Abstract: The present invention belongs to the medical field, and relates to novel ?-lactamase inhibitors, for the treatment of bacterial infections in combination with ?-lactam antibiotics, including infection caused by drug resistant organisms and especially multi-drug resistant organisms. The present invention includes compounds according to formula (I): or pharmaceutically acceptable salts thereof, wherein M and R are as defined herein.

Abstract: The present invention provides a catalytic cracking catalyst for heavy oil and preparation methods thereof. The catalyst comprises 2 to 50% by weight of a phosphorus-containing ultrastable rare earth Y-type molecular sieve, 0.5 to 30% by weight of one or more other molecular sieves, 0.5 to 70% by weight of clay, 1.0 to 65% by weight of high-temperature-resistant inorganic oxides, and 0.01 to 12.5% by weight of a rare earth oxide. The phosphorus-containing ultra-stable rare earth Y-type molecular sieve uses a NaY molecular sieve as a raw material.

Abstract: The present invention provides a catalytic cracking catalyst for heavy oil and preparation methods thereof. The catalyst comprises 2 to 50% by weight of a phosphorus-containing ultrastable rare earth Y-type molecular sieve, 0.5 to 30% by weight of one or more other molecular sieves, 0.5 to 70% by weight of clay, 1.0 to 65% by weight of high-temperature-resistant inorganic oxides, and 0.01 to 12.5% by weight of a rare earth oxide. The phosphorus-containing ultra-stable rare earth Y-type molecular sieve uses a NaY molecular sieve as a raw material.

Abstract: The present disclosure provides a method, a system and a device of transmitting instant messaging information. The techniques use at least two determinations. A first determination evaluates whether a first user identification of a sender of the instant messaging information is identified as a high priority user associated with a second user identification of a receiver. A second determination ascertains whether operation information relating the second user identification corresponding to the first user identification is stored. When the result of the first determination is negative, the instant messaging information is not directly treated as instant messaging information. The result of the second determination may be used to determine whether the instant messaging information is junk information. The techniques, when achieving the purpose of filtering junk information, reduce the possibility that the valid information is treated as junk information, and improve the accuracy of filtering junk information.