Abstract: Methods for the manufacture of the therapeutic chemical compound noscapine and noscapine synthesis intermediates comprising contacting a noscapine pathway precursor selected from a first canadine derivative, a first papaveroxine derivative and narcotine hemiacetal with at least one of the enzymes selected from the group CYP82Y1, CYP82X1, AT1, CYP82X2, OMT, CXE1 and NOS.

Abstract: The disclosure provides a method, system, and apparatus for automatically adding ICD code, and a medium. The method for automatically adding an ICD (International Classification of Diseases) code includes: obtaining medical record data; obtaining a vector representation of a respective medical record element through the medical record data; obtaining a vector representation of a respective disease in ICD; obtaining, based on the vector representation of the respective medical record element and the vector representation of the respective disease in ICD, a vector representation of medical record; obtaining, based on the vector representation of the medical record, a respective probability of adding a respective disease code in ICD to the medical record; and obtaining, based on the respective probability, an indication of whether to automatically add the respective ICD code in ICD corresponding to the respective probability to the medical record.

Abstract: The present disclosure describes a treated cellulosic material comprising a cellulosic material having a porous structure defining a plurality of pores, at least a portion of the pores containing a treating agent comprising a polymer, the polymer comprising a polyurethane polymer. The present disclosure further describes a method for preparing a treated cellulosic material comprising providing a cellulosic material; and a first treatment protocol comprising impregnating the cellulosic material with an aqueous dispersion comprising a polymer, the polymer comprising a polyurethane polymer; and a second treatment protocol comprising impregnating the cellulosic material with a modifying agent, the modifying agent comprising a hydrophobic amine.

Abstract: Disclosed are methods for converting a first morphinan alkaloid compound into a second morphinan alkaloid compound in the presence of a neopinone isomerase enzyme under reaction conditions permitting the conversion of the first alkaloid compound into the second alkaloid compound. The first alkaloid compound can be neopinone or neomorphinone. The second alkaloid compound can be codeinone or morphinone. Related compositions are also disclosed.

Abstract: The present disclosure describes a treated cellulosic material comprising a cellulosic material having a porous structure defining a plurality of pores, at least a portion of the pores containing a treating agent comprising a polymer comprising an olefin-carboxylic acid copolymer; and a modifying agent comprising an epoxy.

Abstract: An additive consisting of an active, the active consisting of one or both of tetraacetylethylenediamine or triacetylethylenediamine; and the interfacial polymerization reaction product of a (poly)isocyanate and a polyamine. A method of preparing a water dilution-responsive additive comprising providing an oil phase comprising an active, a solvent, a (poly)isocyanate; providing an aqueous phase comprising water and an emulsifier; mixing the oil phase and the aqueous phase to provide an emulsion; providing a polyamine to the emulsion.

Abstract: The present disclosure describes a treated cellulosic material comprising a cellulosic material having a porous structure defining a plurality of pores, at least a portion of the pores containing a treating agent comprising a polymer comprising an olefin-carboxylic acid copolymer; and a modifying agent comprising an epoxy.

Abstract: A detergent additive comprising an active, the active comprising one or both of tetraacetylethylenediamine or triacetylethylenediamine; and the reaction product of a compound that functions as a Michael donor and a compound that functions as a Michael acceptor; wherein, the compound that functions as a Michael donor is selected from the group consisting of acetoacetate esters, cyanoacetate esters and malonic acid esters; the compound that functions as a Michael acceptor is a multifunctional acrylate; and the weight percent of the tetraacetylethylenediamine in the detergent additive is 10 to 90 percent.

Abstract: A detergent additive comprising an active comprising one or both of tetraacetylethylenediamine, triacetylethylenediamine; and an interpolymer complex, the interpolymer complex comprising both a proton-accepting-(co)polymer and a proton-donating (co)polymer.

Abstract: A method of encapsulating an active comprising preparing a first mixture comprising the active, a compound that functions as a Michael donor, and a compound that functions as a Michael acceptor, preparing a second mixture comprising water and an emulsifier; preparing a reaction mixture by combining the first mixture, the second mixture, and a compound that functions as a Michael catalyst; agitating the reaction mixture; wherein the active has a water solubility of at most 0.5% (w/w) at 25° C.

Abstract: A detergent additive comprising an active, the active comprising one or both of tetraacetylethylenediamine or triacetylethylenediamine; and a copolymer having maleic anhydride-based repeat units and either or both of olefinic or styrenic-based repeat units; and wherein at least a portion of the maleic anhydride-based repeat units are neutralized.

