Patents by Inventor Xuanmin He

Xuanmin He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190159796
    Abstract: Described herein is a system and method for identifying elastic lamina during interventional procedures, such as atherectomy. Such identification can be used to avoid trauma to the external elastic lamina during the procedure.
    Type: Application
    Filed: November 16, 2018
    Publication date: May 30, 2019
    Inventors: John B. SIMPSON, Xuanmin HE, Ryan RADJABI, Richard R. NEWHAUSER
  • Patent number: 10130386
    Abstract: Described herein is a system and method for identifying elastic lamina during interventional procedures, such as atherectomy. Such identification can be used to avoid trauma to the external elastic lamina during the procedure.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: November 20, 2018
    Assignee: Avinger, Inc.
    Inventors: John B. Simpson, Xuanmin He, Ryan Radjabi, Richard R. Newhauser
  • Publication number: 20160135832
    Abstract: Described herein is a system and method for identifying elastic lamina during interventional procedures, such as atherectomy. Such identification can be used to avoid trauma to the external elastic lamina during the procedure.
    Type: Application
    Filed: July 8, 2014
    Publication date: May 19, 2016
    Inventors: John B. SIMPSON, Xuanmin HE, Ryan RADJABI, Richard R. NEWHAUSER
  • Publication number: 20140005534
    Abstract: The present invention relates to methods and devices for predicting restenosis, and for treating atherosclerosis to prevent or reduce the incidence of restenosis. Methods of predicting restenosis in a stenosed peripheral artery may include quantitative histology of the vessel. For example, a method of treating a stenosed artery (and particularly a peripheral artery) may include the steps of determining a level of hypercellularity and one or more of the lipid-richness and extent of inflammatory cell inclusion in the tissue. An index of restenosis based on the hypercellularity and lipid richness and/or extent of inflammatory cell inclusion in the tissue may be determined. Systems for treating or preventing restenosis may include one or more imaging modalities for imaging tissue regions and determining the level of hypercellularity and one or more of the degree of lipid-richness and the extent of inflammatory cell inclusion in the tissue region.
    Type: Application
    Filed: September 5, 2013
    Publication date: January 2, 2014
    Inventors: Xuanmin HE, John B. SIMPSON, Michael H. ROSENTHAL, John F. BLACK
  • Patent number: 8548571
    Abstract: The present invention relates to methods and devices for predicting restenosis, and for treating atherosclerosis to prevent or reduce the incidence of restenosis. Methods of predicting restenosis in a stenosed peripheral artery may include quantitative histology of the vessel. For example, a method of treating a stenosed artery (and particularly a peripheral artery) may include the steps of determining a level of hypercellularity and one or more of the lipid-richness and extent of inflammatory cell inclusion in the tissue. An index of restenosis based on the hypercellularity and lipid richness and/or extent of inflammatory cell inclusion in the tissue may be determined. Systems for treating or preventing restenosis may include one or more imaging modalities for imaging tissue regions and determining the level of hypercellularity and one or more of the degree of lipid-richness and the extent of inflammatory cell inclusion in the tissue region.
    Type: Grant
    Filed: December 8, 2010
    Date of Patent: October 1, 2013
    Assignee: Avinger, Inc.
    Inventors: Xuanmin He, John B. Simpson, Michael H. Rosenthal, John F. Black
  • Publication number: 20110263936
    Abstract: The present invention relates to methods and devices for predicting restenosis, and for treating atherosclerosis to prevent or reduce the incidence of restenosis. Methods of predicting restenosis in a stenosed peripheral artery may include quantitative histology of the vessel. For example, a method of treating a stenosed artery (and particularly a peripheral artery) may include the steps of determining a level of hypercellularity and one or more of the lipid-richness and extent of inflammatory cell inclusion in the tissue. An index of restenosis based on the hypercellularity and lipid richness and/or extent of inflammatory cell inclusion in the tissue may be determined. Systems for treating or preventing restenosis may include one or more imaging modalities for imaging tissue regions and determining the level of hypercellularity and one or more of the degree of lipid-richness and the extent of inflammatory cell inclusion in the tissue region.
