Abstract: A display substrate, a manufacturing method therefor, and a display apparatus are disclosed. The display substrate includes a display area (100), a bonding area (200) and a bezel area (300). On a plane perpendicular to the display substrate, the display substrate includes a base substrate (101) and a driving circuit layer (102). The substrate (101) at least includes a base conductive layer disposed between a first flexible layer (10A) and a second flexible layer (10C), the base conductive layer at least includes a first connection line (70), the driving circuit layer (102) at least includes a data signal line (60) and a second connection line (80), the second connection line (80) is connected to the first connection line (70) through a first lapping via (DV1), the data signal line (60) is connected to the second connection line (80) through a second lapping via (DV2).

Abstract: Disclosed is a display panel, comprising a display region. The display panel further comprises a first flexible substrate, a second flexible substrate, and multiple first data lines. The display panel further comprises multiple pixel driving circuits and multiple second data lines located in the display region; the multiple pixel driving circuits are arranged in an array; the multiple first data lines comprise wiring portions in the column direction of the array of the pixel driving circuits; each pixel driving circuit comprises a driving transistor; and the orthographic projection of at least the wiring portions of the multiple first data lines in the column direction of the array of the pixel driving circuits on the first flexible substrate does not overlap with the orthographic projection of channel regions of the driving transistors on the first flexible substrate.

Abstract: A display substrate is provided, including: a base substrate and a plurality of sub-pixels disposed on the base substrate. Each sub-pixel includes a pixel driving circuit, and the pixel driving circuit includes a writing transistor, a compensation transistor, a first reset transistor, and a storage capacitor. The display substrate includes a semiconductor layer, a first conductive layer and a second conductive layer disposed in sequence on the base substrate. Gates of the writing transistor, the compensation transistor and the first reset transistor are in the first conductive layer and are implemented as an integral structure. Active layers of the writing transistor, the compensation transistor and the first reset transistor are in the semiconductor layer. A first storage capacitor electrode of the storage capacitor is in the first conductive layer, and a second storage capacitor electrode of the storage capacitor is in the second conductive layer.

Abstract: A display substrate includes a substrate, scan signal lines, a plurality of first pixel circuits and a plurality of first light-emitting devices. The plurality of first pixel circuits are disposed on the substrate, and are located in a functional device setting region. At least one first pixel circuit includes a first transistor. At least one first light-emitting device includes a first electrode. The at least one first light-emitting device includes at least one first color light-emitting device, and the at least one first pixel circuit includes at least one first color pixel circuit, and a first color pixel circuit is electrically connected to a first color light-emitting device. An orthographic projection of a channel region of a first transistor in the first color pixel circuit on the substrate is at least partially overlapped with an orthographic projection of a first electrode of the first color light-emitting device on the substrate.

Abstract: A human activity recognition fusion method and system for ecological protection red line is disclosed. The method includes: obtaining a pre-stage remote sensing image and a post-stage remote sensing image of a target ecological protection red line region, and performing a data pre-processing; inputting the pre-processed pre-stage remote sensing image and the post-stage remote sensing image into a human activity recognition model after a pre-training; identifying a human activity pattern of the target ecological protection red line region as a first detection result; segmenting, calculating and analyzing the latest image data corresponding to the target ecological protection red line region based on a geographical country situation data to obtain a change pattern as a second detection result; and fusing the first detection result and the second detection result to obtain a change detection pattern of the target ecological protection red line region.

Abstract: In some embodiments, a method determines feature values for a portion of a video and a target configuration. The target configuration is associated with a parameter of an encoder and includes a set of bitrates and a resolution. A plurality of quality values is generated for the set of bitrates and the resolution based on the feature values. The method generates a representation of a relationship between bitrate and the plurality of quality values for the resolution. The representation is analyzed to determine a list of bitrates for the portion of the video. The method outputs he list of bitrates for use encoding the portion of the video using the resolution.

Abstract: A display apparatus includes a driving chip, a flexible circuit board and a display panel. The display panel includes a display portion and a bonding portion on one side of the display portion, and the bonding portion includes a first bending portion, a first connection portion, a second bending portion and a second connection portion which are sequentially arranged in a direction with an increasing extending distance from the display portion. The driving chip is in bonding connection with the display panel in the first connection portion, the flexible circuit board is in bonding connection with the display panel in the second connection portion, the driving chip is disposed on a side of the first connection portion facing away from the display portion, and the flexible circuit board is disposed on a side of the driving chip facing away from the display portion.

Abstract: Provided is a display substrate. The display substrate includes including a base substrate having a first display region and a second display region; in the pixel circuit included in the pixels in the second display region, the conductive line connected to the metal layer is a transparent conductive line, and the transparent conductive line is disposed between the two existing insulating layers.

Abstract: The present invention provides a fusion cage. The fusion cage includes a first end surface, designed to conform to and support human tissue. The first end surface is provided with a first lattice structure extending into the interior of the fusion cage. The first lattice structure is intended to conform to and support human tissue, providing a pathway for bone ingrowth into the interior of the fusion cage. A second lattice structure is provided within the fusion cage, serving to reduce the overall product's elastic modulus and provide space for bone ingrowth. The primary purpose of the first lattice structure is to offer a space for the growth of human tissue, and the combined action of both lattice structures at two locations helps address the technical challenge of prior art being unable to simultaneously meet the matching bone elastic modulus and aid in the growth of human tissue.

