Abstract: Provided is a use of a Galectin-1 inhibitor in preparation of a drug for treating pulmonary fibrosis. Taking silicosis model mice as a subject, administration of a Galectin-1 inhibitor OTX008 to silicosis mice can effectively alleviate the progression of pulmonary fibrosis. Studies have shown that the lung function of mice with silicosis is improved significantly; transcription levels of inflammatory factors Il-1? and Il-6 in the lung tissue of silicosis mice are decreased, concentrations of IL-1? and IL-6 in the alveolar lavage fluid are also decreased, and the infiltration of inflammatory cells is decreased. In the lung tissue of silicosis mice, the transcription levels of fibrosis factors Col-I and Fn-1 are decreased, the collagen-specific amino acid hydroxyproline is decreased, the fibrosis lesions are decreased, and the degree of lesions is alleviated. Therefore, the Galectin-1 inhibitor can be used as a new treatment strategy for pulmonary fibrosis.

Abstract: The present disclosure provides a display substrate, including: a display area and a bonding area positioned on a side of the display area, the bonding area includes a plurality of bonding sub-areas arranged at intervals, the bonding sub-areas are arranged along a direction in which an edge of the display area extends and configured for bonding a chip-on-film, where a first antistatic layer is further arranged on the bonding area, at least a part of the first antistatic layer is positioned between adjacent ones of the bonding sub-areas, and the first antistatic layer is electrically coupled to a reference signal terminal. The present disclosure further provides a display device.

Abstract: The Bacillus velezensis M173 was deposited with the Guangdong Microbial Culture Collection Center with a deposit number of GDMCC No. 61434. After being prepared into a seed-coating agent, Bacillus velezensis M173 can promote the growth and germination of plants and significantly improve the control effect on pathogens. Moreover, Bacillus velezensis M173 can relieve the condition of dead seedlings of crops at seedling stage after being applied to the crops. In particular, both pot experiments and field experiments prove that the Bacillus velezensis M173 of the present invention has a significant control effect on fungal and bacterial diseases, in particular, bacterial wilt and stem rot. Therefore, the Bacillus velezensis M173 of the present invention has broad application prospects.

Abstract: A composite interlaced yarn is a filament subjected to an interlacing process, wherein the filament is a multifilament, and the composite interlaced yarn includes a plurality of continuous circulation units in a longitudinal length; each circulation unit includes a splitting part I, an interlacing part I, a splitting part II and an interlacing part II connected in sequence; an interlacing fastness of the interlacing part I is different from an interlacing fastness of the interlacing part II. An interlacing method for the composite interlaced yarn includes: the multifilament that is not subjected to the interlacing process sequentially adjusting a pre-tension by a tensioner, passing through a yarn path of a jet, and winding by a winding roller, so as to obtain the composite interlaced yarn, wherein a jet hole I and a jet hole II are formed in the jet.

Abstract: A wheeled carrying apparatus includes a handle frame rotatable relative to a standing frame between a first and a second position, a wheel mount pivotally connected with the standing frame, a wheel mount latch adapted to lock and unlock the wheel mount with respect to the standing frame, an actuating assembly coupling the wheel mount latch to the handle frame so that the wheel mount latch is movable to engage and disengage the wheel mount in response to a rotation of the handle frame, and a release mechanism including an operating part that is coupled to the actuating assembly via a cable assembly, the operating part being operable to cause the wheel mount latch to disengage from the wheel mount when the handle frame is in the first position.

Abstract: The present disclosure belongs to the technical field of microorganisms, and specifically relates to a non-toxin-producing Aspergillus flavus strain, a microbial inoculant, a preparation, and use. The present disclosure provides a non-toxin-producing Aspergillus flavus strain EXY1A109 with a deposit number of CCTCC No: M20221465. The strain can effectively inhibit the production of aflatoxin B1, aflatoxin B2, aflatoxin G1, and aflatoxin G2 by a toxin-producing Aspergillus flavus strain. The results of examples show that when an Aspergillus flavus strain EXY1A109 spore suspension and a strain CGMCC 3.4408 spore suspension are mixed in an equal volume, the Aspergillus flavus strain EXY1A109 spore suspension and the strain CGMCC 3.4408 spore suspension each have a concentration of 1×106, and the strain EXY1A109 has a toxin-producing inhibition rate of 99.71% against the strain CGMCC 3.4408. This Aspergillus flavus strain shows a desirable application effect.

Abstract: The present application relates to lipid nanoparticles having a diameter above certain value, as well as the preparation and uses of such compositions. Lipid nanoparticles presented in the application generally have a diameter of at least 160 nm. Such lipid nanoparticles are useful in the delivery of therapeutic agents, such as nucleic acids, in vivo to none-hepatic organs (e.g., lung) for the treatment or prevention of certain diseases or disorders.

Abstract: Disclosed is separation process of valuable metals from copper anode slime based on oxidation potential modulation, belonging to the technical field of industrial solid waste resource utilization. The differences in redox properties of different metal elements are used to precisely regulate the oxidation potential and acidity of the leaching solution by regulating the amount of oxidizing agent and acid added, so as to selectively and graded leaching and separating the copper (Cu), selenium (Se), tellurium (Te), and silver (Ag) metal elements, and the oxidants used are substances such as H2O2, O2 and O3.

Abstract: The invention relates to various aspects of a ?-LED or a ?-LED array for augmented reality or lighting applications, in particular in the automotive field. The ?-LED is characterized by particularly small dimensions in the range of a few ?m.

