Patents by Inventor Xuejun Wu

Xuejun Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10428013
    Abstract: Disclosed are amide compounds, preparation method and uses thereof, specifically, the compounds represented by formula I or pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, Q, X and n are defined as in the description. Also disclosed are a method for preparing the compounds of formula I, a composition containing the compounds, and the uses of the same in the preparation of medicaments for regulating blood lipid and/or preventing gallstone. The compounds of formula I disclosed in the present invention have stability in vitro, good solubility in the pharmaceutical organic solvents and favorable bioavailability in animals.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: October 1, 2019
    Assignees: Shanghai Institute of Phamaceutical Industry, China State Institute of Pharmaceutical Industry
    Inventors: Zhenpeng Yu, Gouping Wang, Zhen Zhang, Minyu Liu, Xiaoling Huang, Ying Liu, Lin Xiao, Li Cai, Xuejun Wu, Yifang Deng, Mianli Pan, Renhai Chen, Shenrong Tang, Quanhai Liu
  • Publication number: 20190167721
    Abstract: The present invention provides a glycosylated CEA-specific single-chain antibody, and a chimeric antigen receptor (CAR) targeting a glycosylated CEA, which can be used in manufacture of an agent or a medicament for diagnosis or treatment of a tumor overexpressing glycosylated CEA.
    Type: Application
    Filed: July 27, 2017
    Publication date: June 6, 2019
    Inventors: Daiming FAN, Yongzhan NIE, Kaichun WU, Yueqiong CAO, Jijun YUAN, Xuejun YU
  • Patent number: 9712374
    Abstract: In general, the invention is directed to techniques for scheduling resource access within an intermediate network device. For example, as described herein, a device receives packets for a plurality of sessions that include application-layer data for the sessions. The device determines a weight for each of the plurality of sessions and, during periods of resource congestion, selects one or more sessions for additional resource allocation based on the respective weights of the sessions. The device allocates additional memory resources to selected sessions to enable further buffering of application-layer data such that the device may apply the service to multiple sessions concurrently despite the resource congestion.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: July 18, 2017
    Assignee: Juniper Networks, Inc.
    Inventors: Wei Cao, Xia Zhu, Xuejun Wu
  • Patent number: 8962880
    Abstract: An amorphous asiatic tromethamine salt and the preparation method thereof. The method includes the steps of: (1) dissolving asiatic acid in an organic solvent; step (2) mixing with tromethamine; step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: February 24, 2015
    Assignee: Shanghai Institute of Pharmaceutical Industry
    Inventors: Guobin Ren, Ying Liu, Jinyao Chen, Xiaoling Huang, Lin Xiao, Li Cai, Zhen Zhang, Xuejun Wu, Haiyan Sun, Quanhai Liu, Liling Jin, Minyu Liu, Yifang Deng, Zhiru Xu, Renhai Chen, Chungang Li, Xiangduan Tan, Yan Qin
  • Publication number: 20140243553
    Abstract: An amorphous asiatic tromethamine salt and the preparation method thereof. The method includes the steps of: (1) dissolving asiatic acid in an organic solvent; step (2) mixing with tromethamine; step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
    Type: Application
    Filed: March 21, 2012
    Publication date: August 28, 2014
    Applicant: SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
    Inventors: Guobin Ren, Ying Liu, Jinyao Chen, Xiaoling Huang, Lin Xiao, Li Cai, Zhen Zhang, Xuejun Wu, Haiyan Sun, Quanhai Liu, Liling Jin, Minyu Liu, Yifang Deng, Zhiru Xu, Renhai Chen, Chungang Li, Xiangduan Tan, Yan Qin
  • Publication number: 20140128463
    Abstract: Disclosed are amide compounds, preparation method and uses thereof, specifically, the compounds represented by formula I or pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, Q, X and n are defined as in the description. Also disclosed are a method for preparing the compounds of formula I, a composition containing the compounds, and the uses of the same in the preparation of medicaments for regulating blood lipid and/or preventing gallstone. The compounds of formula I disclosed in the present invention have stability in vitro, good solubility in the pharmaceutical organic solvents and favorable bioavailability in animals.
