Patents by Inventor Xuezhen XU

Xuezhen XU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240018079
    Abstract: Disclosed is a method for purifying cannabinoid compounds that enables cannabinoid compounds to be obtained more economically and with a better purification effect.
    Type: Application
    Filed: November 25, 2021
    Publication date: January 18, 2024
    Inventors: Yi SUN, Xuezhen XU, Jing ZHANG, Yonggang WEI
  • Publication number: 20230227482
    Abstract: Tetrahydrocannabinol derivatives and medical use thereof, in particular to the compounds represented by general formula (I), or stereoisomers, solvates, metabolites, pharmaceutically acceptable salts or cocrystals thereof, wherein the definitions of substituents in general formula (I) are the same as those in the description
    Type: Application
    Filed: January 7, 2021
    Publication date: July 20, 2023
    Inventors: Jing ZHANG, Xuezhen XU, Yonggang WEI, Hongzhu CHU, Fuqiang ZHAO, Guizhuan SU, Meiwei WANG, Yi SUN
  • Publication number: 20230165867
    Abstract: The present application relates to imidazolidinone derivatives and medical use thereof, and in particular relates to pyrimidine derivatives represented by general formula (I), or stereoisomers, solvates, metabolites, prodrugs, pharmaceutically acceptable salts or co-crystals thereof, a pharmaceutical composition comprising the same, and use of the compound or pharmaceutical composition according to the present application in the manufacture of a medicament for treatment of cancer.
    Type: Application
    Filed: October 14, 2022
    Publication date: June 1, 2023
    Inventors: Yonggang WEI, Xuezhen XU, Hongzhu CHU, Lvxue HE, Feiquan LEI, Jie YAN, Yang HE, Meiwei WANG, Guizhuan SU, Bing LIU, Yi SUN
  • Publication number: 20230059087
    Abstract: Cannabidiol derivatives and medical use thereof, in particular to the compounds represented by general formula (I), or stereoisomers, solvates, metabolites, prodrugs, pharmaceutically acceptable salts or cocrystals thereof, wherein the definitions of substituents in general formula (I) are the same as those in the description
    Type: Application
    Filed: January 7, 2021
    Publication date: February 23, 2023
    Inventors: Xibing ZHOU, Jing ZHANG, Xuezhen XU, Yonggang WEI, Hongzhu CHU, Fuqiang ZHAO, Guizhuan SU, Meiwei WANG, Yi SUN
  • Publication number: 20230002425
    Abstract: Cannabidiol derivatives and medical use thereof, in particular to compounds represented by general formula (I), or stereoisomers, solvates, metabolites, pharmaceutically acceptable salts or cocrystals thereof, wherein the definitions of the substituents in general formula (I) are the same as those in the description.
    Type: Application
    Filed: January 7, 2021
    Publication date: January 5, 2023
    Inventors: Xuezhen XU, Jing ZHANG, Yonggang WEI, Hongzhu CHU, Fuqiang ZHAO, Guizhuan SU, Meiwei WANG, Yi SUN
  • Publication number: 20220402920
    Abstract: The present invention relates to a purine derivative and use thereof in medicine, and in particular to a pyrimidine derivative shown as general formula (I) or a stereoisomer, solvate, metabolite, prodrug, deuteride, pharmaceutically acceptable salt or cocrystal thereof, a pharmaceutical composition comprising the same, and use of the compound or composition of the present invention in the field of preparation of a DNA-PK inhibitor, wherein the substituents in general formula (I) are defined in the same way as in the specification
    Type: Application
    Filed: December 30, 2020
    Publication date: December 22, 2022
    Inventors: Yonggang Wei, Xuezhen Xu, Hongzhu Chu, Lvxue He, Xiangyu Meng, Meiwei Wang, Guizhuan Su, Bing Liu, Yi Sun
  • Patent number: 10053443
    Abstract: The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: August 21, 2018
    Assignees: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, DONGGUK UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
    Inventors: Kyeong Lee, Sei-Ryang Oh, Kyung Seop Ahn, Ok-Kyoung Kwon, Doo-Young Kim, Hyung Won Ryu, Jung Hee Kim, Xuezhen Xu
  • Publication number: 20170174645
    Abstract: The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.
    Type: Application
    Filed: March 3, 2017
    Publication date: June 22, 2017
    Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kyeong LEE, Sei-Ryang OH, Kyung Seop AHN, Ok-Kyoung KWON, Doo-Young KIM, Hyung Won RYU, Jung Hee KIM, Xuezhen XU
  • Publication number: 20160332980
    Abstract: The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.
    Type: Application
    Filed: July 27, 2016
    Publication date: November 17, 2016
    Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kyeong LEE, Sei-Ryang OH, Kyung Seop AHN, Ok-Kyoung KWON, Doo-Young KIM, Hyung Won RYU, Jung Hee KIM, Xuezhen XU