Abstract: A nucleic acid aptamer specifically recognizing soluble ST2 protein and its application, belonging to the field of variation or genetic engineering, are described. The technical problem addressed includes how to specifically detect sST2 protein. In order to address this technical problem, nucleic acid aptamers of single-stranded DNA with nucleotide sequences are shown in SEQ ID No. 1-10, respectively. SELEX technology, combined with high-throughput sequencing technology and bioinformatics analysis, reduces the rounds of screening and obtains candidate nucleic acid aptamers, and further analyzes its affinity and specificity to obtain a nucleic acid aptamer that specifically recognizes sST2 protein. The nucleic acid aptamer has the characteristics of high specificity, high stability, convenient synthesis, and easy labeling of functional groups, and the like, and may be used for the detection of sST2 protein and the preparation of biosensors, diagnosis and prognosis of cardiovascular diseases and other products.

Abstract: This disclosure relates to biodegradable core-shell microcapsule compositions wherein the microcapsule shell contains a polymer formed with a biobased epoxide and a polyamine. This disclosure also relates to a method of preparing such biodegradable core-shell microcapsules. This disclosure also relates to consumer products containing such biodegradable core-shell microcapsules.

Abstract: A wheeled carrying apparatus includes a standing frame, a handle frame, a wheel mount, a locking assembly and a release mechanism. The handle frame is rotatable between a first and a second position. The wheel mount carries a wheel and is rotatable relative to the standing frame for changing an orientation of the wheel axis. The locking assembly is configured to rotationally lock the wheel mount with respect to the standing frame, and configured to unlock the wheel mount so that the wheel mount is rotatable relative to the standing frame for changing an orientation of the wheel axis. The release mechanism includes a first portion provided on the standing frame and coupled to the locking mechanism, and a second portion carried with the handle frame, the second portion being movable along with the handle frame toward and away from the first portion during rotation of the handle frame between the first position and the second position.

Abstract: A mounting structure for a pickup bed cover includes two mounting rods and a folding cover plate. The two mounting rods are in parallel, and the cover plate is fixed with the mounting rods together. The mounting structure for the pickup bed cover further includes a supporting rod, a first hinge seat and a second hinge seat. The first hinge seat is arranged on one of the mounting rods and the second hinge seat is arranged on the cover plate, one end of the supporting rod is fixedly hinged with the first hinge seat, and the other end of the supporting rod is detachably hinged with the second hinge seat. With one end of the supporting rod being fixedly hinged and the other end of the supporting rod being detachably hinged, a stable mounting structure is obtained and it is more convenient to mount.

Abstract: A wheeled carrying apparatus includes a standing frame, a handle frame, a wheel mount, a locking assembly and a release mechanism. The handle frame is rotatable between a first and a second position. The wheel mount carries a wheel and is rotatable relative to the standing frame for changing an orientation of the wheel axis. The locking assembly is configured to rotationally lock the wheel mount with respect to the standing frame, and configured to unlock the wheel mount so that the wheel mount is rotatable relative to the standing frame for changing an orientation of the wheel axis. The release mechanism includes a first portion provided on the standing frame and coupled to the locking mechanism, and a second portion carried with the handle frame, the second portion being movable along with the handle frame toward and away from the first portion during rotation of the handle frame.

Abstract: In an embodiment a method includes providing a growth substrate layer, depositing a first doped [(AlxGa1-x)yIn1-y]zP1-z carrier transport layer on the substrate layer with x in a range of [0.5;1] along a growth direction, and depositing an active region along the growth direction, the active region for generating radiation and comprising a plurality of alternating [(AlaGa1-a)bIn1-b]cP1-c quantum well layers and [(AldGa1-d)eIn1-e]fP1-f barrier layers, wherein a is in a range of [0;0.5] and d is in a range of [0.45;1.0], wherein depositing of at least one of the barrier layer and/or the quantum well layer comprises doping with a dopant having a concentration in a range of 1e15 atoms/cm3 to 5e17 atoms/cm3, wherein the dopant is selected from at least one of the group consisting of Mg, Zn, Te and Si or depositing a second doped carrier transport [(AlxGa1-x)yIn1-y]zP1-z layer with x in a range of [0.45;1] along the growth direction.

Abstract: Provided are a camera multi-line time-division exposure processing method and a system. N sensor lines correspond to the n light sources in a one-to-one correspondence. The sensor lines is configured to respectively collect image data of an object moving through the camera's field of view along one direction under the corresponding light sources. The method includes: obtaining a trigger signal to trigger at one time the n light sources to turn on and off sequentially, collecting image data of the object exposed under a turned-on light source, and extracting image data of the object obtained by one sensor line corresponding to the turned-on light source as valid data; splicing all the valid data of the same portion of the object to obtain a spliced image under different light sources; and cyclically outputting the spliced image to obtain a complete image of the object.

Abstract: Novel lithographic compositions for use as an EUV underlayer are disclosed. The invention includes methods of fabricating microelectronics structures using those compositions as well as structures formed by those methods. The method involves utilizing an underlayer immediately below the photoresist layer. The underlayer can either be directly applied to the substrate, or it can be applied to any intermediate layer(s) that may be applied to the substrate. The preferred underlayers are formed from spin-coatable, monomeric, oligomeric, and/or polymeric compositions and exhibit uniform thicknesses and low roughness. The disclosed method enables a 14/28 nm pattern using EUV lithography and better depth of focus (DOF) than standard EUV underlayers.