Patents by Inventor Xuke Li

Xuke Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240368168
    Abstract: The present invention provides an application of an SARM1 enzyme activity inhibitor in the treatment of neurodegenerative diseases or neurological diseases or conditions. The present invention particularly provides a compound of formula I as an SARM1 enzyme activity inhibitor and a pharmaceutical composition thereof.
    Type: Application
    Filed: August 25, 2022
    Publication date: November 7, 2024
    Applicant: ARTIVILA BIOPHARMA
    Inventors: Deqiang NIU, Zhendong ZHU, Ming FAN, Xuke LI
  • Patent number: 12051677
    Abstract: A front-mounted high-voltage LED light source for supplementing light to plants includes a substrate, a high-voltage LED chip set, a first layer of glue powder and a second layer of glue powder. By controlling a weight ratio of the transparent adhesive medium and the red fluorescent particles in the first layer of glue powder, as well as thickness of the first layer of glue powder; and, by controlling a weight ratio of the transparent adhesive medium and the yellow fluorescent particles in the second layer of glue powder, as well as the thickness of the second layer of glue powder, a ratio range of photon number of red light, blue light to green light emitted by the front-mounted high-voltage LED light source for supplementing light to plants per a unit time is (65-95):(5-30):(5-25).
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: July 30, 2024
    Assignee: HANGZHOU HANHUI OPTOELECTRONIC TECHNOLOGY CO., LTD.
    Inventors: Xiang Pan, Xuke Li
  • Publication number: 20230121086
    Abstract: A ROR?t inhibitor as well as a preparation method thereof and uses thereof, and a pharmaceutical composition including the compound, a method for preparing the pharmaceutical composition, and use of the compound or the pharmaceutical composition in the treatment or prevention of ROR?t-mediated cancer, inflammation, or autoimmune diseases in mammals, especially humans.
    Type: Application
    Filed: December 31, 2020
    Publication date: April 20, 2023
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Bing LIU, Yingjun ZHANG, Wei PAN, Feng WANG, Xuke LI, Wei HE, Jiuzhong HUANG
  • Patent number: 11419278
    Abstract: An upside-down type LED light source for supplemental lighting for plants includes a substrate, an LED chip, a first glue powder layer, and a second glue powder layer; the LED chip is mounted on one surface of the substrate; the LED chip being a blue LED chip; the first glue powder layer is disposed between the LED chip and the substrate, and the LED chip is covered by the second glue powder layer; the LED chip is fixed on the substrate through the first glue powder layer, wherein the first glue powder is a mixture of a glue and red phosphors; and the second glue powder layer covers the LED chip and completely wraps the LED chip; the second glue powder layer is one of a mixture of the glue and yellow phosphors, and a mixture of the glue and infrared phosphors.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: August 23, 2022
    Assignee: HANGZHOU HANHUl OPTOELECTRONIC TECHNOLOGY CO., LTD.
    Inventors: Xuke Li, Xiang Pan
  • Publication number: 20220173079
    Abstract: A front-mounted high-voltage LED light source for supplementing light to plants includes a substrate, a high-voltage LED chip set, a first layer of glue powder and a second layer of glue powder. By controlling a weight ratio of the transparent adhesive medium and the red fluorescent particles in the first layer of glue powder, as well as thickness of the first layer of glue powder; and, by controlling a weight ratio of the transparent adhesive medium and the yellow fluorescent particles in the second layer of glue powder, as well as the thickness of the second layer of glue powder, a ratio range of photon number of red light, blue light to green light emitted by the front-mounted high-voltage LED light source for supplementing light to plants per a unit time is (65-95):(5-30):(5-25).
    Type: Application
    Filed: November 1, 2019
    Publication date: June 2, 2022
    Applicant: HANGZHOU HANHUI OPTOELECTRONIC TECHNOLOGY CO., LTD.
    Inventors: Xiang PAN, Xuke LI
  • Publication number: 20210015052
    Abstract: An upside-down type LED light source for supplemental lighting for plants includes a substrate, an LED chip, a first glue powder layer, and a second glue powder layer; the LED chip is mounted on one surface of the substrate; the LED chip being a blue LED chip; the first glue powder layer is disposed between the LED chip and the substrate, and the LED chip is covered by the second glue powder layer; the LED chip is fixed on the substrate through the first glue powder layer, wherein the first glue powder is a mixture of a glue and red phosphors; and the second glue powder layer covers the LED chip and completely wraps the LED chip; the second glue powder layer is one of a mixture of the glue and yellow phosphors, and a mixture of the glue and infrared phosphors.
    Type: Application
    Filed: November 1, 2019
    Publication date: January 21, 2021
    Applicant: HANGZHOU HANHUI OPTOELECTRONIC TECHNOLOGY CO., LTD.
