Abstract: The present invention discloses a highly effective flame-retardant lightweight and soft multi-fiber blended fabric and a preparation method thereof. The fabric comprises 82 to 87 wt % of base fabric, 5 to 8 wt % of flame retardant and 8 to 10 wt % of antistatic agent. The base fabric comprises 45 to 48 wt % of polyacrylonitrile fibers, 40 to 42 wt % of cellulose fibers, 6 to 9 wt % of polyacrylate fibers and 6 to 8 wt % of polyamide fibers in parts by mass. The material has the characteristics of highly effective flame retardance, lightweightness and softness, with the gram weight being 215 g/m. A test shows that the material can come up to the NFPA2112 standard, and the arc-proof ATPV is greater than 8 cal/cm2.