Abstract: Compositions and methods for inhibiting the corrosion of metals in contact with an aqueous system are provided. For example, the corrosion inhibitor composition of the present embodiments can include an oxyanion of an amphoteric material, a silicate, and an additional component. The corrosion inhibitor can be substantially phosphate free or free of phosphorus. The additional component can include, for example, a hydroxycarboxylic acid.

Abstract: Methods, systems, and apparatuses for multichannel, matrix-based testing of electrochemical materials are described herein. The system provides an electrochemical testing apparatus that consists of a bottom block having a first array of N×M receiving wells, and a top block with a second array of N×M chambers, with each of the N×M chambers having an electrical connector. The method involves inserting, into a number of the first array of N×M receiving wells, one or more electrochemical compositions to be tested. The method then involves closing the top block onto the bottom block. When the top and bottom blocks are closed, the N×M receiving wells and N×M chambers are aligned, thereby forming N×M testing cells. Finally, the method involves measuring one or more properties of the electrochemical composition inserted in the plurality of the N×M receiving wells.

Abstract: Disclosed is a grouting and water blocking method for a hard rock stratum. The grouting and water blocking method include the following steps. At first, hydrogeological information and coal seam information of a hard rock stratum is obtained. Then, a drilling trajectory of the hard rock stratum is determined based on the hydrogeological information and the coal seam information. Later, at least one drilling device is determined corresponding to the drilling trajectory based on types of multiple rock layers contained in the hard rock stratum. After that, the multiple rock layers contained in the hard rock stratum are drilled sequentially according to the drilling trajectory using the at least one drilling device. At last, in response to determining there is a water leakage area, the water leakage area is grouted.

Abstract: Provided are an anti-B7H3 antibody and the use thereof. A variable region of the antibody comprises amino acid sequences as shown in SEQ ID NOs: 25-39. The anti-B7H3 antibodies 26B6, 6F7, 2B8, and 23H1 have a significant binding capability to B7H3, can not only bind to purified or free B7H3 protein, but also can bind to B7H3 protein on a cell surface; and after humanized modification, the affinity between the antibody and B7H3 is further improved, and the antibody has important application prospects in clinical diagnosis and/or treatment of B7H3-positive tumors.

Abstract: A microdevice for monitoring a target analyte is provided. The microdevice can include a field effect transistor comprising a substrate, a gate electrode, and a microfluidic channel including graphene. The microfluidic channel can be formed between drain electrodes and source electrodes on the substrate. The microdevice can also include at least one aptamer functionalized on a surface of the graphene. The at least one aptamer can be adapted for binding to the target analyte. Binding of the target analyte to the at least one aptamer can alter the conductance of the graphene.

Abstract: A chimeric antigen receptor fusion protein co-expressing IL-7 and CCR2b, and application thereof are provided. The fusion protein includes a chimeric antigen receptor, a 2A peptide, IL-7, a 2A peptide and CCR2b which are sequentially linked in series.

Abstract: A method of analyzing a substrate contacting a fluid present in an industrial system is provided. The method comprises creating a series of digital images of the substrate while contacting the fluid present in the industrial system. A region of interest in the series of digital images of the substrate is defined. A corrosion feature in the region of interest in the series of digital images of the substrate is identified. The corrosion feature in the region of interest in the series of digital images of the substrate is analyzed to determine a corrosion trend of the industrial system. In certain embodiments of the method, the fluid is industrial water, and the industrial system is an industrial water system.

Abstract: An automated coin cell battery manufacturing system can include a holding arrangement, an electrolyte dispensing component, a case providing component, a pick and place component, and a crimping component. The holding arrangement can hold multiple partially assembled coin cells that can each include electrode(s) and a spacer within a coin cell cap. The electrolyte dispensing component can automatically dispense electrolyte material into the partially assembled coin cells, and the electrolyte material can be different for different coin cells. The case providing component can store multiple coin cell cases and automatically provide the stored coin cell cases. The pick and place component can automatically pick the coin cell cases from the case providing component and can automatically place the coin cell cases on the multiple partially assembled coin cells to form fully assembled coin cells within the holding arrangement. The crimping component can automatically crimp the fully assembled coin cells.

Abstract: Provided are an anti-B7H3 chimeric antigen receptor and an application thereof. The anti-B7H3 chimeric antigen receptor comprises an antigen binding domain, a hinge region, a transmembrane domain and a signaling transfer structural domain. The antigen binding domain is an anti-human B7H3 antibody. The anti-B7H3 chimeric antigen receptor has a specific targeting effect on B7H3-positive tumor cells, T cells that express the anti-B7H3 chimeric antigen receptor have significant killing effects in vitro and in vivo, can effectively remove the B7H3-positive tumor cells, and having important significance in the field of tumor therapy.

Abstract: Provided are an anti-Claudin 18.2 antigen-binding fragment or antibody, and the use thereof. CDR3 of a heavy chain variable region of the antigen-binding fragment comprises an amino acid sequence shown in SEQ ID NO. 3. CDR3 of a light chain variable region of the antigen-binding fragment comprises an amino acid sequence shown in SEQ ID NO. 6. The provided antigen-binding fragment and anti-Claudin 18.2 antibody can specifically bind to a variety of sources of Claudin 18.2 proteins, have no binding effect on other proteins, and have a high specificity. In addition, a chimeric antigen receptor and a CAR-T cell prepared by means of the antibody have obvious cytotoxicity on cells stably expressing the Claudin 18.2 protein.

