Abstract: Disclosed is a 5-methylchromone and the preparation method and application thereof, the 5-methylchromone has the following structure: wherein R1 and R2 are alkyl groups. The substituted chromone has the biological activity of inhibiting tyrosinase. The preparation method uses 3,5-dihydroxytoluene as a raw material, and synthesis of chromones substituted with different groups at 2-C through acylation, esterification, rearrangement and cyclization reactions, etc. The 5-methylchromone is a completely new compound in condition that R1 is —CH2CH2CH3, and R2 is —CH2CH3, or that R1 is —C(CH3)3, and R2 is H. All the compounds have obvious inhibitory activity against tyrosinase, and can be used to prepare tyrosinase inhibitors or whitening agents.

Abstract: A method for measuring aloesin in rat plasma includes: taking the to-be-detected plasma containing aloesin, adding the methanol solution containing the internal standard compound aloeresin D thereinto, performing vortex precipitation, centrifuging, and collecting supernatant as to-be-detected sample; setting liquid chromatogram conditions as follows: carrying out gradient elution by adopting a mobile phase A and a mobile phase B, wherein the mobile phase A is an aqueous solution containing 0.1-1.0 thousandth (v/v) of formic acid, the mobile phase B is methanol; Setting mass spectrometry conditions as follows: using electrospray ion source, using negative ion detection, spray voltage being 4500 V, spray temperature being 550° C.; adopting multiple reaction ion monitoring scan mode, wherein the ion pair used for the quantitative analysis of aloesin is m/z 393.1?272.9, and the ion pair for the internal standard compound aloeresin D is m/z 555.3?144.9. The method improves aloesin detection in plasma.

Abstract: In the technical field of plant medicines, disclosed is the application of aloesin in the preparation of products for preventing or treating obesity. Research has found that aloesin can inhibit lipid accumulation, increase the expression of browning genes UCP1 and PRDM16 and transcription factor C-EBPa, increase the expression and release of specific factor adiponectin, and inhibit the release of non-specific factor IL-1?, indicating that aloesin can mediate the browning of 3T3-L1 adipocytes, and aloesin can be used to prepare products for preventing or treating obesity.

Abstract: A method for measuring aloesin in rat plasma includes: taking the to-be-detected plasma containing aloesin, adding the methanol solution containing the internal standard compound aloeresin D thereinto, performing vortex precipitation, centrifuging, and collecting supernatant as to-be-detected sample; setting liquid chromatogram conditions as follows: carrying out gradient elution by adopting a mobile phase A and a mobile phase B, wherein the mobile phase A is an aqueous solution containing 0.1-1.0 thousandth (v/v) of formic acid, the mobile phase B is methanol; Setting mass spectrometry conditions as follows: using electrospray ion source, using negative ion detection, spray voltage being 4500 V, spray temperature being 550° C.; adopting multiple reaction ion monitoring scan mode, wherein the ion pair used for the quantitative analysis of aloesin is m/z 393.1?272.9, and the ion pair for the internal standard compound aloeresin D is m/z 555.3?144.9. The method improves aloesin detection in plasma.

Abstract: The application provides a display panel motherboard and manufacturing method thereof. The display panel motherboard includes display panel forming areas distributed in an array and a test area adjacent to the display panel forming areas. The display panel motherboard includes an array mother substrate; a light-emitting layer, disposed on a surface of a side of the array mother substrate and located in the display panel forming areas; and a test component, disposed on the surface of the array mother substrate and located in the test area, the test component including a test block including a fluorescent layer, disposed on the surface of the array mother substrate and emitting light upon being irradiated by activation light; a target test layer, disposed on the side of the fluorescent layer facing away from the surface; and a positioning reference portion, disposed at a peripheral side of the target test layer.

Abstract: Disclosed is a 5-methylchromone and the preparation method and application thereof, the 5-methylchromone has the following structure: wherein R1 and R2 are alkyl groups. The substituted chromone has the biological activity of inhibiting tyrosinase. The preparation method uses 3,5-dihydroxytoluene as a raw material, and synthesis of chromones substituted with different groups at 2-C through acylation, esterification, rearrangement and cyclization reactions, etc. The 5-methylchromone is a completely new compound in condition that R1 is —CH2CH2CH3, and R2 is —CH2CH3, or that R1 is —C(CH3)3, and R2 is H. All the compounds have obvious inhibitory activity against tyrosinase, and can be used to prepare tyrosinase inhibitors or whitening agents.

Abstract: An embodiment of the invention provides a data encryption method for an electrical device. The method comprises: generating an identification code corresponding to the electrical device; generating a temporary key according to the identification code; encrypting first data to generate a first secret key according to the temporary key and a first encryption mechanism; and encrypting the first secret key by a second encryption mechanism to generate an encrypted key.

Abstract: An embodiment of the invention provides a data encryption method for an electrical device. The method comprises: generating an identification code corresponding to the electrical device; generating a temporary key according to the identification code; encrypting first data to generate a first secret key according to the temporary key and a first encryption mechanism; and encrypting the first secret key by a second encryption mechanism to generate an encrypted key.