Patents by Inventor Xuefei QIU

Xuefei QIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY-DRUG CONJUGATE, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20220233708
    Abstract: Disclosed are an antibody-drug conjugate (ADC), an intermediate thereof, a preparation method therefor and an application thereof. The present invention provides an ADC. A structural general formula thereof is Ab-(L3-L2-L1-D)m. The ADC has better biological activity, stability, and uniformity, has reduced toxic and side effects, and has a faster release rate of enzyme cutting in tumor cells. The use of the novel ADC can achieve a wide application of a cytotoxic drug particularly camptothecin in the field of ADCs in treating tumor patients resistant to microtubule ADC.
    Type: Application
    Filed: June 5, 2020
    Publication date: July 28, 2022
    Inventors: Bin BAO, Qingsong GUO, Bei GAO, Yifan ZHANG, Xuefei QIU, Tong YANG, Yijun SHEN, Wenbo ZHANG, Wei LV, Lei WANG