Abstract: The present application is related to a detection device and method for coronavirus and influenza virus. The device comprises a detection module (20), a signal processing circuit (30), a controller (40), a displayer (50), a digital-to-analog conversion circuit (60), and a clock (70). Noticeably, the detection module (20) comprises a sample cell, and a transistor sensor combination integrated in the sample cell and used for measuring different targets. The detection module (20) may comprise a sample cell array to realize simultaneous detection of a plurality of samples to be detected. The detection method comprises the following steps: adding a sample to be detected into a sample cell, reading an electrical signal response of each transistor sensor in the sample cell to judge whether the sample to be detected contains a virus to be detected or not. The present application belongs to the technical field of biological detection.

Abstract: Described herein are systems and methods for object detection to achieve hard real-time performance with low latency. Real-time object detection frameworks are disclosed. In one or more embodiments, a framework comprises a first CPU core, a second CPU core, and a plurality of shaves. In one or more embodiments, the first CPU core handles general CPU tasks, while the second CPU core handles the image frames from a camera sensor and computation task scheduling. In one or more embodiments, the scheduled computation tasks are implemented by the plurality of shaves using at least one object-detection model to detect an object in an image frame. In one or more embodiments, computation results from the object-detection model with a higher detection probability is used to form an output for object detection. In one or more embodiments, the object-detection models share some parameters for smaller size and higher implementing speed.

Abstract: The present application is related to a detection device and method for coronavirus and influenza virus. The device comprises a detection module (20), a signal processing circuit (30), a controller (40), a displayer (50), a digital-to-analog conversion circuit (60), and a clock (70). Noticeably, the detection module (20) comprises a sample cell, and a transistor sensor combination integrated in the sample cell and used for measuring different targets. The detection module (20) may comprise a sample cell array to realize simultaneous detection of a plurality of samples to be detected. The detection method comprises the following steps: adding a sample to be detected into a sample cell, reading an electrical signal response of each transistor sensor in the sample cell to judge whether the sample to be detected contains a virus to be detected or not. The present application belongs to the technical field of biological detection.

Abstract: The disclosed systems and method utilize the autofluorescence, optic imaging, and heat transfer resistance technologies to monitor the same simulated surface area for deposits. The systems and methods may provide continuous monitoring, detection, characterization and quantification of deposits. Utilizing this information, an associated control system may initiate alarms, initiate a chemical treatment operation, and adjust corresponding chemical treatment and preventive protocols to minimize and/or eradicate the issue.

Abstract: A method of analyzing a substrate contacting a fluid present in an industrial system is provided. The method comprises creating a series of digital images of the substrate while contacting the fluid present in the industrial system. A region of interest in the series of digital images of the substrate is defined. A corrosion feature in the region of interest in the series of digital images of the substrate is identified. The corrosion feature in the region of interest in the series of digital images of the substrate is analyzed to determine a corrosion trend of the industrial system. In certain embodiments of the method, the fluid is industrial water, and the industrial system is an industrial water system.

Abstract: Provided is an anti-CLL1 antibody and an application thereof. The variable region of the anti-CLL1 antibody includes the CDRs of SEQ ID NO: 1 to 6, SEQ ID NO: 5, and SEQ ID NO: 7 to 11 or SEQ ID NO: 12 to 17. The anti-CLL1 antibody of the present application has significant binding ability to both free and cell surface CLL1. After humanization, the affinity of the antibody to CLL1 is further improved, and it has important application prospect in the clinical diagnosis and/or treatment of tumors.

Abstract: Disclosed are systems and methods for generating candidate recipes for batch testing battery recipes in robotics laboratory equipment. In one embodiment, the candidate recipes in a batch, share the maximum number of chemicals in common, while as a batch, they utilize a minimum number of chemicals. The candidate recipes are identified by constructing a graph where an initial selection of recipes are placed at each node. The graph yields the candidate recipes in the batch.

Abstract: A method of analyzing a substrate contacting a fluid present in an industrial system is provided. The method comprises creating a series of digital images of the substrate while contacting the fluid present in the industrial system. A region of interest in the series of digital images of the substrate is defined. A corrosion feature in the region of interest in the series of digital images of the substrate is identified. The corrosion feature in the region of interest in the series of digital images of the substrate is analyzed to determine a corrosion trend of the industrial system. In certain embodiments of the method, the fluid is industrial water, and the industrial system is an industrial water system.

Abstract: The invention provides a product for inhibiting corrosion in a closed loop industrial water system containing a corrosion sensitive metal, the product comprising: a carboxylic acid-based corrosion inhibitor, an azole-based corrosion inhibitor, a nitrate-based corrosion inhibitor, and water. The invention also provides a method of inhibiting corrosion of a corrosion sensitive metal in a closed loop industrial water system, the method comprising treating water in the system with product of the invention, to provide treated water.

Abstract: Methods, systems, and apparatuses for multichannel, matrix-based testing of electrochemical materials are described herein. The system provides an electrochemical testing apparatus that consists of a bottom block having a first array of N×M receiving wells, and a top block with a second array of N×M chambers, with each of the N×M chambers having an electrical connector. The method involves inserting, into a number of the first array of N×M receiving wells, one or more electrochemical compositions to be tested. The method then involves closing the top block onto the bottom block. When the top and bottom blocks are closed, the N×M receiving wells and N×M chambers are aligned, thereby forming N×M testing cells. Finally, the method involves measuring one or more properties of the electrochemical composition inserted in the plurality of the N×M receiving wells.