Abstract: The disclosure provides a naphthylurea compound having a formula I. R represents H, a C1-C5 straight-chain alkyl, a C1-C5 straight-chain alkyl with a halogen-substituted end or a 5-8-membered cycloalkyl; R1, R2, R3, R4, R5, R6, R7, R8, R9 at each occurrence represent H, F, Cl, Br, —CN, —CH3, —CF3, —OCH3, or —OCF3; R5 optionally represents phenyl, and M is H or —CH3; m represents a number of CH2, and is 0 or 1; n represents a number of CH2, and is 1, 2, 3, or 4; and p represents a number of CH2, and is 2; and X is O or S.

Abstract: A method of processing an image includes: acquiring a first image for a target object by using a first imaging method (S110); acquiring a second image for the target object by using a second imaging method (S120); constructing a first sub-image and a second sub-image based on the first image (S130); constructing a third sub-image and a fourth sub-image based on the second image (S140); and determining a pixel value distribution information of a fused image based on a pixel value distribution information of each of the first sub-image, the second sub-image, the third sub-image, and the fourth sub-image, so as to obtain the fused image (S150). An apparatus of processing an image, a computing device, and a computer-readable storage medium are further provided.

Abstract: Embodiments provide traceability of edits to a document, i.e., a verifiable and immutable provenance chain for the document. Systems and methods enable traceability of edits, by encoding, for states of the document, a fingerprint (e.g., a cryptographic hash of the document's contents) and an edit history within a block written to a distributed ledger (e.g., a blockchain). The ledger is maintained via a self-organizing peer-to-peer distributed ledger network. Once added to the ledger, the contents of a block (e.g., the document's fingerprint and edit history) are immutable and the integrity of the edit history encoded in the ledger is secure. The algorithm that generates the fingerprint is sensitive to edits of the document. The non-corruptible fingerprint encoded in the ledger is employable to detect any edits that are not included in the encoded edit history and/or inconsistent with a currently available version of the document.

Abstract: The present disclosure provides synthetic collagen and methods of making and using synthetic collagen that include a synthetic collagen that facilitates wound closure comprising an isolated and purified triple helical backbone protein that facilitates wound closure comprising one or more alteration in a triple helical backbone protein sequence, that stabilize the isolated and purified triple helical backbone protein and does not disrupt an additional collagen ligand interaction; and one or more integrin binding motifs, wherein the isolated and purified triple helical backbone protein facilitates wound closure.

Abstract: Embodiments relate to a smart contract platform that facilitates creation, execution and verification of customized smart contracts. The smart contract platform enables design of customized smart contracts for execution and verification on a distributed ledger network, including smart contracts with logic for querying and fetching sensitive transactional data from participant nodes. A distributed ledger can store tokens indicating successful completion of one or more transaction elements without making some or all the associated transactional data visible. A smart contract form viewer can be used to view and interact with a smart contract form linked to the smart contract. The smart contract form can present contractual provisions in natural language, present transactional data to an authorized user, and accept entry or validation of designated transaction data.

Abstract: Embodiments of the present invention provide systems, methods, and computer storage media directed to a proof and attestation service that can confirm the veracity of a claim or a statement of truth based on data dynamically-retrieved from various data repositories. A server device receives, from a client device, a request to determine the veracity of a claim or a statement of truth. The server device is generally a trusted computing device, having privileged-access to a variety of data repositories that the client device may or may not access. The server device can select one or more data repositories based on the claim, obtain results data from the selected one or more data repositories, and evaluate each result to determine whether it corresponds to or contradicts the claim. A veracity score can be calculated for the claim or for a result that corresponds to or contradicts the claim.

Abstract: In view of the lack of anti-cancer targeted drugs in the prior art, the invention provides a naphthylamine compound and a biologically acceptable salt thereof, a preparation method thereof, and an application thereof. The naphthylamine compound and the biologically acceptable salt thereof provided by the invention can bind to protein sites related to tumor diseases in organisms through functional groups in the structure, and have hydrogen bonds and hydrophobic interactions with receptors, so as to achieve the purpose of inhibiting tumor cell proliferation.