    Inventors: Xuke LI, Xiang PAN
  • Patent number: 10772303
    Abstract: The invention relates to eye-friendly green-blue mixed LED lighting methods and systems for chicken houses. In a chicken house, an evenly-distributed cyan light environment may be created for rearing broiler chickens. The chicken house may include mixed LED lamps associated with the cyan light environment, and the mixed LED lamp may be formed by combining green LED beads and blue LED beads on a lighting fixture with a mixing proportion of from about 0.2 to about 5. The mixed LED lamps may be used for about 24-hour lighting in the first three days of the breeding period. From the fourth day of the breeding period, the daily lighting duration may be progressively decreased by about one hour every day. The mixed LED lamps may be evenly arranged in the chicken house to form a square array.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: September 15, 2020
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Jinming Pan, Yefeng Yang, Xuke Li, Jinsong Jiang, Fengjia Dai
  • Patent number: 9828373
    Abstract: The invention provides compounds as CDK small-molecule inhibitors and uses thereof, the compounds can be used for treating inflammation and cell proliferation diseases. The novel compound of the invention is a powerful cyclin-dependent kinase 4 (CDK 4) or cyclin-dependent kinase-6 (CDK 6) inhibitor.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: November 28, 2017
    Assignee: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Bing Liu, Yingjun Zhang, Linlin Nie, Shun Bai, Mingyu Guan, Xuke Li, Changchung Cheng
  • Publication number: 20170121323
    Abstract: The invention provides compounds as CDK small-molecule inhibitors and uses thereof, the compounds can be used for treating inflammation and cell proliferation diseases. The novel compound of the invention is a powerful cyclin-dependent kinase 4 (CDK 4) or cyclin-dependent kinase-6 (CDK 6) inhibitor.
    Type: Application
    Filed: July 23, 2015
    Publication date: May 4, 2017
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Bing Liu, Yingjun ZHANG, Linlin NIE, Shun BAI, Mingyu GUAN, Xuke LI, Changchung CHENG
  • Patent number: 9578858
    Abstract: The present disclosure discloses a hybrid LED lighting method and system for chicken coops. For example, a closed or semi-open chicken coop is provided with the hybrid LED lightings including white LED beads and yellow LED beads in a mixing ratio of about 1:5 to about 5:1 in a regularly alternating manner. The average light intensity on the chicken cages' underside exposed to the light of the hybrid LED lighting is about 5 to about 30 Lux. The closed chicken coop is lit by a hybrid LED lighting every day during fattening period; the semi-open chicken coop is exposed to natural light in the daytime and lit by the hybrid LED lighting at night during fattening period. Implementation of the present disclosure improves growth of chickens, increases uniformity of chickens, and improves health and resistance to epidemic diseases.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: February 28, 2017
    Assignee: Hangzhou Langtuo Biotechnology Co., Ltd.
    Inventors: Xuke Li, Jinming Pan, Mingli Zhang, Jinsong Jiang, Fengjia Dai
  • Publication number: 20160270375
    Abstract: Implementations of the present disclosure relate to eye-friendly green-blue mixed LED lighting methods and systems for chicken houses. In a chicken house, an evenly-distributed cyan light environment may be created for rearing broiler chickens. The chicken house may include mixed LED lamps associated with the cyan light environment, and the mixed LED lamp may be formed by combining green LED beads and blue LED beads on a lighting fixture with a mixing proportion of from about 0.2 to about 5. The mixed LED lamps may be used for about 24-hour lighting in the first three days of the breading period. From the fourth day of the breading period, the daily lighting duration may be progressively decreased by about one hour every day. The mixed LED lamps may be evenly arranged in the chicken house to form a square array.
    Type: Application
    Filed: January 14, 2014
    Publication date: September 22, 2016
    Applicant: ZHEJIANG UNIVERSITY
    Inventors: Jinming Pan, Yefeng YANG, Xuke Li, Jinsong JIANG, Fengjia DAI
  • Publication number: 20160000046
    Abstract: The present disclosure discloses a hybrid LED lighting method and system for chicken coops. For example, a closed or semi-open chicken coop is provided with the hybrid LED lightings including white LED beads and yellow LED beads in a mixing ratio of about 1:5 to about 5:1 in a regularly alternating manner. The average light intensity on the chicken cages' underside exposed to the light of the hybrid LED lighting is about 5 to about 30 Lux. The closed chicken coop is lit by a hybrid LED lighting every day during fattening period; the semi-open chicken coop is exposed to natural light in the daytime and lit by the hybrid LED lighting at night during fattening period. Implementation of the present disclosure improves growth of chickens, increases uniformity of chickens, and improves health and resistance to epidemic diseases.
