Abstract: A gamut size metric is used in all phases of color image processing (e.g., capture, transmission, and display). In general, the gamut size metric is a single-valued metric that changes as image content changes. More particularly, a gamut boundary histogram is determined and used to estimate a gamut size metric. A gamut size metric identifies a minimum size gamut needed to encompass each pixel in an image, where the gamut size is limited at one end by a first device independent gamut (S1), and at another end by a second device independent color space (S2), where S1 is wholly enclosed within S2. The gamut size metric may be based on strict pixel color value differences. In other embodiments the gamut size metric may take into effect perceptual color differences and significance.

Abstract: Techniques for auto white balancing of captured images based on detection of flicker in ambient light is described. When flicker is detected in ambient light during an image capture event, and the flicker is unchanging during the image capture event, a white point of image data may be estimated according to a first technique. When flicker is detected in ambient light during an image capture event, and the flicker is changing during the image capture event, a white point of image data may be estimated according to a second technique. When flicker is not detected, a white point of image data may be estimated according to a third technique. Image data may be color corrected based on the estimated white point.

Abstract: Methods, devices and computer readable instructions to generate region-of-interest (ROI) tone curves are disclosed. One method includes obtaining a statistic for an entire image such as, for example, a luminance statistic. The same statistic may then be found for a specified ROI of the image. A weighted combination of the statistic of the entire image and the statistic of the ROI yields a combined statistic which may then be converted to a ROI-biased tone curve. The weight used to combine the two statistics may be selected to emphasize or de-emphasize the role of the ROI's statistic in the final tone curve.

Abstract: A composition of goserelin sustained release microspheres is provided. The microspheres comprise goserelin, at least one poly (lactide-co-glycolide) and poloxamer or PEG. The sustained release microspheres have comparatively high bioavailability, which promotes the drug taking its full effect and have entrapment efficiency over 90%.

Abstract: This disclosure relates to a wide gamut encoder capable of receiving a wide gamut color image in accordance with a wide gamut standard. The encoder can encode one or more wide gamut color image pixel values into portions of narrow gamut encoding elements for transmission to a video encoder. The encoder can implement an advanced extended YCC format that is backward compatible with a P3 color gamut.

Abstract: Image enhancement is achieved by separating image signals, e.g. YCbCr image signals, into a series of frequency bands and performing locally-adaptive noise reduction on bands below a given frequency but not on bands above that frequency. The bands are summed to develop the image enhanced signals. The YCbCr, multi-band locally-adaptive approach to denoising is able to operate independently—and in an optimized fashion—on both luma and chroma channels. Noise reduction is done based on models developed for both luma and chroma channels by measurements taken for multiple frequency bands, in multiple patches on the ColorChecker chart, and at multiple gain levels, in order to develop a simple yet robust set of models that may be tuned off-line a single time for each camera and then applied to images taken by such cameras in real-time without excessive processing requirements and with satisfactory results across illuminant types and lighting conditions.

Abstract: In general, techniques are disclosed for displaying wide-gamut images as intended on color-managed wide-gamut display systems while rendering a visually consistent image when rendered on targeted narrow-gamut display systems (regardless of whether the narrow-gamut displays are color-managed). For this reason, an image represented in accordance with this disclosure is referred to as a dual-target image (DTI): one target being the image's original wide-gamut color space, the other target being a specified narrow-gamut color space. The novel representational scheme described herein retains narrow-gamut rendering for those colors in a wide-gamut image that are within the targeted narrow-gamut color space, transitioning to wide-gamut rendering for those colors in the wide-gamut image that are outside the targeted narrow-gamut color space.

Abstract: A gamut size metric for use in all phases of color image processing (e.g., capture, transmission, and display) is described. In general, techniques are disclosed for determining a single-valued metric that changes as image content changes. More particularly, techniques disclosed herein may be used to efficiently determine a gamut boundary histogram which may be used to estimate a gamut size metric. A gamut size metric as disclosed herein identifies a minimum size gamut needed to encompass each pixel in an image, where the gamut size is limited at one end by a first device independent gamut (S1), and at another end by a second device independent color space (S2), where S1 is wholly enclosed within S2. The described gamut size metric may be based on strict pixel color value differences. In other embodiments the gamut size metric may take into effect perceptual color differences and significance.

Abstract: Methods, devices and computer readable instructions to generate multi-scale tone curves are disclosed. One method includes finding, for a given input image, a global tone curve that exhibits monotonic behavior. The input image may then be partitioned into a first number of sub-regions. For each sub-region, a local tone curve may be determined that has an output level that is constrained to the global tone curve at one or more first luminance levels so that each sub-region's local tone curve's output follows the global tone curve's monotonic behavior. If the resulting local tone curves provide sufficient control of shadow-boost, highlight-suppression, and contrast optimization the first number of local tone curves may be applied directly to the input image. If additional control is needed, each sub-region may again be partitioned and local tone curves determined for each of the new sub-regions.