Abstract: A licensing system and related methods are described utilizing aspects of distributed ledger technologies to facilitate trusted and verifiable licensing transactions for creative works. A client device can include an asset editing tool for incorporating an asset selected from a plurality of licensable assets into a new creative work. The selected asset can be downloaded for incorporation into the new creative work. The new creative work incorporating the selected asset can be analyzed to determine an amount that the selected asset contributed to the new creative work, or an amount that the new creative work is attributable to the selected asset.

Abstract: A licensing system and related methods are described utilizing aspects of distributed ledger technologies to facilitate trusted and verifiable licensing transactions for creative works. A client device can include an asset editing tool for incorporating an asset selected from a plurality of licensable assets into a new creative work. The selected asset can be downloaded for incorporation into the new creative work. The new creative work incorporating the selected asset can be analyzed to determine an amount that the selected asset contributed to the new creative work, or an amount that the new creative work is attributable to the selected asset.

Abstract: Embodiments provide traceability of edits to a document, i.e., a verifiable and immutable provenance chain for the document. Systems and methods enable traceability of edits, by encoding, for states of the document, a fingerprint (e.g., a cryptographic hash of the document's contents) and an edit history within a block written to a distributed ledger (e.g., a blockchain). The ledger is maintained via a self-organizing peer-to-peer distributed ledger network. Once added to the ledger, the contents of a block (e.g., the document's fingerprint and edit history) are immutable and the integrity of the edit history encoded in the ledger is secure. The algorithm that generates the fingerprint is sensitive to edits of the document. The non-corruptible fingerprint encoded in the ledger is employable to detect any edits that are not included in the encoded edit history and/or inconsistent with a currently available version of the document.

Abstract: Embodiments relate to a smart contract platform that facilitates creation, execution and verification of customized smart contracts. The smart contract platform enables design of customized smart contracts for execution and verification on a distributed ledger network, including smart contracts with logic for querying and fetching sensitive transactional data from participant nodes. A distributed ledger can store tokens indicating successful completion of one or more transaction elements without making some or all the associated transactional data visible. A smart contract form viewer can be used to view and interact with a smart contract form linked to the smart contract. The smart contract form can present contractual provisions in natural language, present transactional data to an authorized user, and accept entry or validation of designated transaction data.

Abstract: Embodiments of the present invention provide systems, methods, and computer storage media directed to a proof and attestation service that can confirm the veracity of a claim or a statement of truth based on data dynamically-retrieved from various data repositories. A server device receives, from a client device, a request to determine the veracity of a claim or a statement of truth. The server device is generally a trusted computing device, having privileged-access to a variety of data repositories that the client device may or may not access. The server device can select one or more data repositories based on the claim, obtain results data from the selected one or more data repositories, and evaluate each result to determine whether it corresponds to or contradicts the claim. A veracity score can be calculated for the claim or for a result that corresponds to or contradicts the claim.

Abstract: Embodiments of the present invention provide systems, methods, and computer storage media directed to a proof and attestation service that can confirm the veracity of a claim or a statement of truth based on data dynamically-retrieved from various data repositories. A server device receives, from a client device, a request to determine the veracity of a claim or a statement of truth. The server device is generally a trusted computing device, having privileged-access to a variety of data repositories that the client device may or may not access. The server device can select one or more data repositories based on the claim, obtain results data from the selected one or more data repositories, and evaluate each result to determine whether it corresponds to or contradicts the claim. A veracity score can be calculated for the claim or for a result that corresponds to or contradicts the claim.

