Patents by Inventor Xue Zhong
Xue Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11365250Abstract: The present disclosure generally relates to compositions and methods for cancer immunotherapy, as well as hematopoietic recovery following cancer treatment such as chemotherapy or irradiation.Type: GrantFiled: November 29, 2018Date of Patent: June 21, 2022Assignee: The Board of Regents of The University of Texas SystemInventors: Bruce Beutler, Evan Nair-Gill, Xue Zhong, Jinglei Zhang, Pingping Wang
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Publication number: 20220162303Abstract: The present disclosure generally relates to compositions and methods for cancer immunotherapy, as well as hematopoietic recovery following cancer treatment such as chemotherapy or irradiation.Type: ApplicationFiled: February 11, 2022Publication date: May 26, 2022Inventors: Bruce Beutler, Evan Nair-Gill, Xue Zhong, Jinglei Zhang, Pingping Wang
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Patent number: 11139618Abstract: An electrical module is electrically conducted with an electronic component, and includes multiple conductors having a first row of conductors arranged in a left-right direction and an insulating body fixing the first row of conductors. Each conductor has a contact portion in contact with the electronic component. A distance between each two adjacent contact portions of the conductors in the left-right direction is defined as a contact interval. The first row of conductors have at least one pair of signal conductors and at least two ground conductors. Each two adjacent sides of the pair of signal conductors has one ground conductor. The contact interval from one signal conductor to its adjacent ground conductor is defined as a first contact interval. The contact interval from the other signal conductor to its adjacent ground conductor is defined as a second contact interval. The first and second contact intervals are not equal.Type: GrantFiled: June 11, 2020Date of Patent: October 5, 2021Assignee: LOTES CO., LTDInventors: Qi Xiao Yang, Yong Fu Wang, Wei Xue Zhong, Biao Zhang, Jia Xu Yin
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Publication number: 20210269519Abstract: The present disclosure generally relates to a method for providing an immune suppressive therapy, in particular by inhibiting LMBR1L (limb region 1 like) in a subject in need thereof. Also, provided herein are compositions and kits that can be used in such methods.Type: ApplicationFiled: June 26, 2019Publication date: September 2, 2021Inventors: Bruce Beutler, Jin Huk Choi, Xue Zhong, Evan Nair-Gill
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Publication number: 20210159642Abstract: An electrical module is electrically conducted with an electronic component, and includes multiple conductors having a first row of conductors arranged in a left-right direction and an insulating body fixing the first row of conductors. Each conductor has a contact portion in contact with the electronic component. A distance between each two adjacent contact portions of the conductors in the left-right direction is defined as a contact interval. The first row of conductors have at least one pair of signal conductors and at least two ground conductors. Each two adjacent sides of the pair of signal conductors has one ground conductor. The contact interval from one signal conductor to its adjacent ground conductor is defined as a first contact interval. The contact interval from the other signal conductor to its adjacent ground conductor is defined as a second contact interval. The first and second contact intervals are not equal.Type: ApplicationFiled: June 11, 2020Publication date: May 27, 2021Inventors: Qi Xiao Yang, Yong Fu Wang, Wei Xue Zhong, Biao Zhang, Jia Xu Yin
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Patent number: 10944192Abstract: An electrical connector is used to be electrically connected to a mating component. The electrical connector includes a body having an insertion slot for the mating component to insert therein along a mating direction, and two side walls located at two opposite sides of the insertion slot and extending along an elongated direction perpendicular to the mating direction. A retainer is provided at one end of the body along the elongated direction to buckle with the mating component. Multiple terminals are provided on the two side walls, protruding into the insertion slot to mate with the mating component. A metal member is provided on the body and correspondingly covering one of the side walls. The metal member is provided with at least one through slot provided obliquely relative to the mating direction and adjacent to the retainer in the elongated direction.Type: GrantFiled: November 26, 2019Date of Patent: March 9, 2021Assignee: LOTES CO., LTDInventors: Wei Xue Zhong, Biao Zhang
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Publication number: 20200385459Abstract: The present disclosure generally relates to compositions and methods for cancer immunotherapy, as well as hematopoietic recovery following cancer treatment such as chemotherapy or irradiation.Type: ApplicationFiled: November 29, 2018Publication date: December 10, 2020Inventors: Bruce Beutler, Evan Nair-Gill, Xue Zhong, Jinglei Zhang, Pingping Wang
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Publication number: 20200248203Abstract: Disclosed are compositions and methods that useful in the treatment and/or prevention of hearing loss caused by genetic mutation of the TMPRSS3 gene or the LOXHD1 gene. The compositions and methods disclosed herein use adeno-associated viral (AAV) vector gene delivery of TRMPSS3 or LOXHD1 into the inner ear to restore activity of the TMPRSS3 gene or the LOXHD1 gene, respectively, promote hair cell survival and restore hearing in patients suffering from hearing loss.Type: ApplicationFiled: March 16, 2018Publication date: August 6, 2020Inventors: Hinrich Staecker, Xue Zhong Liu, Zheng-Yi Chen, Caesar James Ayala
