Patents by Inventor Xue-Rong Zhou

Xue-Rong Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230416186
    Abstract: The present invention relates to lipid comprising docosapentaenoic acid and/or docosahexaenoic acid wherein the docosapentaenoic acid and/or docosahexaenoic acid may be preferentially esterified at the sn-2 position of triacylglycerol, and processes for producing and using the lipid.
    Type: Application
    Filed: June 14, 2023
    Publication date: December 28, 2023
    Applicants: Commonwealth Scientific and Industrial Research Organisation, Grains Research and Development Corporation, Nuseed Nutritional Australia Pty Ltd
    Inventors: James Robertson Petrie, Surinder Pal Singh, Pushkar Shrestha, Jason Timothy McAllister, Robert Charles de Feyter, Malcolm David Devine, Xue-Rong Zhou
  • Patent number: 11718577
    Abstract: The present invention relates to lipid comprising docosapentaenoic acid and/or docosahexaenoic acid wherein the docosapentaenoic acid and/or docosahexaenoic acid may be preferentially esterified at the sn-2 position of triacylglycerol, and processes for producing and using the lipid.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: August 8, 2023
    Assignees: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, GRAINS RESEARCH AND DEVELOPMENT CORPORATION, NUSEED NUTRITIONAL AUSTRALIA PTY LTD
    Inventors: James Robertson Petrie, Surinder Pal Singh, Pushkar Shrestha, Jason Timothy McAllister, Robert Charles de Feyter, Malcolm David Devine, Xue-Rong Zhou
  • Patent number: 11597953
    Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: March 7, 2023
    Assignee: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Surinder Pal Singh, Stanley Suresh Robert, Peter David Nichols, Susan Irene Ellis Blackburn, Xue-Rong Zhou, James Robertson Petrie, Allan Graham Green
  • Publication number: 20220346340
    Abstract: The present embodiments provide a novel DPA-producing Brassica juncea (DPA juncea) line designated as NUBJ1207. The embodiments also provide the seeds, the plants, and the plant parts (including DNA) of DPA juncea line NUBJ1207, as well as to methods for producing a Brassica plant produced by crossing DPA juncea line NUBJ1207 with itself or another Brassica line. These embodiments also provide methods for producing a DPA-producing Brassica plant containing in its genetic material one or more transgenes, and to the transgenic plants and plant parts produced by those methods. These embodiments further provide DPA production lines or breeding lines and plant parts derived from DPA juncea line NUBJ1207, to methods for producing canola lines or plant parts derived from line NUBJ1207, and to the DPA-producing Brassica plants, varieties, and their parts derived from use of those methods.
    Type: Application
    Filed: August 26, 2020
    Publication date: November 3, 2022
    Inventors: GREG BUZZA, SRINIVAS BELIDE, MALCOLM DEVINE, WENXIANG GAO, NELSON GORORO, ANTONIO LEONFORTE, JASON MCALLISTER, JAMES PETRIE, PUSHKAR SHRESTHA, SURINDER SINGH, XUE-RONG ZHOU
  • Publication number: 20220186269
    Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desatorase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.
    Type: Application
    Filed: November 3, 2021
    Publication date: June 16, 2022
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Surinder Pal Singh, Stanley Suresh Robert, Peter David Nichols, Susan Irene Ellis Blackburn, Xue-Rong Zhou, James Robertson Petrie, Allan Graham Green
  • Patent number: 11220698
    Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: January 11, 2022
    Assignee: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Surinder Pal Singh, Stanley Suresh Robert, Peter David Nichols, Susan Irene Ellis Blackburn, Xue-Rong Zhou, James Robertson Petrie, Allan Graham Green
  • Patent number: 11166479
    Abstract: The present invention relates to feedstuffs for use in aquaculture, as well as methods for producing said feedstuffs. The invention also provides methods for rearing fish and/or crustaceans. In particular, the present invention provides a method of rearing a fish or crustacean, the method comprising feeding the fish or crustacean a feedstuff comprising lipid, the fatty acid of said lipid comprising at least 5.5% (w/w) stearidonic acid (SDA).
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: November 9, 2021
    Assignee: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Matthew Robert Miller, Christopher Guy Carter, Peter David Nichols, Surinder Pal Singh, Xue-Rong Zhou, Allan Graham Green
  • Patent number: 11124737
    Abstract: The present invention relates to extracted lipid with high levels, for example 90% to 95% by weight, oleic acid. The present invention also provides genetically modified plants, particularly oilseeds such as safflower, which can used to produce the lipid. Furthermore, provided are methods for genotyping and selecting plants which can be used to produce the lipid.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: September 21, 2021
    Assignee: COMMONWEALTH SCIENTIFIC ANDN INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Craig Christopher Wood, Qing Liu, Xue-Rong Zhou, Allan Green, Surinder Pal Singh, Shijiang Cao
  • Publication number: 20210263041
    Abstract: The embodiments herein provide methods to analyze the in vitro stability of recalcitrant or membrane-bound proteins in simulated gastric fluid (SGF) comprising the proteolytic enzyme, pepsin, and in combination with a novel pepsin-trypsin assay employing state-of-the-art mass spectrometric approaches, such as LC-MS/MS, to monitor the precise degradation products. The extent of protein digestion can be evaluated by the appearance of peptic products and the disappearance of tryptic peptide products (as a proxy for intact protein). The embodiments herein also provide methods for protein quantitation using high-sensitivity LC-MRM-MS quantification. The methods embodied herein are particularly useful in charactering proteins produced in transgenic plants, such as canola genetically engineered to produce long chain omega-3 polyunsaturated fatty acids.