Abstract: One embodiment of the present invention provides a system that facilitates the transfer of a software license from a first client to a second client. The system operates by receiving a request at the first client to deactivate the software license for an associated application installed on the first client. The system then receives a deactivation request that includes an identifier for the license at a license activation server from the first client. Next, the system validates the identifier on the license activation server to determine if the identifier is a valid identifier. If so, the system sends a deactivation message to the first client, receives a deactivation response from the first client, and increments a count of license instances available for the identifier on the license activation server.

Abstract: Embodiments relate to a smart contract platform that facilitates creation, execution and verification of customized smart contracts. The smart contract platform enables design of customized smart contracts for execution and verification on a distributed ledger network, including smart contracts with logic for querying and fetching sensitive transactional data from participant nodes. A distributed ledger can store tokens indicating successful completion of one or more transaction elements without making some or all the associated transactional data visible. A smart contract form viewer can be used to view and interact with a smart contract form linked to the smart contract. The smart contract form can present contractual provisions in natural language, present transactional data to an authorized user, and accept entry or validation of designated transaction data.

Abstract: Embodiments provide traceability of edits to a document, i.e., a verifiable and immutable provenance chain for the document. In particular, embodiments facilitate providing analytics services for a distributed ledger. In implementation, a unique identifier associated with a digital document can be received from a remote computing device. Based on the received unique identifier, it is determined that the distributed ledger includes a first transaction corresponding to a first transitioned state of the digital document and a second transaction corresponding to a second transitioned state of the digital document. Each transaction includes the unique identifier, a first fingerprint of the digital document generated at a first time of a transitioned state, and a second fingerprint of the digital document generated at a second time of a previously transitioned state.

Abstract: Embodiments provide traceability of edits to a document, i.e., a verifiable and immutable provenance chain for the document. Systems and methods enable traceability of edits, by encoding, for states of the document, a fingerprint (e.g., a cryptographic hash of the document's contents) and an edit history within a block written to a distributed ledger (e.g., a blockchain). The ledger is maintained via a self-organizing peer-to-peer distributed ledger network. Once added to the ledger, the contents of a block (e.g., the document's fingerprint and edit history) are immutable and the integrity of the edit history encoded in the ledger is secure. The algorithm that generates the fingerprint is sensitive to edits of the document. The non-corruptible fingerprint encoded in the ledger is employable to detect any edits that are not included in the encoded edit history and/or inconsistent with a currently available version of the document.

Abstract: A licensing system and related methods are described utilizing aspects of distributed ledger technologies to facilitate trusted and verifiable licensing transactions for creative works. A client device can include an asset editing tool for incorporating an asset selected from a plurality of licensable assets into a new creative work. The selected asset can be downloaded for incorporation into the new creative work. The new creative work incorporating the selected asset can be analyzed to determine an amount that the selected asset contributed to the new creative work, or an amount that the new creative work is attributable to the selected asset.

Abstract: Embodiments of the present invention provide systems, methods, and computer storage media directed to a proof and attestation service that can confirm the veracity of a claim or a statement of truth based on data dynamically-retrieved from various data repositories. A server device receives, from a client device, a request to determine the veracity of a claim or a statement of truth. The server device is generally a trusted computing device, having privileged-access to a variety of data repositories that the client device may or may not access. The server device can select one or more data repositories based on the claim, obtain results data from the selected one or more data repositories, and evaluate each result to determine whether it corresponds to or contradicts the claim. A veracity score can be calculated for the claim or for a result that corresponds to or contradicts the claim.

Abstract: Embodiments relate to a smart contract platform that facilitates creation, execution and verification of customized smart contracts. The smart contract platform enables design of customized smart contracts for execution and verification on a distributed ledger network, including smart contracts with logic for querying and fetching sensitive transactional data from participant nodes. A distributed ledger can store tokens indicating successful completion of one or more transaction elements without making some or all the associated transactional data visible. A smart contract form viewer can be used to view and interact with a smart contract form linked to the smart contract. The smart contract form can present contractual provisions in natural language, present transactional data to an authorized user, and accept entry or validation of designated transaction data.