Patents by Inventor Xueheng Cheng

Xueheng Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of donepezil
    Patent number: 9249098
    Abstract: This invention relates to novel compounds and hydrochloric acid salts thereof. More specifically, this invention relates to novel compounds and hydrochloric acid salts thereof derived from donepezil. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering an acetylcholinesterase (AChE) inhibitor, such as donepezil.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: February 2, 2016
    Inventor: Xueheng Cheng
  • NOVEL DERIVATIVES OF DONEPEZIL
    Publication number: 20150225343
    Abstract: This invention relates to novel compounds and hydrochloric acid salts thereof. More specifically, this invention relates to novel compounds and hydrochloric acid salts thereof derived from donepezil. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering an acetylcholinesterase (AChE) inhibitor, such as donepezil.
    Type: Application
    Filed: July 10, 2012
    Publication date: August 13, 2015
    Inventor: Xueheng Cheng
  • Method for improving the properties of a drug lead compound
    Patent number: 8815781
    Abstract: The present patent application introduces methods for generating mixture compound libraries from a drug lead. The mixture compound libraries are then screened for the discovery of modified drug lead compounds which possess desired improved drug properties. The process utilizes a non-selective reaction to modify the drug lead compound structure. Compared to existing methods of modifying a drug lead compound, this new method can modify more structural positions of a drug lead compound. As a consequence, there will be greater probability of finding a product with improved drug properties.
    Type: Grant
    Filed: November 15, 2010
    Date of Patent: August 26, 2014
    Inventor: Xueheng Cheng
  • Derivatives of erlotinib
    Patent number: 8575339
    Abstract: This invention relates to novel compounds and hydrochloric acid salts thereof. More specifically, this invention relates to novel compounds and hydrochloric acid salts thereof derived from erlotinib. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering an epidermal growth factor receptor tyrosine kinase (EGFR) inhibitor, such as erlotinib.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: November 5, 2013
    Inventor: Xueheng Cheng
  • NOVEL DERIVATIVES OF ERLOTINIB
    Publication number: 20130012528
    Abstract: This invention relates to novel compounds and hydrochloric acid salts thereof. More specifically, this invention relates to novel compounds and hydrochloric acid salts thereof derived from erlotinib. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering an epidermal growth factor receptor tyrosine kinase (EGFR) inhibitor, such as erlotinib.
    Type: Application
    Filed: July 5, 2011
    Publication date: January 10, 2013
    Inventor: Xueheng Cheng
  • METHOD FOR IMPROVING THE PROPERTIES OF A DRUG LEAD COMPOUND
    Publication number: 20110118124
    Abstract: The present patent application introduces methods for generating mixture compound libraries from a drug lead. The mixture compound libraries are then screened for the discovery of modified drug lead compounds which possess desired improved drug properties. The process utilizes a non-selective reaction to modify the drug lead compound structure. Compared to existing methods of modifying a drug lead compound, this new method can modify more structural positions of a drug lead compound. As a consequence, there will be greater probability of finding a product with improved drug properties.
    Type: Application
    Filed: November 15, 2010
    Publication date: May 19, 2011
    Inventor: Xueheng Cheng