Patents by Inventor Xueer ZHAO

Xueer ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combined prophylactic and therapeutic vaccines
    Patent number: 12161708
    Abstract: The present invention relates to an immunogenic polypeptide comprising (i) a B-cell epitope, (ii) a T-cell epitope, and (iii) a scaffold polypeptide, wherein said scaffold polypeptide is a thioredoxin polypeptide. The present invention further relates to said immunogenic polypeptide for use in medicine and for use in treating and/or preventing inappropriate proliferation of cells and/or infection with an infectious agent, preferably HPV infection, as well as to polypeptides and vectors encoding said immunogenic polypeptide.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: December 10, 2024
    Assignee: Deutsches Krebsforschungszentrum
    Inventors: Martin Müller, Simone Ottonello, Xueer Zhao
  • Cutaneous papilloma virus vaccine
    Patent number: 11547753
    Abstract: The present invention relates to an immunogenic polypeptide comprising a multitude of papillomavirus (PV) L2 N-terminal peptides corresponding to amino acids 20 to 50 of the L2 polypeptide of HPV16, wherein said HPV L2 N-terminal peptides are L2 N-terminal peptides from at least four different cutaneous HPV genotypes; and to the aforesaid immunogenic polypeptide for use in medicine and for use in vaccination of a subject against cutaneous HPV infection and/or mucosal HPV infection. The present invention further relates to a polynucleotide encoding the aforesaid immunogenic polypeptide and to vectors, host cells, methods for producing an antibody, as well as antibodies related thereto.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: January 10, 2023
    Assignee: Deutsches Krebsforschungszentrum
    Inventors: Martin Müller, Simone Ottonello, Angelo Bolchi, Filipe Mariz, Xueer Zhao, Kathrin Balz
  • COMBINED PROPHYLACTIC AND THERAPEUTIC VACCINES
    Publication number: 20210228702
    Abstract: The present invention relates to an immunogenic polypeptide comprising (i) a B-cell epitope, (ii) a T-cell epitope, and (iii) a scaffold polypeptide, wherein said scaffold polypeptide is a thioredoxin polypeptide. The present invention further relates to said immunogenic polypeptide for use in medicine and for use in treating and/or preventing inappropriate proliferation of cells and/or infection with an infectious agent, preferably HPV infection, as well as to polypeptides and vectors encoding said immunogenic polypeptide.
    Type: Application
    Filed: May 29, 2019
    Publication date: July 29, 2021
    Inventors: Martin Müller, Simone Ottonello, Xueer Zhao
  • CUTANEOUS PAPILLOMA VIRUS VACCINE
    Publication number: 20200261563
    Abstract: The present invention relates to an immunogenic polypeptide comprising a multitude of papillomavirus (PV) L2 N-terminal peptides corresponding to amino acids 20 to 50 of the L2 polypeptide of HPV16, wherein said HPV L2 N-terminal peptides are L2 N-terminal peptides from at least four different cutaneous HPV genotypes; and to the aforesaid immunogenic polypeptide for use in medicine and for use in vaccination of a subject against cutaneous HPV infection and/or mucosal HPV infection. The present invention further relates to a polynucleotide encoding the aforesaid immunogenic polypeptide and to vectors, host cells, methods for producing an antibody, as well as antibodies related thereto.
    Type: Application
    Filed: October 1, 2018
    Publication date: August 20, 2020
    Applicant: Deutsches Krebsforschungszentrum
    Inventors: Martin MÜLLER, Simone OTTONELLO, Angeio BOLCHI, Filipe MARIZ, Xueer ZHAO, Kathrin BALZ