Abstract: Provided herein is a class of a rapidly metabolized lipid compound, and particularly relates to compounds represented by formula (I?), or pharmaceutically acceptable salts, isotopic variants, tautomers, or stereoisomers thereof. Also provided is a nanoparticle pharmaceutical composition comprising said compound, and the application of said compound and its composition in the delivery of nucleic acids.

Abstract: Disclosed are a flexible pH sensor and detection system, belonging to the technical field of sensors. A material that does not react with electrolyte is mixed with metals to print an anode substrate, and one-step synthesis of a metal ions doped polyaniline composite material is realized through an electrochemical method. The doping amount of metal ions in polyaniline is changed by controlling metal content; due to addition of the metals, the conductivity of the anode substrate is improved, which is conducive to the deposition of polyaniline; such one-step method for preparing the polyaniline composite material is simpler, low in cost, and pollution-free; and compared with pure polyaniline, the sensitivity is further improved. According to the solution, this material is applied to the pH sensor for the first time, achieving a wide pH detection range (2-12) and high bending stability.

Abstract: Provided herein is a class of a rapidly metabolized lipid compound, and particularly relates to compounds represented by formula (I), or pharmaceutically acceptable salts, isotopic variants, tautomers, or stereoisomers thereof. Also provided is a nanoparticle pharmaceutical composition comprising said compound, and the application of said compound and its composition in the delivery of nucleic acids.

Abstract: Implementations of the present disclosure disclose a package structure, a fabricating method thereof, and a memory system. The package structure includes: a packaging substrate having a first surface and a second surface opposite the first surface; a semiconductor device on the first surface of the packaging substrate and coupled with the packaging substrate; and a cap layer covering the first surface and encapsulating the semiconductor device, wherein the cap layer and the packaging substrate have a total thickness in a first direction perpendicular to the first surface, and a ratio between a distance from an upper surface of the cap layer to an upper surface of the semiconductor device in the first direction and the total thickness satisfies a first preset value.

Abstract: The present disclosure provides a wire bonding apparatus, a wire bonding method and a semiconductor device. The wire bonding apparatus includes: a wire tube for containing the wire and including a wire exit; a wire heating assembly located at a side of the wire exit; and a pre-shaping assembly located at a side of the wire tube and including a wire pre-pressing face; the pre-shaping assembly having a first state in which the wire pre-pressing face of the pre-shaping assembly is configured to abut the wire tube and a second state in which the pre-shaping assembly is configured to disengage from the wire tube. The wire bonding apparatus, the wire bonding method and the semiconductor device as provided in the present disclosure can reduce or eliminate the cratering effect.

Abstract: Disclosed are a flexible pH sensor and detection system, belonging to the technical field of sensors. A material that does not react with electrolyte is mixed with metals to print an anode substrate, and one-step synthesis of a metal ions doped polyaniline composite material is realized through an electrochemical method. The doping amount of metal ions in polyaniline is changed by controlling metal content; due to addition of the metals, the conductivity of the anode substrate is improved, which is conducive to the deposition of polyaniline; such one-step method for preparing the polyaniline composite material is simpler, low in cost, and pollution-free; and compared with pure polyaniline, the sensitivity is further improved. According to the solution, this material is applied to the pH sensor for the first time, achieving a wide pH detection range (2-12) and high bending stability.

Abstract: The present application provides a chip package device and a memory system. The chip package device includes: a circuit substrate having a first surface and a second surface disposed oppositely, wherein the circuit substrate includes an opening that penetrates through the circuit substrate in a direction from the first substrate towards the second surface; a first chip; a second chip, wherein the second chip is fixed on the first surface of the circuit substrate, and the first chip is fixed on a surface of the second chip far away from the circuit substrate; a first conductive assembly connecting the first chip and the circuit substrate; and a second conductive assembly, wherein a part of the second conductive assembly penetrates through the opening, and the second conductive assembly connects the second chip and the circuit substrate.