    Type: Application
    Filed: March 8, 2018
    Publication date: August 26, 2021
    Applicants: Nuseed Pty Ltd, COMMONWEALTH SCIENTIFIC & INDUSTRIAL RESEARCH ORG
    Inventors: Susan MacIntosh, Michelle Colgrave, Keren Byrne, Jo Caine, Xue-Rong Zhou
  • Publication number: 20210246097
    Abstract: The present invention relates to lipid comprising docosapentaenoic acid and/or docosahexaenoic acid wherein the docosapentaenoic acid and/or docosahexaenoic acid may be preferentially esterified at the sn-2 position of triacylglycerol, and processes for producing and using the lipid.
    Type: Application
    Filed: October 5, 2020
    Publication date: August 12, 2021
    Applicants: Commonwealth Scientific and Industrial Research Organisation, Grains Research and Development Corporation, Nuseed Pty Ltd.
    Inventors: James Robertson Petrie, Surinder Pal Singh, Pushkar Shrestha, Jason Timothy McAllister, Robert Charles de Feyter, Malcolm David Devine, Xue-Rong Zhou
  • Publication number: 20200392547
    Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.
    Type: Application
    Filed: May 7, 2020
    Publication date: December 17, 2020
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Surinder Pal Singh, Stanley Suresh Robert, Peter David Nichols, Susan Irene Ellis Blackburn, Xue-Rong Zhou, James Robertson Petrie, Allan Graham Green
  • Publication number: 20200385822
    Abstract: The present invention relates generally to the field of recombinant fatty acid synthesis, particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular, the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome, such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ.
    Type: Application
    Filed: April 28, 2020
    Publication date: December 10, 2020
    Applicants: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, GRAINS RESEARCH AND DEVELOPMENT CORPORATION
    Inventors: James Robertson Petrie, Anne Maree Mackenzie, Qing Liu, Pushkar Shrestha, Peter David Nichols, Susan Irene Ellis Blackburn, Maged Peter Mansour, Stanley Suresh Robert, Dion Matthew Frederick Frampton, Xue-Rong Zhou, Surinder Pal Singh, Craig Christopher Wood
  • Patent number: 10793507
    Abstract: The present invention relates to lipid comprising docosapentaenoic acid and/or docosahexaenoic acid preferentially esterified at the sn-2 position of triacylglycerol, and processes for producing and using the lipid.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: October 6, 2020
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Grains Research and Development Corporation, Nuseed Pty Ltd.
    Inventors: James Robertson Petrie, Surinder Pal Singh, Pushkar Shrestha, Jason Timothy McAllister, Robert Charles de Feyter, Malcolm David Devine, Xue-Rong Zhou
  • Patent number: 10781463
    Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: September 22, 2020
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Surinder Pal Singh, Stanley Suresh Robert, Peter David Nichols, Susan Irene Ellis Blackburn, Xue-Rong Zhou, James Robertson Petrie, Allan Graham Green
  • Patent number: 10648046
    Abstract: The present invention relates generally to the field of recombinant fatty acid synthesis, particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular, the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome, such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: May 12, 2020
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Grains Research and Development Corporation
    Inventors: James Robertson Petrie, Anne Maree Mackenzie, Qing Liu, Pushkar Shrestha, Peter David Nichols, Susan Irene Ellis Blackburn, Maged Peter Mansour, Stanley Suresh Robert, Dion Matthew Frederick Frampton, Xue-Rong Zhou, Surinder Pal Singh, Craig Christopher Wood
  • Publication number: 20200115725
    Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desatorase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.
    Type: Application
    Filed: August 21, 2019
    Publication date: April 16, 2020
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Surinder Pal Singh, Stanley Suresh Robert, Peter David Nichols, Susan Irene Ellis Blackburn, Xue-Rong Zhou, James Robertson Petrie, Allan Graham Green
  • Patent number: 10513717
    Abstract: The present invention relates to enzymes which possess desaturase, conjugase, epoxidase and/or hydroxylase activity that can be used in methods of synthesizing fatty acids.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: December 24, 2019
    Assignees: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, GRAINS RESEARCH AND DEVELOPMENT CORPORATION
    Inventors: Katherine Damcevski, Karen Glover, Allan Green, Victoria S. Haritos, Irene Horne, Surinder Pal Singh, Craig C. Wood, Xue-Rong Zhou
  • Publication number: 20190330558
    Abstract: The present invention relates to extracted lipid with high levels, for example 90% to 95% by weight, oleic acid. The present invention also provides genetically modified plants, particularly oilseeds such as safflower, which can used to produce the lipid. Furthermore, provided are methods for genotyping and selecting plants which can be used to produce the lipid.
    Type: Application
    Filed: May 14, 2019
    Publication date: October 31, 2019
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Craig Christopher WOOD, Qing LIU, Xue-Rong ZHOU, Allan GREEN, Surinder Pal SINGH, Shijiang CAO
  • Patent number: 10323209
    Abstract: The present invention relates to extracted lipid with high levels, for example 90% to 95% by weight, oleic acid. The present invention also provides genetically modified plants, particularly oilseeds such as safflower, which can used to produce the lipid. Furthermore, provided are methods for genotyping and selecting plants which can be used to produce the lipid.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: June 18, 2019
    Assignee: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Craig Christopher Wood, Qing Liu, Xue-Rong Zhou, Allan Green, Surinder Pal Singh, Shijiang Cao
  • Publication number: 20180354888
    Abstract: The present invention relates to lipid comprising docosapentaenoic acid and/or docosahexaenoic acid preferentially esterified at the sn-2 position of triacylglycerol, and processes for producing and using the lipid.
    Type: Application
    Filed: May 17, 2018
    Publication date: December 13, 2018
    Inventors: James Robertson Petrie, Surinder Pal Singh, Pushkar Shrestha, Jason Timothy McAllister, Robert Charles de Feyter, Malcolm David Devine, Xue-Rong Zhou