    Type: Application
    Filed: June 25, 2012
    Publication date: May 8, 2014
    Applicants: China State Institute of Pharmaceutic Industry, Shanghai Institute of Pharmaceutical Industry
    Inventors: Zhenpeng Yu, Gouping Wang, Zhen Zhang, Minyu Liu, Xiaoling Huang, Ying Liu, Lin Xiao, Li Cai, Xuejun Wu, Yifang Deng, Mianli Pan, Renhai Chen, Shenrong Tang, Quanhai Liu
  • Patent number: 8258176
    Abstract: The invention discloses a dithiolopyrrolone compound represented by formula I or its pharmaceutically acceptable salts, wherein X1, R1, R2, R3, R4 are defined as in the description. The invention also discloses the preparation of such compounds, and the use of such compounds in preparation of medicaments for increasing peripheral white blood cells and in preparation of ancillary medicaments for inhibiting the decrease of peripheral white blood cells in radiotherapy or chemotherapy.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: September 4, 2012
    Assignees: Shanghai Institute of Pharmaceutical Industry, Shanghai Modern Pharmaceutical Co., Ltd.
    Inventors: Guoping Wang, Quanhai Liu, Haiyan Sun, Wei Wu, Jian Hou, Lin Yao, Chungang Li, Minyu Liu, Fei Li, Xuejun Wu, Shuai Zhao
  • Patent number: 8261352
    Abstract: A method includes receiving a data unit, determining whether a current state, associated with a deterministic finite automata (DFA) that includes a portion of states in a bitmap and a remaining portion of states in a DFA table, is a bitmap state or not, and determining whether a value corresponding to the data unit is greater than a threshold value, when it is determined that the current state is not a bitmap state. The method further includes determining whether the current state is insensitive, when it is determined that the value corresponding to the data unit is greater than the threshold value, where insensitive means that each next state is a same state for the current state, and selecting a default state, as a next state for the current, when it is determined that the current state is insensitive.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: September 4, 2012
    Assignee: Juniper Networks Inc.
    Inventors: Qingming Ma, Bryan Burns, Sheng Li, Na Liu, Xuejun Wu, Shan Yu, Li Zheng
  • Publication number: 20100229238
    Abstract: A method includes receiving a data unit, determining whether a current state, associated with a deterministic finite automata (DFA) that includes a portion of states in a bitmap and a remaining portion of states in a DFA table, is a bitmap state or not, and determining whether a value corresponding to the data unit is greater than a threshold value, when it is determined that the current state is not a bitmap state. The method further includes determining whether the current state is insensitive, when it is determined that the value corresponding to the data unit is greater than the threshold value, where insensitive means that each next state is a same state for the current state, and selecting a default state, as a next state for the current, when it is determined that the current state is insensitive.
    Type: Application
    Filed: May 19, 2009
    Publication date: September 9, 2010
    Applicant: Juniper Networks Inc.
    Inventors: Qingming Ma, Bryan Burns, Sheng Li, Na Liu, Xuejun Wu, Shan Yu, Li Zheng
  • Publication number: 20100210856
    Abstract: The invention discloses a dithiolopyrrolone compound represented by formula I or its pharmaceutically acceptable salts, wherein X1, R1, R2, R3, R4 are defined as in the description. The invention also discloses the preparation of such compounds, and the use of such compounds in preparation of medicaments for increasing peripheral white blood cells and in preparation of ancillary medicaments for inhibiting the decrease of peripheral white blood cells in radiotherapy or chemotherapy.
    Type: Application
    Filed: August 29, 2008
    Publication date: August 19, 2010
    Applicants: SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY, SHANGHAI MODERN PHARMACEUTICAL CO., LTD
    Inventors: Guoping Wang, Quanhai Liu, Haiyan Sun, Wei Wu, Jian Hou, Lin Yao, Chungang Li, Minyu Liu, Fei Li, Xuejun Wu, Shuai Zhao
  • Patent number: 6867194
    Abstract: Sugar-modified SIN-1 compositions are provided. The compositions are useful for generating NO in response to hydrolytic activity of a glycosidase specific for the O-glycosidic bond between the sugar and SIN-1 moieties. Pharmaceutical compositions containing the sugar-modified SIN-1 compositions and methods of using the compositions are also provided.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: March 15, 2005
    Assignee: Wayne State University
    Inventors: Peng George Wang, Xuejun Wu, Xiaoping Tang
  • Publication number: 20030050256
    Abstract: Sugar-modified SIN-1 compositions are provided. The compositions are useful for generating NO in response to hydrolytic activity of a glycosidase specific for the O-glycosidic bond between the sugar and SIN-1 moieties. Pharmaceutical compositions containing the sugar-modified SIN-1 compositions and methods of using the compositions are also provided.
    Type: Application
    Filed: August 9, 2001
    Publication date: March 13, 2003
    Inventors: Peng George Wang, Xuejun Wu, Xiaoping Tang