in the transparent polymer envelope. The monolithic aerogel slab can have a transmittance >94% at 8 mm thickness. The window retrofit can be bonded to a glass sheet.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: September 5, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Evelyn N. Wang, Gang Chen, Xuanhe Zhao, Elise M. Strobach, Bikramjit S. Bhatia, Lin Zhao, Sungwoo Yang, Lee A. Weinstein, Thomas A. Cooper, Shaoting Lin
  • Patent number: 11638903
    Abstract: Enhanced cleaning of a fouled membrane is achieved via controlled deformation in a method wherein a feed composition, comprising a solvent and dissolved components, flows into a retentate side of a membrane module. The solvent passes through the membrane from the retentate side to a permeate or draw side of the membrane module while retaining the dissolved components on the membrane. As a foulant accumulates on either side of the membrane, a driving force is generated across the membrane, wherein the membrane responds cyclically by deforming back and forth toward the permeate or draw side and toward the retentate side. The foulant is dislodged from the membrane via mechanical fatigue at the foulant-membrane interface caused by the deformation of the membrane and contact with a spacer in contact with the membrane.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: May 2, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Omar Labban, Grace Goon, John H. Lienhard, Xuanhe Zhao
  • Publication number: 20220403220
    Abstract: The present disclosure generally relates to a stretchable anti-fogging tape (SAT) that can be applied to diverse transparent materials with varied curvatures for persistent fogging prevention. The SAT comprises three synergistically-combined transparent layers: i) a stretchable middle layer with high elastic recovery to keep transparent materials tightly bound; ii) an anti-fogging top layer to impart hydrophilicity to transparent materials; and iii) an adhesive bottom layer to form robust yet reversible adhesion between transparent materials and SATs. The SAT can be configured to have water condensate form a predominantly continuous film thereon in response to a high humidity environment At least two applications are demonstrated, including the SAT-adhered eyeglasses and goggles for clear fog-free vision, and the SAT-adhered condensation cover for efficient solar-powered freshwater production.
    Type: Application
    Filed: June 6, 2022
    Publication date: December 22, 2022
    Inventors: Gang Chen, Xuanhe Zhao, Shaoting Lin, Yoichiro Tsurimaki
  • Publication number: 20220259463
    Abstract: A dry shape memory adhesive material for adhering a target surface in the presence of fluid and for providing tunable mechanical contraction of an adhered surface. The dry shape memory adhesive material is pre-stretched and dried to provide an adhesive structure that implements a hydration-based shape memory mechanism to achieve both uniaxial and biaxial contractions of the adhered surface. According to preferred embodiments, the shape memory adhesive material includes a combination of one or more hydrophilic polymers or copolymers, one or more amine coupling group, and one or more cross linkers.
    Type: Application
    Filed: February 8, 2022
    Publication date: August 18, 2022
    Inventors: Xuanhe Zhao, Hyunwoo Yuk, Heejung Roh
  • Publication number: 20220223130
    Abstract: Described herein are window retrofits including a monolithic silica aerogel slab having (i) an average haze value of <5% as calculated in accordance with ASTM standard D1003-13 and (ii) a U-factor of <0.5 BTU/sf/hr/° F., and a transparent polymer envelope sealed at an internal pressure of ?1 atmosphere, wherein the monolithic silica aerogel slab is encapsulated in the transparent polymer envelope. The monolithic aerogel slab can have a transmittance >94% at 8 mm thickness. The window retrofit can be bonded to a glass sheet.
    Type: Application
    Filed: October 21, 2021
    Publication date: July 14, 2022
    Inventors: Evelyn N. Wang, Gang Chen, Xuanhe Zhao, Elise M. Strobach, Bikramjit S. Bhatia, Lin Zhao, Sungwoo Yang, Lee A. Weinstein, Thomas A. Cooper, Shaoting Lin