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Publication number: 20200176904Abstract: An electrical connector is used to be electrically connected to a mating component. The electrical connector includes a body having an insertion slot for the mating component to insert therein along a mating direction, and two side walls located at two opposite sides of the insertion slot and extending along an elongated direction perpendicular to the mating direction. A retainer is provided at one end of the body along the elongated direction to buckle with the mating component. Multiple terminals are provided on the two side walls, protruding into the insertion slot to mate with the mating component. A metal member is provided on the body and correspondingly covering one of the side walls. The metal member is provided with at least one through slot provided obliquely relative to the mating direction and adjacent to the retainer in the elongated direction.Type: ApplicationFiled: November 26, 2019Publication date: June 4, 2020Inventors: Wei Xue Zhong, Biao Zhang
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Publication number: 20190247511Abstract: Described herein are compositions and methods for treating or preventing an injury associated with transplant. Specifically, the disclosure provides a composition for treating or preventing an injury associated with transplantation, comprising (a) a targeted inhibitor molecule wherein the targeted inhibitor molecule comprises a targeting portion and an inhibitor portion, wherein the molecule inhibits complement pathways, and (b) a sub-therapeutic dose of an immunosuppressant agent. Further provided are methods of treating or preventing an injury associated with transplantation with activated complement by using the compositions.Type: ApplicationFiled: October 17, 2017Publication date: August 15, 2019Inventors: Stephen TOMLINSON, Carl ATKINSON, Xue-Zhong YU
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Patent number: 9182352Abstract: A method for detecting crude oil or gas in a drilling sample includes introducing a drilling sample into a sample solution containing nano particles, illuminating the sample solution comprising the drilling sample and the nano particles by a laser beam, collecting light scattered by the drilling sample and the nano particles in the sample solution, obtaining a Raman spectrum from the light scattered by the drilling sample and the nano particles in the sample solution, identifying, in the Raman spectrum, a spectral signature associated with a substance around a predetermined Raman shift, and detecting targeted chemicals correlated with crude oil or gas existence underground from where the drilling sample, based on the spectral signature of the substance in the Raman spectrum.Type: GrantFiled: October 10, 2013Date of Patent: November 10, 2015Assignee: OptoTrace (SuZhou) Technologies, Inc.Inventors: Hong Wang, Xun Guo, Xue Zhong, Dong Zhang, Chunwei Liu, Hao Zhou, Tianrui Ni
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Patent number: 8699019Abstract: A method for inspecting an edible oil includes obtaining a first Raman spectrum from an edible oil sample, discovering an unhealthy, unsanitary, unsafe, or adulterated content in the edible oil sample in part by the intensity level of the fluorescence background in the first Raman spectrum, introducing the edible oil sample to nano-scale surface structures to allow molecules of the edible oil sample to be adsorbed to the nano-scale surface structures, illuminating the edible oil sample and the nano-scale surface structures by a laser beam, obtaining a second Raman spectrum from light scattered by molecules of the edible oil sample adsorbed to the nano-scale surface structures, and identifying the unhealthy, unsanitary, or unsafe content in the edible oil sample using one or more first spectral signatures in the second Raman spectrum.Type: GrantFiled: April 9, 2012Date of Patent: April 15, 2014Assignee: OptoTrace (Suzhou) Technologies, Inc.Inventors: Hong Wang, Xun Guo, Chunwei Liu, Hao Zhou, Ning Ma, Xue Zhong
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Publication number: 20140043607Abstract: A method for detecting crude oil or gas in a drilling sample includes introducing a drilling sample into a sample solution containing nano particles, illuminating the sample solution comprising the drilling sample and the nano particles by a laser beam, collecting light scattered by the drilling sample and the nano particles in the sample solution, obtaining a Raman spectrum from the light scattered by the drilling sample and the nano particles in the sample solution, identifying, in the Raman spectrum, a spectral signature associated with a substance around a predetermined Raman shift, and detecting targeted chemicals correlated with crude oil or gas existence underground from where the drilling sample, based on the spectral signature of the substance in the Raman spectrum.Type: ApplicationFiled: October 10, 2013Publication date: February 13, 2014Applicant: Opto Trace (Suzhou) Technologies, Inc.Inventors: Hong Wang, Xun Guo, Xue Zhong, Dong Zhang, Chunwei Liu, Hao Zhou, Tianrui Ni
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Publication number: 20130017298Abstract: A method for inspecting an edible oil includes obtaining a first Raman spectrum from an edible oil sample, discovering an unhealthy, unsanitary, unsafe, or adulterated content in the edible oil sample in part by the intensity level of the fluorescence background in the first Raman spectrum, introducing the edible oil sample to nano-scale surface structures to allow molecules of the edible oil sample to be adsorbed to the nano-scale surface structures, illuminating the edible oil sample and the nano-scale surface structures by a laser beam, obtaining a second Raman spectrum from light scattered by molecules of the edible oil sample adsorbed to the nano-scale surface structures, and identifying the unhealthy, unsanitary, or unsafe content in the edible oil sample using one or more first spectral signatures in the second Raman spectrum.Type: ApplicationFiled: April 9, 2012Publication date: January 17, 2013Inventors: Hong Wang, Xun Guo, Chunwei Liu, Hao Zhou, Ning Ma, Xue Zhong
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Publication number: 20020006403Abstract: The present invention provides methods for suppressing, reducing or even reversing an immune response. More particularly it concerns anti-CD28 monoclonal antibody compositions and methods for preventing graft-versus-host disease (GVHD), transplant tissue rejection, and treating autoimmune diseases and the like. In particular embodiments, a method of inhibiting an immune response comprises administering an effective amount of a purified anti-CD28 antibody preparation to a subject, wherein the preparation modulates the CD28 receptor thereby inhibiting an immune response.Type: ApplicationFiled: December 14, 2000Publication date: January 17, 2002Inventors: Xue-Zhong Yu, Claudio Anasetti