Abstract: The present invention discloses a fusion cage. The fusion cage includes a first end surface and a second end surface. The first end surface is provided with a first lattice, and at least one region of the second end surface is provided with a second lattice. The first lattice provides a pathway for attaching and supporting human tissue, facilitating inward bone ingrowth for the fusion cage. The structure of the second lattice is designed to decrease the overall elastic modulus of the product and provide a region for bone ingrowth. Different lattice layouts, with the first lattice facilitating inward bone ingrowth and the second lattice reducing bone elastic modulus, address the issue in existing fusion devices of not meeting both bone elastic modulus matching and human tissue growth simultaneously.

Abstract: A display substrate, a preparing method therefor, and a display apparatus are disclosed. The display substrate includes a display region (100), the display region (100) includes a plurality of sub-pixels, at least one sub-pixel includes a circuit unit disposed on the base substrate (101), the circuit unit at least includes a pixel drive circuit and a data signal line (60), the pixel drive circuit is connected with the data signal line (60); the base substrate (101) includes a base substrate conductive layer disposed between the first flexible layer (101A) and the second flexible layer (101C), the base substrate conductive layer at least includes a data fan-out line (70), and the data signal line (60) is connected with the data fan-out line (70) through a lapping via (DV1).

Abstract: Co-crystals comprising the Nuclear receptor related 1 protein-ligand binding domain (Nurr1-LBD) and a cyclopentenone prostaglandin are provided. Also provided are methods of identifying or designing Nurr1-modulating ligands and compounds based on the crystal structures described herein as well as the applications of said ligands and compounds as Nurr1 modulators or medicaments.

Abstract: A drug for antagonizing the replication of porcine reproductive and respiratory syndrome virus (PRRSV) and an application thereof. By using a viral infection test, a drug which antagonizes PRRSV—xanthohumol—is discovered for the first time from among a natural drug library of 386 plant sources. Xanthohumol can effectively inhibit PRRSV replication on both Marc-145 and PAM cells. Five xanthohumol derivatives having different molecular structures are artificially synthesized, and it is discovered that a derivative Xn-4 has the strongest inhibitory effect on virus replication in vitro. Test results of artificial infection and drug therapy in piglets show that the Xn-4 can effectively inhibit PRRSV viremia, relieve clinical symptoms of infected pigs, and significantly reduce lung inflammation and pathological damage.

Abstract: The present application provides an optical fibre grating sensor and a strain monitoring method and system for a surrounding rock of a deep roadway, which are used for monitoring deformation of the surrounding rock of the deep roadway and are provided with a weak optical fibre grating array large-range strain sensor, which can accurately monitor the strain of the surrounding rock of the deep roadway. The optical fibre grating sensor comprises an optical fibre, the optical fibre comprises an optical fibre core and a plurality of optical fibre gratings inscribed on the optical fibre core, the optical fibre grating is a weak optical fibre grating with a peak reflectivity lower than 1%, and the plurality of optical fibre gratings perform unit discretization on the whole piece of the optical fibre so as to realize quasi-distributed sensing.

Abstract: The present application provides an optical fibre grating sensor and a strain monitoring method and system for a surrounding rock of a deep roadway, which are used for monitoring deformation of the surrounding rock of the deep roadway and are provided with a weak optical fibre grating array large-range strain sensor, which can accurately monitor the strain of the surrounding rock of the deep roadway. The optical fibre grating sensor comprises an optical fibre, the optical fibre comprises an optical fibre core and a plurality of optical fibre gratings inscribed on the optical fibre core, the optical fibre grating is a weak optical fibre grating with a peak reflectivity lower than 1%, and the plurality of optical fibre gratings perform unit discretization on the whole piece of the optical fibre so as to realize quasi-distributed sensing.

Abstract: An adaptor plate includes a front plate that is configured to span across at least a portion of a front of an electrical junction box and includes one or more adaptor plate mounting features configured to align with corresponding mounting features of the electrical junction box. A DIN rail engagement portion extends backward from the front plate (and into the junction box) and is configured to fit at least partially into an elongated DIN rail mounting recess of a DIN rail device. In some cases, a first mounting slot is disposed within a first side of the DIN rail engagement portion for receiving a first mounting latch of the DIN rail device, and a second mounting slot is disposed within a second side of the DIN rail engagement portion for receiving a second mounting latch of the DIN rail device.

Abstract: Co-crystals comprising the Nuclear receptor related 1 protein-ligand binding domain (Nurr1-LBD) and a cyclopentenone prostaglandin are provided. Also provided are methods of identifying or designing Nurr1-modulating ligands and compounds based on the crystal structures described herein as well as the applications of said ligands and compounds as Nurr1 modulators or medicaments.

Abstract: Co-crystals comprising the Nuclear receptor related 1 protein-ligand binding domain (Nurr1-LBD) and a cyclopentenone prostaglandin are provided. Also provided are methods of identifying or designing Nurr1-modulating ligands and compounds based on the crystal structures described herein as well as the applications of said ligands and compounds as Nurr1 modulators or medicaments.

Abstract: The invention relates to a compound of formula Ia and/or formula Ib: or a pharmaceutically acceptable salt, solvate or prodrug thereof, where the groups are defined herein. The invention also relates to a pharmaceutical formulation comprising the compound for treating or detecting a microbial infection in a subject, a method of determining antimicrobial resistance of a microbial infection using the compound, and a method of determining an effective dose of one or more antimicrobial agents to kill a microorganism using the compound.