Abstract: The present invention provides a method to treat and/or prevent febrile neutropenia and Grade 3/4 neutropenia. The method comprises application a Declined mobilizing granulocyte colony-stimulating factor (De-mobilized G-CSF) at a selected time, and a controlled dosage depended on the severity of neutropenia. The present invention also provides evidences to identify the De-mobilized G-CSF and High-mobilized G-CSF, and a method for preparing the De-mobilized G-CSF.

Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.

Abstract: A wireless communication device includes a receiver circuit, a phase shift control circuit, and a digital phase-locked loop (DPLL) circuit. The receiver circuit includes a down-converter circuit that is used to apply down-conversion to an input signal according to a local oscillator (LO) signal. The phase shift control circuit is used to generate a phase shift signal. The DPLL circuit is used to generate the LO signal locked to an initial frequency under a frequency-lock state. In response to the phase shift signal, the DPLL circuit is further used to make the LO signal have a different frequency without leaving the frequency-lock state.

Abstract: A battery pack includes a battery column and a liquid cooling tube. The battery column includes at least two batteries, and the batteries are arranged in a first direction. The liquid cooling tube is disposed on a surface of the battery column and is configured to dissipate heat for the batteries. The liquid cooling tube includes cooling portions, and the cooling portions are portions having orthographic projections on the battery column. The orthographic projections of the cooling portions on the battery column are cooling regions. The cooling portions extend in a second direction, and the second direction is not parallel to the first direction.

Abstract: A novel method for performing replication of messages in a network that bridges one or more physical networks to an overlay logical network is provided. A physical gateway provides bridging between network nodes of a physical network and virtual machines in the overlay logical network by serving as an endpoint of the overlay logical network. The physical gateway does not replicate messages from the bridged physical network to destination endpoints in the overlay logical network directly, but instead tunnels the message-to-be-replicated to a designated tunnel endpoint in the overlay logical network. The designated tunnel endpoint in turn replicates the message that was tunneled to it to other endpoints in the overlay logical network.

Abstract: Compositions that include cationic surfactants and methods of synthesizing compositions that include cationic surfactants. The surfactants include a quaternary amine and a saturated or unsaturated alkyl chain with 4 to 28 carbons. The surfactants can be generated by reacting a fatty acid modified with an amino alkyl group and an epihalohydrin in the presence of a base. The cationic surfactants can be generated by reacting a fatty acid modified with an amino alkyl group, an epihalohydrin, and a carboxylic acid. The cationic surfactants can be generated by reacting a carboxylic acid, an epihalohydrin, and a catalyst to afford a halo-substituted alkyl ester, followed by reacting the halo-substituted alky ester with a fatty acid modified with an amino alkyl group.

Abstract: Provided herein are KRN2 gene controlling kernel row number in plant, molecular markers closely linked to KRN2 and their application in molecular breeding.

Abstract: The present invention provides an artificial dressing and a use of the artificial dressing for promoting wound healing. The artificial dressing includes a gelatin and a fungal extract.

Abstract: The present invention belongs to the field of pharmaceutical manufacturing technology. The present invention provides a pharmaceutical composition of a conjugate and a preparation method thereof. The pharmaceutical composition is preferably administered by injection. The docetaxel conjugate has a structural formula as shown in the following formula: (I).

Abstract: Crystalline 4-((L-valyl)oxy)butanoic acid, methods of preparing crystalline 4-((L-valyl)oxy)butanoic acid, pharmaceutical compositions of crystalline 4-((L-valyl)oxy)butanoic acid, and methods of treatment using crystalline 4-((L-valyl)oxy)butanoic acid are disclosed.

Abstract: A novel method for performing replication of messages in a network that bridges one or more physical networks to an overlay logical network is provided. A physical gateway provides bridging between network nodes of a physical network and virtual machines in the overlay logical network by serving as an endpoint of the overlay logical network. The physical gateway does not replicate messages from the bridged physical network to destination endpoints in the overlay logical network directly, but instead tunnels the message-to-be-replicated to a designated tunnel endpoint in the overlay logical network. The designated tunnel endpoint in turn replicates the message that was tunneled to it to other endpoints in the overlay logical network.