    Type: Application
    Filed: January 14, 2014
    Publication date: January 7, 2016
    Inventors: Xuke Li, Jinming PAN, Mingli ZHANG, Jinsong JIANG, Fengjia DAI
  • Patent number: 9119265
    Abstract: The invention discloses a ZIGBEE wireless network based plant tissue culture LED (light-emitting diode) light source control system, aiming to solve the problem that a plant tissue culture light source system cannot be monitored and treated with full time sections at present. The invention adopts the technical scheme that the wireless network based plant tissue culture LED light source control system comprises a master control end and a plurality of slave control ends.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: August 25, 2015
    Inventors: Xuedong Pan, Hong Zhou, Xuke Li, Wenhai Wang
  • Patent number: 8944631
    Abstract: This invention discloses a LED mixed lighting for tissue culture of orchids. Due to limitation of technology, currently it lacks of LED lighting directly used for orchids, especially for tissue culture of dendrobium candidum, ornamental dendrobium and phalaenopsis. This inventions adopts a technical proposal as follows: a LED fixed lighting for tissue culture of orchids is characterized in that said many red and blue LEDs will constitute several units; each unit has 3 blue LEDs and there are 8 red LEDs in elliptical or rounded patterns surrounding said 3 blue LEDs, and said 3 blue LEDs are gathered in triangular pattern, and said 8 red LEDs are separated at interval. This invention makes special arrangement of lamps and realizes adjustment of light quality and light period by turning on or turning off red LEDs and blue LEDs, and by this way, a LED mixed light which is distributed evenly and suitable for tissue culture of orchids.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: February 3, 2015
    Assignee: Hangzhou Hanhui Opto-Tech Co., Ltd.
    Inventors: Xuedong Pan, Hong Zhou, Xuke Li, Wenhai Wang, Huahong Huang
  • Patent number: 8742698
    Abstract: A Light Emitting Diode (LED) light source control system for intelligentized layer breeding, comprises a plurality of LED lamps (30) equipped at a layer breeding place and a LED light source controller (10). Each of the LED lamps (30) comprises a red light LED and a green light LED. The LED light source controller (10) controls the LED lamps (30) to emit green light during the brooding period and the improved period of a layer; and the LED light source controller (10) controls the LED lamps (30) to emit red light during the egg producing period of a layer. The LED light source controller (10) controls the illumination intensity of the LED lamps (30) by regulating the duty ratio of an output Pulse-Width Modulation (PWM). The LED light source controller (10) controls the illumination time of the LED lamps (30) by utilizing a clock unit so as to implement different illumination time respectively during various stages of the brooding period, the improved period and the egg producing period of a layer.
    Type: Grant
    Filed: December 31, 2010
    Date of Patent: June 3, 2014
    Assignee: Hangzhou Hanhui Optoelectronic Technology Co., Ltd.
    Inventors: Xuedong Pan, Xuke Li, Hong Zhou
  • Publication number: 20130271022
    Abstract: A Light Emitting Diode (LED) light source control system for intelligentized layer breeding, comprises a plurality of LED lamps (30) equipped at a layer breeding place and a LED light source controller (10). Each of the LED lamps (30) comprises a red light LED and a green light LED. The LED light source controller (10) controls the LED lamps (30) to emit green light during the brooding period and the improved period of a layer; and the LED light source controller (10) controls the LED lamps (30) to emit red light during the egg producing period of a layer. The LED light source controller (10) controls the illumination intensity of the LED lamps (30) by regulating the duty ratio of an output Pulse-Width Modulation (PWM). The LED light source controller (10) controls the illumination time of the LED lamps (30) by utilizing a clock unit so as to implement different illumination time respectively during various stages of the brooding period, the improved period and the egg producing period of a layer.
    Type: Application
    Filed: December 31, 2010
    Publication date: October 17, 2013
    Applicant: HANGZHOU HANHUI OPTOELECTRONIC TECHNOLOGY CO., LTD.
    Inventors: Xuedong Pan, Xuke Li, Hong Zhou
  • Publication number: 20120329397
    Abstract: The invention discloses a ZIGBEE wireless network based plant tissue culture LED (light-emitting diode) light source control system, aiming to solve the problem that a plant tissue culture light source system cannot be monitored and treated with full time sections at present. The invention adopts the technical scheme that the wireless network based plant tissue culture LED light source control system comprises a master control end and a plurality of slave control ends.
    Type: Application
    Filed: February 24, 2011
    Publication date: December 27, 2012
    Applicant: HANGZHOU HANHUI OPTO-TECH CO., LTD.
    Inventors: Xuedong Pan, Hong Zhou, Xuke Li, Wenhai Wang
  • Publication number: 20120293993
    Abstract: This invention discloses a LED mixed lighting for tissue culture of orchids. Due to limitation of technology, currently it lacks of LED lighting directly used for orchids, especially for tissue culture of dendrobium candidum, ornamental dendrobium and phalaenopsis. This inventions adopts a technical proposal as follows: a LED fixed lighting for tissue culture of orchids is characterized in that said many red and blue LEDs will constitute several units; each unit has 3 blue LEDs and there are 8 red LEDs in elliptical or rounded patterns surrounding said 3 blue LEDs, and said 3 blue LEDs are gathered in triangular pattern, and said 8 red LEDs are separated at interval. This invention makes special arrangement of lamps and realizes adjustment of light quality and light period by turning on or turning off red LEDs and blue LEDs, and by this way, a LED mixed light which is distributed evenly and suitable for tissue culture of orchids.
    Type: Application
    Filed: January 27, 2011
    Publication date: November 22, 2012
    Applicant: HANGZHOU HANHUI OPTO-TECH CO., LTD.
    Inventors: Xuedong Pan, Hong Zhou, Xuke Li, Wenhai Wang, Huahong Huang