Abstract: A detergent additive comprising an active, the active comprising one or both of tetraacetylethylenediamine and triacetylethylenediamine; and polyvinyl butyral. A method of preparing a detergent additive comprising providing a solvent to a reaction mixture; providing polyvinyl butyral to the reaction mixture; providing an active to the reaction mixture, the active comprising one or both of tetraacetylethylenediamine and triacetylethylenediamine; mixing the reaction mixture; and spray-drying the reaction mixture.

Abstract: An additive comprising an active; the interfacial polymerization reaction product of a (poly)isocyanate and a polyamine; a copolymer having maleic anhydride-based repeat units and either or both of olefinic or styrenic-based repeat units; wherein at least a portion of the maleic anhydride-based repeat units are neutralized. A method of preparing an additive comprising providing an oil phase comprising an active, a solvent, a (poly)isocyanate; providing an aqueous phase comprising water and an emulsifier; mixing the oil phase and the aqueous phase to provide an emulsion; providing a polyamine to the emulsion; providing an aqueous dispersion or solution comprising a copolymer having maleic anhydride-based repeat units and either or both of olefinic or styrenic-based repeat units; wherein at least a portion of the maleic anhydride-based repeat units are neutralized; and cofeeding the emulsion and the aqueous dispersion or solution to a spray dryer.

Abstract: A method and an apparatus for differentially presenting a page are provided, and the method includes: acquiring a page new-old parameter of a page to be presented, and presenting the page based on the page new-old parameter, collecting operation information of the page, and updating the page new-old parameter based on the operation information.

Abstract: Disclosed herein are methods that may be used for the synthesis of benzylisoquinoline alkaloids (BIAs) such as alkaloid morphinan. The methods disclosed can be used to produce thebaine, oripavine, codeine, morphine, oxycodone, hydrocodone, oxymorphone, hydromorphone, naltrexone, naloxone, hydroxycodeinone, neopinone, and/or buprenorphine. Compositions and organisms useful for the synthesis of BIAs, including thebaine synthesis polypeptides, purine permeases, and polynucleotides encoding the same, are provided.

Abstract: Provided is a nursing bed based on heart rate monitoring and voice recognition. The nursing bed includes a nursing bed body, a drive motor and a controller. The nursing bed body includes a bed body fixed part, a bed body movable part and a connector. The bed body fixed part is hinged with a side of the connector, and the bed body moveable part is connected with another side of the connector fixedly. A motor base of the drive motor is installed on the bed body fixed part fixedly, an output shaft of the drive motor is connected with another part of the connector in a meshing manner, and the drive motor is configured to drive the bed body moveable part to swing through the connector.

Abstract: Cyclic ketal compounds provide excellent foam protection when having at least one moiety of a threshold size (comprising 4 or more carbon atoms) pendant from a ketal carbon. The carbons in such moieties may be present in one or more chains. The cyclic ketal compounds of the present invention are compatible with foodstuff manufacturing. In particular, it has been discovered that the cyclic ketal compounds of the present invention exhibit excellent foam control performance in both potato and sugar beet processing systems.

Abstract: The present invention provides a method for simulating magnetic flux leakage based on loop current, the magnetic distribution of a single loop current is obtained by solid angle, then the magnetic field distribution of a semi-infinite solenoid is obtained based on the assumption of arrangement of loop currents in the magnetized specimen, and its equation is given; and the JA hysteresis model is introduced to obtain the distribution of quasi-static magnetic flux leakage field, on the basis of analyzing the relation between the distribution of a loop current on the surface of the defect and the excitation magnetic field, the distribution of quasi-static magnetic flux leakage field is obtained based on the semi-infinite solenoid.

Abstract: A treated cellulosic material comprising a cellulosic material having a porous structure defining a plurality of pores, at least a portion of the pores containing a treating agent comprising a thermoset comprising a cured epoxy resin. The present disclosure further describes a method for preparing a treated cellulosic material comprising (a) providing a cellulosic material; and (b) a first treatment protocol comprising impregnating the cellulosic material with an aqueous dispersion, the aqueous dispersion comprising an epoxy resin and an emulsifying agent.

Abstract: A heating device, an atomizer and an electronic cigarette having the same are disclosed, a heating device includes a shell, with a receiving chamber formed therein; a heating element, received in the receiving chamber to contact with a liquid conductive body; the liquid conductive body, configured for absorbing tobacco liquid and supplying the tobacco liquid to the heating element; the liquid conductive body includes multiple annular liquid conductive layers stacked inside the shell, along an axial direction of the shell; outer diameters of multiple annular conductive layer are equal to an inner diameter of the receiving chamber such that the multiple annular liquid conductive layers are capable of being received in the receiving chamber and abutting against an inner surface of the shell.