    Type: Application
    Filed: December 8, 2010
    Publication date: October 27, 2011
    Inventors: Xuanmin He, John B. Simpson, Michael H. Rosenthal, John F. Black
  • Publication number: 20070270708
    Abstract: The invention provides methods, devices and systems for collecting breast ductal fluid comprising cellular material and other useful markers for analysis. The methods typically comprise access of at least one breast duct and collecting materials from that duct separate from all other ducts in the breast. The devices comprise ductal access devices that provide the opportunity to collect fluid from a single duct separate from all the other ducts in the breast. The systems employ the methods and devices that used together provide systems for analysis of a breast condition in a patient specific to accessed breast ducts. The methods, devices and systems are particularly useful for indentification of breast precancer or cancer in patient.
    Type: Application
    Filed: July 24, 2007
    Publication date: November 22, 2007
    Inventors: David Hung, Christopher Ken, Xuanmin He, Phillip Olsen, Julian Nikolchev, Shawn O'Leary, Pam Sayavong
  • Patent number: 7204829
    Abstract: Apparatus, methods and kits for simultaneous delivery of a fluid or other substance to two or more breast milk ducts are provided. The fluid can be delivered for a variety of purposes including lavage of the ducts and administering an agent for therapeutic, prophylactic, or diagnostic purposes.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: April 17, 2007
    Assignee: Cytyc Corporation
    Inventors: David Hung, Xuanmin He
  • Publication number: 20060095017
    Abstract: Apparatus, methods and kits for simultaneous delivery of a fluid or other substance to two or more breast milk ducts are provided. The fluid can be delivered for a variety of purposes including lavage of the ducts and administering an agent for therapeutic, prophylactic, or diagnostic purposes.
    Type: Application
    Filed: December 14, 2005
    Publication date: May 4, 2006
    Inventors: David Hung, Xuanmin He
  • Patent number: 7029462
    Abstract: Apparatus, methods and kits for simultaneous delivery of a fluid or other substance to two or more breast milk ducts are provided. The fluid can be delivered for a variety of purposes including lavage of the ducts and administering an agent for therapeutic, prophylactic, or diagnostic purposes.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: April 18, 2006
    Assignee: Cytyc Corporation
    Inventors: David Hung, Xuanmin He
  • Publication number: 20040092894
    Abstract: Apparatus, methods and kits for simultaneous delivery of a fluid or other substance to two or more breast milk ducts are provided. The fluid can be delivered for a variety of purposes including lavage of the ducts and administering an agent for therapeutic, prophylactic, or diagnostic purposes.
    Type: Application
    Filed: June 27, 2003
    Publication date: May 13, 2004
    Applicant: Cytyc Health Corporation
    Inventors: David Hung, Xuanmin He
  • Patent number: 6585706
    Abstract: Apparatus, methods and kits for simultaneous delivery of a fluid or other substance to two or more breast milk ducts are provided. The fluid can be delivered for a variety of purposes including lavage of the ducts and administering an agent for therapeutic, prophylactic, or diagnostic purposes.
    Type: Grant
    Filed: February 12, 2002
    Date of Patent: July 1, 2003
    Assignee: Cytyc Health Corporation
    Inventors: David Hung, Xuanmin He
  • Patent number: 6494859
    Abstract: Methods, kits, and apparatus for obtaining cellular, chemical, and other materials from breast ducts are described. A single milk duct is accessed and washed with a washing fluid to obtain marker materials from the lining the duct. The washing fluid is then collected, and the marker materials in the washing fluid identified and analyzed. Usually, the washing fluid is introduced using a syringe through a lumen of a dual-lumen catheter. The ductal volume is filled with the washing fluid and excess fluid flows outwardly through a second lumen of the dual-lumen catheter, from which it is collected. Methods and kits provide for collection of fluid and cells by a lavage procedure that includes applying external pressure to the breast to improve the yield of fluid and cells from the breast duct.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: December 17, 2002
    Assignee: The Regents of the University of California
    Inventors: Susan M. Love, David Hung, Xuanmin He
  • Publication number: 20020107502
    Abstract: Apparatus, methods and kits for simultaneous delivery of a fluid or other substance to two or more breast milk ducts are provided. The fluid can be delivered for a variety of purposes including lavage of the ducts and administering an agent for therapeutic, prophylactic, or diagnostic purposes.