Abstract: The present invention provides a cerebrospinal fluid shunt system that monitors the intracranial pressures over a portion of a monitoring cycle to calculate short intervals of drainage for every monitoring cycle necessary to produce the desired pressure correction. The system operates to significantly reduce the time during which draining occurs allowing tissue surrounding the catheter to rebound from the catheter holes returning to its normal position for a sufficient amount of time to recover its normal shape.

Abstract: The present invention provides an artificial dressing and a use of the artificial dressing for promoting wound healing. The artificial dressing includes a gelatin and a fungal extract.

Abstract: A field effect transistor includes a gate electrode, an insulating layer, a source electrode, a drain electrode, and a channel layer. The insulating layer is located on the surface of the gate electrode, and the channel layer is located on the surface of the insulating layer away from the gate electrode. The source electrode and the drain electrode are spaced apart from each on the surface of the channel layer away from the insulating layer. The source electrode and the drain electrode are one-dimensional structures. The present application further provides a method for making the field effect transistor.

Abstract: The invention provides a copper alloy strip, wherein the copper alloy comprises the following components in percentage by mass: 0.1 wt %-1.0 wt % of Cr, 0.01 wt %-0.2 wt % of Si, 0.01 wt %-1.0 wt % of X and the balance of Cu and inevitable impurities, wherein X is at least one of Fe, Ti, 5 Zr, Ag, Zn and Sn; on a section of the copper alloy strip perpendicular to a rolling direction, the number of second-phase particles having a particle size of 5 nm or below 5 nm is A, the number of second-phase particles having a particle size of 100 nm or above 100 nm is B, and A/B is greater than or equal to 3.

Abstract: A field effect transistor includes a gate electrode, an insulating layer, a source electrode, a drain electrode, and a channel layer. The insulating layer is located on the surface of the gate electrode, and the channel layer is located on the surface of the insulating layer away from the gate electrode. The source electrode and the drain electrode are spaced apart from each on the surface of the channel layer away from the insulating layer. The source electrode and the drain electrode are one-dimensional structures. The present application further provides a method for making the field effect transistor and a method for measuring an interface resistance of the field effect transistor.

Abstract: Embodiments provide for predicting rowhammer attack vulnerability of one or more memory cells of a direct random access memory (DRAM) chip, the DRAM chip including a plurality of memory cells. An example method, determines, for each memory cell of a subset of memory cells of the plurality of memory cells, a leakage time t, a resistance of intrinsic leakage RL based at least in part on the leakage time t, an activation time of an adjacent aggressor row to flip a bit in the memory cell, a resistance of coupling leaking RSW based at least in part on the activation time, and a toggling count. The method identifies, based at least in part on one or more of the RSW, RL, or toggling count, whether the direct random memory access (DRAM) chip is vulnerable to a rowhammer attack.

Abstract: A new set of bench-stable fluoroalkylphosphines that directly convert C—H bonds in pyridine building blocks, drug-like fragments, and pharmaceuticals, into fluoroalkyl derivatives. No pre-installed functional groups or directing motifs are required. The reaction tolerates a variety of sterically and electronically distinct pyridines and is exclusively selective for the 4-position in most cases. The reaction proceeds via initial phosphonium salt formation followed by sp2-sp3 phosphorus ligand-coupling, an underdeveloped manifold for C—C bond formation.

Abstract: The present disclosure discloses the application of fecal microbiological markers in non-invasive identification/early warning of fatty liver in perinatal cows, belonging to the technical field of microorganisms and clinical medicine. The microbiological marker is a combination of one or more of Bifidobacteriumpseudolongum, Prevotellamultisaccharivorax and Lachnospiraceae bacterium.