Patents by Inventor Xueguang Jin

Xueguang Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Determining the Likelihood of Survival and for Predicting Likelihood of Metastasis in Cancer Patients
    Publication number: 20230062274
    Abstract: The present invention relates generally to methods of accurately quantifying HER2 and/or p95 expression in subjects with a HER2 positive cancer and indicating the risk of brain relapse in such patients.
    Type: Application
    Filed: June 30, 2022
    Publication date: March 2, 2023
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Weidong Huang, Jodi Weidler, Jeff Sperinde, Mojgan Haddad, Michael Bates, John William Winslow, Xueguang Jin, Gerald J. Wallweber, Jennifer W. Cook, Gundo Diedrich, Laurie Goodman, Ali Mukherjee, Gordon Parry, Stephen J. Williams
  • Methods for determining the likelihood of survival and for predicting likelihood of metastasis in cancer patients
    Patent number: 11579148
    Abstract: The present invention relates generally to methods of accurately quantifying HER2 and/or p95 expression in subjects with a HER2 positive cancer and indicating the risk of brain relapse in such patients.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: February 14, 2023
    Inventors: Weidong Huang, Jodi Weidler, Jeff Sperinde, Mojgan Haddad, Michael Bates, John William Winslow, Xueguang Jin, Gerald J. Wallweber
  • Methods for determining the likelihood of survival and for predicting likelihood of metastasis in cancer patients
    Patent number: 11401344
    Abstract: The present invention relates generally to methods of accurately quantifying HER2 and/or p95 expression in subjects with a HER2 positive cancer and indicating the risk of brain relapse in such patients.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: August 2, 2022
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Weidong Huang, Jodi Weidler, Jeff Sperinde, Mojgan Haddad, Michael Bates, John William Winslow, Xueguang Jin, Gerald J. Wallweber, Jennifer W. Cook, Gundo Diedrich, Laurie Goodman, Ali Mukherjee, Gordon Parry, Stephen J. Williams
  • Methods for Determining the Likelihood of Survival and for Predicting Likelihood of Metastasis in Cancer Patients
    Publication number: 20190257836
    Abstract: The present invention relates generally to methods of accurately quantifying HER2 and/or p95 expression in subjects with a HER2 positive cancer and indicating the risk of brain relapse in such patients.
    Type: Application
    Filed: October 22, 2018
    Publication date: August 22, 2019
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Weidong Huang, Jodi Weidler, Jeff Sperinde, Mojgan Haddad, Michael Bates, John William Winslow, Xueguang Jin, Gerald J. Wallweber
  • Methods of producing antibodies specific for p95
    Patent number: 10273308
    Abstract: The disclosure provides methods of making antibodies specific for p95.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: April 30, 2019
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Jeff Sperinde, John William Winslow, Xueguang Jin, Gerald J. Wallweber
  • Methods for Determining the Likelihood of Survival and for Predicting Likelihood of Metastasis in Cancer Patients
    Publication number: 20190055319
    Abstract: The present invention relates generally to methods of accurately quantifying HER2 and/or p95 expression in subjects with a HER2 positive cancer and indicating the risk of brain relapse in such patients.
    Type: Application
    Filed: October 22, 2018
    Publication date: February 21, 2019
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Weidong Huang, Jodi Weidler, Jeff Sperinde, Mojgan Haddad, Michael Bates, John William Winslow, Xueguang Jin, Gerald J. Wallweber, Jennifer W. Cook, Gundo Diedrich, Laurie Goodman, Ali Mukherjee, Gordon Parry, Stephen J. Williams
  • Methods of Producing Antibodies Specific for p95
    Publication number: 20150376293
    Abstract: The invention provides methods of measuring and/or quantifying the presence and/or amount of p95 and/or p95 complex in a sample. The invention also provides antibodies specific for p95, and methods of making such antibodies.
    Type: Application
    Filed: June 12, 2015
    Publication date: December 31, 2015
    Inventors: Jeff Sperinde, John William Winslow, Xueguang Jin, Gerald J. Wallweber
  • Methods and assays for measuring p95 and/or p95 complexes in a sample and antibodies specific for p95
    Patent number: 9081019
    Abstract: The invention provides methods of measuring and/or quantifying the presence and/or amount of p95 and/or p95 complex in a sample. The invention also provides antibodies specific for p95.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: July 14, 2015
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Jeff Sperinde, John William Winslow, Xueguang Jin, Gerald J. Wallweber
  • Methods and Assays for Measuring p95 and/or p95 Complexes in a Sample and Antibodies Specific for p95
    Publication number: 20130316380
    Abstract: The invention provides methods of measuring and/or quantifying the presence and/or amount of p95 and/or p95 complex in a sample. The invention also provides antibodies specific for p95.
    Type: Application
    Filed: June 6, 2013
    Publication date: November 28, 2013
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Jeff Sperinde, John William Winslow, Xueguang Jin
  • Methods and assays for measuring p95 and/or p95 complexes in a sample and antibodies specific for p95
    Patent number: 8470542
    Abstract: The invention provides methods of measuring and/or quantifying the presence and/or amount of p95 and/or p95 complex in a sample. The invention also provides antibodies specific for p95.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: June 25, 2013
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Jeff Sperinde, John William Winslow, Xueguang Jin
  • Methods and Assays for Measuring p95 and/or p95 in a Sample and Antibodies Specific for p95
    Publication number: 20100143927
    Abstract: The invention provides methods of measuring and/or quantifying the presence and/or amount of p95 and/or p95 complex in a sample. The invention also provides antibodies specific for p95.
    Type: Application
    Filed: December 1, 2009
    Publication date: June 10, 2010
    Inventors: Jeff Sperinde, John Willam Winslow, Xueguang Jin
  • Intracellular complexes as biomarkers
    Publication number: 20040229299
    Abstract: The invention provides a method for determining a disease status of a patient by measuring expression levels of selected intracellular complexes. In one aspect of the invention, the activation status of apoptotic pathways in a patient sample is determined by measuring relative amounts of protein-protein complexes that are characteristic of the apoptotic pathways. In particular, the invention provides a method of determining the activation status of the mitochondrial apoptotic pathway by simultaneously measuring relative amounts of complexes between 14-3-3 proteins and BAD proteins on the one hand and complexes of Bcl-2 proteins and BAD proteins on the other hand. Preferably, methods of the invention are implemented by using sets of binding compounds having releasable molecular tags that are specific for multiple components of one or more complexes formed within apoptotic pathways. After binding, molecular tags are released and separated from the assay mixture for analysis.
    Type: Application
    Filed: March 30, 2004
    Publication date: November 18, 2004
    Inventors: M. Youssouf Badal, Xueguang Jin, Hossein Salimi-Moosavi, Singh Sharat