Abstract: Methods, devices and computer readable instructions to generate region-of-interest (ROI) tone curves are disclosed. One method includes obtaining a statistic for an entire image such as, for example, a luminance statistic. The same statistic may then be found for a specified ROI of the image. A weighted combination of the statistic of the entire image and the statistic of the ROI yields a combined statistic which may then be converted to a ROI-biased tone curve. The weight used to combine the two statistics may be selected to emphasize or de-emphasize the role of the ROI's statistic in the final tone curve.

Abstract: Systems, methods, and computer readable media for the use of a metric whose value is especially sensitive to the information lost when an image's pixels are clipped are disclosed. The metric may be used as an image's score, where higher values are indicative of lost highlight information (more clipped pixels). One use of the disclosed metric would be to determine when the use of high dynamic range (HDR) techniques are appropriate. The disclosed metric may also be used to bias a scene's exposure value (EV) such as to a lower or underexposed value (EV?) so that the scene may be captured with no more than an acceptable number of clipped pixels.

Abstract: An image sensor device has a first region configured to sense only infrared illumination and a second region configured to not sense visible and infrared illumination.

Abstract: Systems, methods, and computer readable media to capture and process high dynamic range (HDR) images when appropriate for a scene are disclosed. When appropriate, multiple images at a single—slightly underexposed—exposure value are captured (making a constant bracket HDR capture sequence) and local tone mapping (LTM) applied to each image. Local tone map and histogram information can be used to generate a noise-amplification mask which can be used during fusion operations. Images obtained and fused in the disclosed manner provide high dynamic range with improved noise and de-ghosting characteristics.

Abstract: Methods, devices and computer readable instructions to generate multi-scale tone curves are disclosed. One method includes finding, for a given input image, a global tone curve that exhibits monotonic behavior. The input image may then be partitioned into a first number of sub-regions. For each sub-region, a local tone curve may be determined that has an output level that is constrained to the global tone curve at one or more first luminance levels so that each sub-region's local tone curve's output follows the global tone curve's monotonic behavior. If the resulting local tone curves provide sufficient control of shadow-boost, highlight-suppression, and contrast optimization the first number of local tone curves may be applied directly to the input image. If additional control is needed, each sub-region may again be partitioned and local tone curves determined for each of the new sub-regions.

Abstract: Image enhancement is achieved by separating image signals, e.g. YCbCr image signals, into a series of frequency bands and performing locally-adaptive noise reduction on bands below a given frequency but not on bands above that frequency. The bands are summed to develop the image enhanced signals. The YCbCr, multi-band locally-adaptive approach to denoising is able to operate independently—and in an optimized fashion—on both luma and chroma channels. Noise reduction is done based on models developed for both luma and chroma channels by measurements taken for multiple frequency bands, in multiple patches on the ColorChecker chart, and at multiple gain levels, in order to develop a simple yet robust set of models that may be tuned off-line a single time for each camera and then applied to images taken by such cameras in real-time without excessive processing requirements and with satisfactory results across illuminant types and lighting conditions.

Abstract: A solid state imaging device includes an array of active pixels and an infrared cut filter formed over the sensor. Optionally, a slot in the infrared cut filter allows infrared illumination to reach the sensor to be detected by pixels covered by a visually opaque filter and surrounded by pixels of special types that limit charge leakage and enable high dynamic range sensing of infrared illumination. A ratio of average infrared signal to average brightness indicates an amount of infrared illumination reaching the imaging device.

Abstract: A composition of goserelin sustained release microspheres is provided. The microspheres comprise goserelin, at least one poly(lactide-co-glycolide) and poloxamer or PEG. The sustained release microspheres have comparatively high bioavailability, which promotes the drug taking its full effect and have entrapment efficiency over 90%.

Abstract: Systems, methods, and computer readable media for the use of a metric whose value is especially sensitive to the information lost when an image's pixels are clipped are disclosed. The metric may be used as an image's score, where higher values are indicative of lost highlight information (more clipped pixels). One use of the disclosed metric would be to determine when the use of high dynamic range (HDR) techniques are appropriate. The disclosed metric may also be used to bias a scene's exposure value (EV) such as to a lower or underexposed value (EV?) so that the scene may be captured with no more than an acceptable number of clipped pixels.

Abstract: Systems, methods, and computer readable media to capture and process high dynamic range (HDR) images when appropriate for a scene are disclosed. When appropriate, multiple images at a single—slightly underexposed—exposure value are captured (making a constant bracket HDR capture sequence) and local tone mapping (LTM) applied to each image. Local tone map and histogram information can be used to generate a noise-amplification mask which can be used during fusion operations. Images obtained and fused in the disclosed manner provide high dynamic range with improved noise and de-ghosting characteristics.

Abstract: The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.