Patents by Inventor Xueming Qian

Xueming Qian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC HUMAN ANTI-IL-1R1 MONOCLONAL ANTIBODY
    Publication number: 20120269824
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Application
    Filed: April 18, 2012
    Publication date: October 25, 2012
    Applicants: Medarex, Inc., Amgen Inc.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Therapeutic human anti-IL-1R1 monoclonal antibody
    Patent number: 8236559
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: August 7, 2012
    Assignees: Medarex, Inc., Amgen Inc.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • SINGLE MATCHING NETWORK FOR MATCHING MULTI-FREQUENCY AND METHOD OF CONSTRUCTURING THE SAME AND RADIO FREQUENCY POWER SOURCE SYSTEM USING THE SAME
    Publication number: 20120075033
    Abstract: A single matching network is adapted to input at least two frequencies, which is used to selectively provide an RF power match at any one of the at least two frequencies to a plasma load, and the single matching network includes an input terminal connected to a multi-frequency input and an output terminal connected to the plasma load. A capacitor and an inductor connected in series with each other are provided between the input terminal and the output terminal to form a branch, the capacitance value of the capacitor is C0, and the inductance value of the inductor is Lo, wherein, the capacitance value C0 and the inductance value L0 satisfy the following relations: j?1L0+1/j?1C0=jy1 j?2L0+1/j?2C0=jy2 wherein, ?1=2?f1, ?2=2?f2, the f1 and f2 are respectively the two frequencies, y1 is the impedance required for the branch when achieving a matching state at frequency f1, and y2 is the impedance required for the branch when achieving a matching state at frequency f2.
    Type: Application
    Filed: September 21, 2011
    Publication date: March 29, 2012
    Inventors: Liang OUYANG, Lei Liu, Xueming Qian, Jinyuan Chen
  • WISE BINDING AGENTS AND EPITOPES
    Publication number: 20120003237
    Abstract: The present invention relates to binding agents for WISE, and includes for their manufacture and use.
    Type: Application
    Filed: September 15, 2011
    Publication date: January 5, 2012
    Applicant: AMGEN INC.
    Inventors: Xueming QIAN, Kevin Graham, Grant Shimamoto, Barbara S. Tipton, Mei-Mei Tsai, Aaron George Winters, Li Zhang
  • Wise binding agents and epitopes
    Patent number: 8043620
    Abstract: The present invention relates to binding agents for WISE, and includes for their manufacture and use.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: October 25, 2011
    Assignee: Amgen Inc.
    Inventors: Xueming Qian, Kevin Graham, Grant Shimamoto, Barbara S. Tipton, Mei-Mei Tsai, Aaron George Winters, Li Zhang
  • Therapeutic Human Anti-IL-1R1 Monoclonal Antibody
    Publication number: 20090214559
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Application
    Filed: September 15, 2008
    Publication date: August 27, 2009
    Applicants: AMGEN, INC., MEDAREX INC.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • WISE BINDING AGENTS AND EPITOPES
    Publication number: 20090130114
    Abstract: The present invention relates to binding agents for WISE, and includes for their manufacture and use.
    Type: Application
    Filed: November 21, 2008
    Publication date: May 21, 2009
    Inventors: Xueming Qian, Kevin Graham, Grant Shimamoto, Barbara S. Tipton, Mei-Mei Tsai, Aaron George Winters, Li Zhang
  • Therapeutic human anti-IL1-R1 monoclonal antibody
    Patent number: 7438910
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: October 21, 2008
    Assignees: Amgen Inc., Medarex, Inc.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Screening method for antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof
    Publication number: 20050084493
    Abstract: The invention concerns methods of treating IL-1-mediated disease by administering a selective IL-1 binding agents that form an antagonist complex with the IL-1 ligand. The antagonist complex can bind to the IL-1 receptor without activating the receptor. The selective binding agents contemplated by this invention thus have the properties of free ligand absorption (through binding of the selective binding agent to free IL-1? or ?) and receptor activation inhibition (through binding of the antagonist complex to the receptor and preventing its activation).
    Type: Application
    Filed: November 9, 2004
    Publication date: April 21, 2005
    Inventors: Alison Witte, Brian Varnum, Xueming Qian, Chris Vezina
  • Therapeutic human anti-IL1-R1 monoclonal antibody
    Publication number: 20040097712
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Application
    Filed: September 5, 2003
    Publication date: May 20, 2004
    Applicant: Amgen, Inc. A Corporation of the State of Delaware
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof
    Publication number: 20030026806
    Abstract: The invention concerns methods of treating IL-1-mediated disease by administering a selective IL-1 binding agents that form an antagonist complex with the IL-1 ligand. The antagonist complex can bind to the IL-1 receptor without activating the receptor. The selective binding agents contemplated by this invention thus have the properties of free ligand absorption (through binding of the selective binding agent to free IL-1&agr; or &bgr;) and receptor activation inhibition (through binding of the antagonist complex to the receptor and preventing its activation).
    Type: Application
    Filed: October 29, 2001
    Publication date: February 6, 2003
    Applicant: Amgen Inc.
    Inventors: Alison Witte, Brian C. Varnum, Xueming Qian, Chris Vezina