Abstract: This disclosure relates to a lipid-based topical injection formulation containing a Long-Acting SusTained delivering lipid, a structured lipid, a polymer-conjugated lipid and an ionizable lipid, and optionally a neutral phospholipid. The lipid-based topical injection formulation enables enriched delivery of drugs at an injection site and efficient expression of proteins for a prolonged period of time. This disclosure also relates to a method of preparing the lipid-based topical injection formulation, and use of the lipid-based topical injection formulation in the delivery of biologically active substances such as nucleic acids (e.g., mRNA, miRNA, siRNA, saRNA, ASO, DNA, etc.).

Abstract: Within a particular Top Level Domain (TLD), domain name allocation and domain name ownership may be subject to certain restrictions requiring verification. A processing platform and method is disclosed to process verification of a domain name and/or a domain name entity such as a registrant for domain name transactions with a domain name registry. The processing platform and domain name registry may be remotely located relative to one another.

Abstract: Disclosed are a storage apparatus, a mobile terminal and an image processing method thereof. The image processing method comprises the following steps: acquiring a feature index parameter of each image; acquiring an operation instruction, and classifying images according to the operation instruction; determining, according to the classification of the images, whether a user is satisfied with an image; and if it is determined that the user is satisfied with the image, correcting a photographing parameter of a camera of a mobile terminal according to a feature index parameter of the satisfactory image, such that an image photographed thereby better conforms to the requirements of the user. Therefore, the present invention can directly obtain an image that a user is satisfied with, thereby saving on the screening time for a user, and thus improving the user experience.

Abstract: A locating method and device, and a computer storage medium are provided for realizing that an anchor node apparatus locates a beacon apparatus in a range of 360 degrees. The method is applied to an anchor node apparatus. The anchor node apparatus comprises at least three first antennas, wherein a set location of at least one first antenna is not collinear with set locations of the remaining first antennas. The method comprises: receiving a signal sent by a second antenna of a beacon apparatus by means of each of the first antennas; according to a phase of each of the first antennas for receiving the signal, obtaining a phase difference between every two first antennas for receiving the signal; extracting at least three phase differences closest to a pointed orientation; and based on the at least three phase differences, determining the orientation of the beacon apparatus.

Abstract: Within a particular Top Level Domain (TLD), domain name allocation and domain name ownership may be subject to certain restrictions requiring verification. A processing platform and method is disclosed to process verification of a domain name and/or a domain name entity such as a registrant for domain name transactions with a domain name registry. The processing platform and domain name registry may be remotely located relative to one another.

Abstract: Within a particular Top Level Domain (TLD), domain name allocation and domain name ownership may be subject to certain restrictions requiring verification. A processing platform and method is disclosed to process verification of a domain name and/or a domain name entity such as a registrant for domain name transactions with a domain name registry. The processing platform and domain name registry may be remotely located relative to one another.

Abstract: Disclosed are a storage apparatus, a mobile terminal and an image processing method thereof. The image processing method comprises the following steps: acquiring a feature index parameter of each image; acquiring an operation instruction, and classifying images according to the operation instruction; determining, according to the classification of the images, whether a user is satisfied with an image; and if it is determined that the user is satisfied with the image, correcting a photographing parameter of a camera of a mobile terminal according to a feature index parameter of the satisfactory image, such that an image photographed thereby better conforms to the requirements of the user. Therefore, the present invention can directly obtain an image that a user is satisfied with, thereby saving on the screening time for a user, and thus improving the user experience.

Abstract: An antenna control method, communications positioning apparatus and computer storage medium is provided. The method is used in a communications positioning apparatus. The communications positioning apparatus comprises a communications antenna and a rotation device. The communications antenna comprises at least two antennas. The rotation device drives the communications antenna to rotate, wherein the method comprises: acquiring a first command, wherein the first command turns on a positioning mode; in response to the first command, acquiring angle information corresponding to the communications antenna and a beacon; in accordance with the angle information, determining corresponding rotation parameters of the rotation device, wherein the rotation parameters comprise at least a rotation direction and a rotation angle; and in accordance with the rotation parameters, controlling the rotation device to drive the rotation direction and rotation angle corresponding to the communications antenna.