Abstract: The present invention relates to a tricyclic compound used as a GPR84 antagonist, and in particular relates to a tricyclic compound having a structure shown in formula I, and tautomers, stereoisomers, hydrates, solvates, pharmaceutically acceptable salts or prodrugs thereof; the definitions of the ring Cy, L1, R1 are as described in the present invention; the tricyclic compound has significant GPR84 antagonism, good pharmaceutical developability and high safety.

Abstract: An optical waveguide includes a cladding layer, a Si layer, a REO layer, and a cap layer. The REO layer is made of a single-crystal rare earth oxide, and is formed on the Si layer. The cap layer is formed on the REO layer. The cap layer may be made of a material transparent to light to be guided. The cap layer has a stripe shape extending in a direction in which light is guided.

Abstract: An optical waveguide includes a cladding layer, a Si layer, a REO layer, and a cap layer. The REO layer is made of a single-crystal rare earth oxide, and is formed on the Si layer. The cap layer is formed on the REO layer. The cap layer may be made of a material transparent to light to be guided. The cap layer has a stripe shape extending in a direction in which light is guided.

Abstract: A mobile device communicates wirelessly with an annotation device and a to-be-annotated electronic device. The mobile device includes a processor, a memory, a UWB tag, a direction sensor, and a computer program stored in the memory, and when the computer program executed by the processor, the mobile device is enabled to perform: receiving a first input after the mobile device moves to a location of the electronic device; recording a location of the mobile device in response to the first input, where the location of the mobile device is the location of the electronic device; and popping up a first control window for the electronic device after the mobile device moves to another location and points to the electronic device. According to this application, the mobile device can control, by using the annotation device, an electronic device on which no UWB chip is installed.

Abstract: The disclosure provides a naphthylurea compound having a formula I. In the formula, m and n represent a number of CH2, and are an integer from 1 to 10; k and z represent a number of CH2, and are an integer from 0 to 6; and p represents a number of CH2, and is 1, 2 or 3; and X is O or S.

Abstract: A licensing system and related methods are described utilizing aspects of distributed ledger technologies to facilitate trusted and verifiable licensing transactions for creative works. A client device can include an asset editing tool for incorporating an asset selected from a plurality of licensable assets into a new creative work. The selected asset can be downloaded for incorporation into the new creative work. The new creative work incorporating the selected asset can be analyzed to determine an amount that the selected asset contributed to the new creative work, or an amount that the new creative work is attributable to the selected asset.

Abstract: The disclosure provides a naphthylurea compound having a formula I. R represents H, a C1-C5 straight-chain alkyl, a C1-C5 straight-chain alkyl with a halogen-substituted end or a 5-8-membered cycloalkyl; R1, R2, R3, R4, R5, R6, R7, R8, R9 at each occurrence represent H, F, Cl, Br, —CN, —CH3, —CF3, —OCH3, or —OCF3; R5 optionally represents phenyl, and M is H or —CH3; m represents a number of CH2, and is 0 or 1; n represents a number of CH2, and is 1, 2, 3, or 4; and p represents a number of CH2, and is 2; and X is O or S.

Abstract: Embodiments provide traceability of edits to a document, i.e., a verifiable and immutable provenance chain for the document. Systems and methods enable traceability of edits, by encoding, for states of the document, a fingerprint (e.g., a cryptographic hash of the document's contents) and an edit history within a block written to a distributed ledger (e.g., a blockchain). The ledger is maintained via a self-organizing peer-to-peer distributed ledger network. Once added to the ledger, the contents of a block (e.g., the document's fingerprint and edit history) are immutable and the integrity of the edit history encoded in the ledger is secure. The algorithm that generates the fingerprint is sensitive to edits of the document. The non-corruptible fingerprint encoded in the ledger is employable to detect any edits that are not included in the encoded edit history and/or inconsistent with a currently available version of the document.

Abstract: The present disclosure provides synthetic collagen and methods of making and using synthetic collagen that include a synthetic collagen that facilitates wound closure comprising an isolated and purified triple helical backbone protein that facilitates wound closure comprising one or more alteration in a triple helical backbone protein sequence, that stabilize the isolated and purified triple helical backbone protein and does not disrupt an additional collagen ligand interaction; and one or more integrin binding motifs, wherein the isolated and purified triple helical backbone protein facilitates wound closure.

Abstract: Embodiments relate to a smart contract platform that facilitates creation, execution and verification of customized smart contracts. The smart contract platform enables design of customized smart contracts for execution and verification on a distributed ledger network, including smart contracts with logic for querying and fetching sensitive transactional data from participant nodes. A distributed ledger can store tokens indicating successful completion of one or more transaction elements without making some or all the associated transactional data visible. A smart contract form viewer can be used to view and interact with a smart contract form linked to the smart contract. The smart contract form can present contractual provisions in natural language, present transactional data to an authorized user, and accept entry or validation of designated transaction data.

Abstract: Embodiments of the present invention provide systems, methods, and computer storage media directed to a proof and attestation service that can confirm the veracity of a claim or a statement of truth based on data dynamically-retrieved from various data repositories. A server device receives, from a client device, a request to determine the veracity of a claim or a statement of truth. The server device is generally a trusted computing device, having privileged-access to a variety of data repositories that the client device may or may not access. The server device can select one or more data repositories based on the claim, obtain results data from the selected one or more data repositories, and evaluate each result to determine whether it corresponds to or contradicts the claim. A veracity score can be calculated for the claim or for a result that corresponds to or contradicts the claim.

