Patents by Inventor Xueyong Zhu

Xueyong Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEIN M RELATED IMMUNOGLOBULIN-BINDING POLYPEPTIDES
    Publication number: 20170320921
    Abstract: The invention relates to a group of isolated polypeptides and derivatives that can bind genetically to immunoglobulins or antibodies. The invention also relates to industrial and other applications of these molecules, e.g., antibody purifications.
    Type: Application
    Filed: February 2, 2015
    Publication date: November 9, 2017
    Inventors: Rajesh Grover, Richard Lerner, Ian Wilson, Xueyong Zhu
  • Immunoglobulin-binding human mycoplasma antigens and methods of use thereof
    Patent number: 9593150
    Abstract: Provided herein methods of alleviating the symptoms of multiple myeloma in a patient or subject in need thereof, methods of treating multiple myeloma in a patient or subject, and methods of preventing development of multiple myeloma in a patient at risk thereof, such as a patient with monoclonal gammopathy of undetermined significance (MGUS), which methods include administering an agent effective to treat a Mycoplasma infection. The invention also relates to a new class of antigen, MG281 protein {also referenced as Protein M), that binds to various immunoglobulins with high affinity, and their uses in purifying immunoglobulins. The invention additionally relates to using MG281 protein and analog or derivative molecules for treating autoimmune diseases. Further provided are antigens and antibodies for use in the disclosed methods, and the identification of molecules that bind to MG281 protein.
    Type: Grant
    Filed: July 16, 2013
    Date of Patent: March 14, 2017
    Assignee: The Scripps Research Institute
    Inventors: Rajesh Grover, Richard Lerner, Ian Wilson, Xueyong Zhu
  • IMMUNOGLOBULJIN-BINDING HUMAN MYCOPLASMA ANTIGENS AND METHODS OF USE THEREOF
    Publication number: 20150246953
    Abstract: Provided herein methods of alleviating the symptoms of multiple myeloma in a patient or subject in need thereof, methods of treating multiple myeloma in a patient or subject, and methods of preventing development of multiple myeloma in a patient at risk thereof, such as a patient with monoclonal gammopathy of undetermined significance (MGUS), which methods include administering an agent effective to treat a Mycoplasma infection. The invention also relates to a new class of antigen, MG281 protein {also referenced as Protein M), that binds to various immunoglobulins with high affinity, and their uses in purifying immunoglobulins. The invention additionally relates to using MG281 protein and analog or derivative molecules for treating autoimmune diseases. Further provided are antigens and antibodies for use in the disclosed methods, and the identification of molecules that bind to MG281 protein.
    Type: Application
    Filed: July 16, 2013
    Publication date: September 3, 2015
    Inventors: Rajesh Grover, Richard Lerner, Ian Wilson, Xueyong Zhu