Patents by Inventor XUKE ZHANG

XUKE ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Porcine pseudorabies virus, vaccine composition and preparation method and use thereof
    Patent number: 9650424
    Abstract: Provided in the embodiments of the present invention is a vaccine composition including an immune amount of attenuated live vaccine, inactivated vaccine, subunit vaccine, synthetic vaccine, or genetically engineered vaccine of the porcine pseudorabies virus strain. The vaccine composition can effectively induce antibody generation, and prevent infections of virulent strains of the porcine pseudorabies virus, and provides effective protection for pigs.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: May 16, 2017
    Assignee: PULIKE BIOLOGICAL ENGINEERING, INC.
    Inventors: Xuke Zhang, Jinzhong Sun, Rui Wu, Feifei Tan, Chaoyong Bai, Kegong Tian
  • Method of Attenuating Porcine Pseudorabies Virus, Attenuated Strains of Porcine Pseudorabies Virus, Vaccine Composition and Use Thereof
    Publication number: 20160317651
    Abstract: This invention provides a method of attenuating porcine pseudorabies virus, which can effectively and reproducibly attenuate porcine pseudorabies virus. The attenuated strain of porcine pseudorabies virus by use of said method can provide effective immunization for pigs.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 3, 2016
    Inventors: Kegong Tian, Feifei Tan, Jinzhong Sun, Xuke Zhang
  • Gene-Deleted Variant Strain Of Porcine Pseudorabies Virus, Vaccine Composition, Method Of Making The Same And Use Thereof
    Publication number: 20160317650
    Abstract: The present invention provides an attenuated strain of porcine pseudorabies virus (PRV), in which said attenuated strain of PRV is a variant strain of PRV with inactivation of gI/gE/11K/28K proteins. In addition, the present invention also provides a vaccine composition comprising the attenuated strain of PRV as an antigen, a preparation method and use thereof. Proved by immunogenicity and pathogenicity testing of the live vaccine, said live PRV vaccine can provide a good protection for pigs with no clinical signs observed, indicating excellent immune protection.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 3, 2016
    Inventors: Kegong TIAN, Xuke ZHANG, Jinzhong SUN, Feifei TAN
  • MACROLIDE COMPOUND
    Publication number: 20160304547
    Abstract: The present disclosure relates to a macrolide compound as shown by formula I and pharmaceutically acceptable salt thereof. The compound of the present disclosure is an antibacterial agent, and can be used to treat various bacterial and protozoal infections. The presnt disclosure further relates to the preparation method of the compound and a pharmaceutical composition thereof.
    Type: Application
    Filed: November 1, 2013
    Publication date: October 20, 2016
    Inventors: Xingjin Liu, Xuke Zhang
  • Gene-Deleted Variant Strain Of Porcine Pseudorabies Virus, Vaccine Composition, Method Of Making The Same And Use Thereof
    Publication number: 20160279232
    Abstract: The present invention provides an attenuated strain of porcine pseudorabies virus (PRV), in which said attenuated strain of PRV is a variant strain of PRV with inactivation of gI/gE/11K/28K proteins. In addition, the present invention also provides a vaccine composition comprising the attenuated strain of PRV as an antigen, a preparation method and use thereof. Proved by immunogenicity and pathogenicity testing of the live vaccine, said live PRV vaccine can provide a good protection for pigs with no clinical signs observed, indicating excellent immune protection.
    Type: Application
    Filed: February 26, 2016
    Publication date: September 29, 2016
    Inventors: Kegong TIAN, Xuke ZHANG, Jinzhong SUN, Feifei TAN
  • Gene-Deleted Variant Strain Of Porcine Pseudorabies Virus, Vaccine Composition, Method Of Making The Same And Use Thereof
    Publication number: 20160281065
    Abstract: The present invention provides an attenuated strain of porcine pseudorabies virus (PRV), in which said attenuated strain of PRV is a variant strain of PRV with inactivation of gI/gE/11K/28K proteins. In addition, the present invention also provides a vaccine composition comprising the attenuated strain of PRV as an antigen, a preparation method and use thereof. Proved by immunogenicity and pathogenicity testing of the live vaccine, said live PRV vaccine can provide a good protection for pigs with no clinical signs observed, indicating excellent immune protection.
    Type: Application
    Filed: January 6, 2015
    Publication date: September 29, 2016
    Inventors: Kegong TIAN, Xuke ZHANG, Jinzhong SUN, Feifei TAN
  • A Method of Attenuating Porcine Pseudorabies Virus, Attenuated Strains of Porcine Pseudorabies Virus, Vaccine Composition and Use Thereof
    Publication number: 20160279231
    Abstract: This invention provides a method of attenuating porcine pseudorabies virus, which can effectively and reproducibly attenuate porcine pseudorabies virus. The attenuated strain of porcine pseudorabies virus by use of said method can provide effective immunization for pigs.
    Type: Application
    Filed: July 6, 2015
    Publication date: September 29, 2016
    Inventors: Kegong Tian, Feifei Tan, Jinzhong Sun, Xuke Zhang
  • PORCINE PSEUDORABIES VIRUS, VACCINE COMPOSITION AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20160137700
    Abstract: Provided in embodiments of the present invention is a vaccine composition including an immune amount of attenuated live vaccine, inactivated vaccine, subunit vaccine, synthetic peptide vaccine, or genetically engineered vaccine of the porcine pseudorabies virus strain. The vaccine composition can effectively induce antibody generation, and prevent infections of virulent strains of the porcine pseudorabies virus, and provides effective protection for pigs.
    Type: Application
    Filed: April 30, 2014
    Publication date: May 19, 2016
    Applicant: PULIKE BIOLOGICAL ENGINEERING, INC.
    Inventors: Xuke ZHANG, Jinzhong Sun, Rui WU, Feifei TAN, Chaoyang BAI, Kegong TIAN
  • PORCINE PSEUDORABIES VIRUS, VACCINE COMPOSITION AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20160114029
    Abstract: Provided in the embodiments of the present invention is a vaccine composition including an immune amount of attenuated live vaccine, inactivated vaccine, subunit vaccine, synthetic vaccine, or genetically engineered vaccine of the porcine pseudorabies virus strain. The vaccine composition can effectively induce antibody generation, and prevent infections of virulent strains of the porcine pseudorabies virus, and provides effective protection for pigs.
    Type: Application
    Filed: December 28, 2015
    Publication date: April 28, 2016
    Applicant: PULIKE BIOLOGICAL ENGINEERING, INC.
    Inventors: XUKE ZHANG, JINZHONG SUN, RUI WU, FEIFEI TAN, CHAOYONG BAI, KEGONG TIAN