    Type: Application
    Filed: February 12, 2002
    Publication date: August 8, 2002
    Applicant: Pro Duct Health, Inc.
    Inventors: David Hung, Xuanmin He
  • Patent number: 6413228
    Abstract: The invention provides methods, devices and systems for collecting breast ductal fluid comprising cellular material and other useful markers for analysis. The methods typically comprise access of at least one breast duct and collecting materials from that duct separate from all other ducts in the breast. The devices comprise ductal access devices that provide the opportunity to collect fluid from a single duct separate from all the other ducts in the breast. The systems employ the methods and devices that used together provide systems for analysis of a breast condition in a patient specific to accessed breast ducts. The methods, devices and systems are particularly useful for indentification of breast precancer or cancer in patient.
    Type: Grant
    Filed: December 28, 1999
    Date of Patent: July 2, 2002
    Assignee: Pro Duct Health, Inc.
    Inventors: David Hung, Christopher G. M. Ken, Xuanmin He, Phillip M. Olsen, Julian Nikolchev, Shawn O'Leary, Pam Sayavong
  • Publication number: 20020019017
    Abstract: Methods, kits, and apparatus for obtaining cellular, chemical, and other materials from breast ducts are described. A single milk duct is accessed and washed with a washing fluid to obtain marker materials from the lining the duct. The washing fluid is then collected, and the marker materials in the washing fluid identified and analyzed. Usually, the washing fluid is introduced using a syringe through a lumen of a dual-lumen catheter. The ductal volume is filled with the washing fluid and excess fluid flows outwardly through a second lumen of the dual-lumen catheter, from which it is collected. Methods and kits provide for collection of fluid and cells by a lavage procedure that includes applying external pressure to the breast to improve the yield of fluid and cells from the breast duct.
    Type: Application
    Filed: April 28, 1999
    Publication date: February 14, 2002
    Inventors: SUSAN M. LOVE, DAVID HUNG, XUANMIN HE
  • Publication number: 20020010405
    Abstract: The invention provides methods, devices and systems for collecting breast ductal fluid comprising cellular material and other useful markers for analysis. The methods typically comprise access of at least one breast duct and collecting materials from that duct separate from all other ducts in the breast. The devices comprise ductal access devices that provide the opportunity to collect fluid from a single duct separate from all the other ducts in the breast. The systems employ the methods and devices that used together provide systems for analysis of a breast condition in a patient specific to accessed breast ducts. The methods, devices and systems are particularly useful for indentification of breast precancer or cancer in patient.
    Type: Application
    Filed: July 19, 2001
    Publication date: January 24, 2002
    Inventors: David Hung, Christopher G.M. Ken, Xuanmin He, Phillip M. Olsen, Julian Nikolchev, Shawn O'Leary, Pam Sayavong
  • Publication number: 20020002343
    Abstract: The invention provides methods, devices and systems for collecting breast ductal fluid comprising cellular material and other useful markers for analysis. The methods typically comprise access of at least one breast duct and collecting materials from that duct separate from all other ducts in the breast. The devices comprise ductal access devices that provide the opportunity to collect fluid from a single duct separate from all the other ducts in the breast. The systems employ the methods and devices that used together provide systems for analysis of a breast condition in a patient specific to accessed breast ducts. The methods, devices and systems are particularly useful for indentification of breast precancer or cancer in patient.
    Type: Application
    Filed: July 19, 2001
    Publication date: January 3, 2002
    Inventors: David Hung, Christopher G.M. Ken, Xuanmin He, Phillip M. Olsen, Julian Nikolchev, Shawn O'Leary, Pam Sayavong