Abstract: The present disclosure provides an N protein epitope mutation marker for preparing an epitope deletion-marked vaccine strain of type II porcine reproductive and respiratory syndrome virus (PRRSV) and use thereof, belonging to the technical field of biological products. In the mutation marker, one or more amino acids are mutated based on an epitope sequence at positions 92 to 103 of a C-terminal of an N protein of the type II PRRSV; and the epitope mutation marker has an amino acid sequence shown in SEQ ID NO: 1, where X1 is selected from the group consisting of T, P, and A; and X2 is selected from the group consisting of V and A.

Abstract: A dual-gas source gas control system with anti-gas source misconnection and a control circuit thereof belonging to the gas combustion technical field are provided. The disclosure solves unreasonable design and other problems in the related art. The dual-gas source gas control system with anti-gas source misconnection and the control circuit thereof includes a power-on circuit, connected in series with an external power supply and an igniter switch to form a loop, including a self-locking switch triode connected in series with the external power supply and a self-locking amplifying triode connected to a base electrode of the self-locking switch triode; an MCU control circuit, including an MCU control chip, wherein the power-on circuit is connected to a power input pin of the MCU control chip, one pin on the MCU control chip is configured to detect whether the power-on circuit is connected.

Abstract: A dual-gas source gas control system with anti-gas source misconnection and a control circuit thereof belonging to the gas combustion technical field are provided. The disclosure solves unreasonable design and other problems in the related art. The dual-gas source gas control system with anti-gas source misconnection and the control circuit thereof includes a power-on circuit, connected in series with an external power supply and an igniter switch to form a loop, including a self-locking switch triode connected in series with the external power supply and a self-locking amplifying triode connected to a base electrode of the self-locking switch triode; an MCU control circuit, including an MCU control chip, wherein the power-on circuit is connected to a power input pin of the MCU control chip, one pin on the MCU control chip is configured to detect whether the power-on circuit is connected.

Abstract: The present invention provides methods to quickly and efficiently assess the effect of antibody variants, including PTMs, e.g., glycosylation, oxidation, and deamidation variants, on the binding between the antibody and FcRn. In particular, the present invention is based, at least in part, on the development of an online, two dimension liquid chromatography (2D-LC) method for assessing binding between antibody variants and FcRn. In one aspect, the online 2D-LC is coupled with mass spectrometry (MS). The present invention allows for differentiation of antibody variants by peak pattern and retention time profile by affinity chromatography, and identification of these variants by mass spectrometry analysis.

Abstract: The present invention provides a dual fuel ignition device and a work method thereof, wherein the ignition device can output electric potential according to the opposite in-series connection of two thermocouples in a high-heating value gas igniting end and a low-heating value gas igniting end and the heating condition of the thermocouples, and can control the switching on or off of a control valve on a gas flow according to the effective heat electric potential generated by the thermocouples in the process of ignition, so as to avoid the danger condition that the main burner generates high fire caused by the misoperation of the gas appliance, therefore, the safe use can be guaranteed.

Abstract: The present invention provides a dual fuel ignition device and a work method thereof, wherein the ignition device can output electric potential according to the opposite in-series connection of two thermocouples in a high-heating value gas igniting end and a low-heating value gas igniting end and the heating condition of the thermocouples, and can control the switching on or off of a control valve on a gas flow according to the effective heat electric potential generated by the thermocouples in the process of ignition, so as to avoid the danger condition that the main burner generates high fire caused by the misoperation of the gas appliance, therefore, the safe use can be guaranteed.