Abstract: In view of the lack of anti-cancer targeted drugs in the prior art, the invention provides a naphthylamine compound and a biologically acceptable salt thereof, a preparation method thereof, and an application thereof. The naphthylamine compound and the biologically acceptable salt thereof provided by the invention can bind to protein sites related to tumor diseases in organisms through functional groups in the structure, and have hydrogen bonds and hydrophobic interactions with receptors, so as to achieve the purpose of inhibiting tumor cell proliferation.

Abstract: A licensing system and related methods are described utilizing aspects of distributed ledger technologies to facilitate trusted and verifiable licensing transactions for creative works. A client device can include an asset editing tool for incorporating an asset selected from a plurality of licensable assets into a new creative work. The selected asset can be downloaded for incorporation into the new creative work. The new creative work incorporating the selected asset can be analyzed to determine an amount that the selected asset contributed to the new creative work, or an amount that the new creative work is attributable to the selected asset.

Abstract: A licensing system and related methods are described utilizing aspects of distributed ledger technologies to facilitate trusted and verifiable licensing transactions for creative works. A client device can include an asset editing tool for incorporating an asset selected from a plurality of licensable assets into a new creative work. The selected asset can be downloaded for incorporation into the new creative work. The new creative work incorporating the selected asset can be analyzed to determine an amount that the selected asset contributed to the new creative work, or an amount that the new creative work is attributable to the selected asset.

Abstract: Embodiments provide traceability of edits to a document, i.e., a verifiable and immutable provenance chain for the document. Systems and methods enable traceability of edits, by encoding, for states of the document, a fingerprint (e.g., a cryptographic hash of the document's contents) and an edit history within a block written to a distributed ledger (e.g., a blockchain). The ledger is maintained via a self-organizing peer-to-peer distributed ledger network. Once added to the ledger, the contents of a block (e.g., the document's fingerprint and edit history) are immutable and the integrity of the edit history encoded in the ledger is secure. The algorithm that generates the fingerprint is sensitive to edits of the document. The non-corruptible fingerprint encoded in the ledger is employable to detect any edits that are not included in the encoded edit history and/or inconsistent with a currently available version of the document.

Abstract: Embodiments relate to a smart contract platform that facilitates creation, execution and verification of customized smart contracts. The smart contract platform enables design of customized smart contracts for execution and verification on a distributed ledger network, including smart contracts with logic for querying and fetching sensitive transactional data from participant nodes. A distributed ledger can store tokens indicating successful completion of one or more transaction elements without making some or all the associated transactional data visible. A smart contract form viewer can be used to view and interact with a smart contract form linked to the smart contract. The smart contract form can present contractual provisions in natural language, present transactional data to an authorized user, and accept entry or validation of designated transaction data.

Abstract: Embodiments of the present invention provide systems, methods, and computer storage media directed to a proof and attestation service that can confirm the veracity of a claim or a statement of truth based on data dynamically-retrieved from various data repositories. A server device receives, from a client device, a request to determine the veracity of a claim or a statement of truth. The server device is generally a trusted computing device, having privileged-access to a variety of data repositories that the client device may or may not access. The server device can select one or more data repositories based on the claim, obtain results data from the selected one or more data repositories, and evaluate each result to determine whether it corresponds to or contradicts the claim. A veracity score can be calculated for the claim or for a result that corresponds to or contradicts the claim.

Abstract: Embodiments of the present invention provide systems, methods, and computer storage media directed to a proof and attestation service that can confirm the veracity of a claim or a statement of truth based on data dynamically-retrieved from various data repositories. A server device receives, from a client device, a request to determine the veracity of a claim or a statement of truth. The server device is generally a trusted computing device, having privileged-access to a variety of data repositories that the client device may or may not access. The server device can select one or more data repositories based on the claim, obtain results data from the selected one or more data repositories, and evaluate each result to determine whether it corresponds to or contradicts the claim. A veracity score can be calculated for the claim or for a result that corresponds to or contradicts the claim.

Abstract: One embodiment of the present invention provides a system that facilitates the transfer of a software license from a first client to a second client. The system operates by receiving a request at the first client to deactivate the software license for an associated application installed on the first client. The system then receives a deactivation request that includes an identifier for the license at a license activation server from the first client. Next, the system validates the identifier on the license activation server to determine if the identifier is a valid identifier. If so, the system sends a deactivation message to the first client, receives a deactivation response from the first client, and increments a count of license instances available for the identifier on the license activation server.

Abstract: Embodiments relate to a smart contract platform that facilitates creation, execution and verification of customized smart contracts. The smart contract platform enables design of customized smart contracts for execution and verification on a distributed ledger network, including smart contracts with logic for querying and fetching sensitive transactional data from participant nodes. A distributed ledger can store tokens indicating successful completion of one or more transaction elements without making some or all the associated transactional data visible. A smart contract form viewer can be used to view and interact with a smart contract form linked to the smart contract. The smart contract form can present contractual provisions in natural language, present transactional data to an authorized user, and accept entry or validation of designated transaction data.