Patents by Inventor Xun Wang

Xun Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020146839
    Abstract: A method of injecting, isolating and separating mixed analytes from one or more samples. The method includes collecting successive fractions from each of a plurality of samples at discrete points in time. Fractions may be analyzed at the time of collecting, or later, using one or more detector systems. In one embodiment, a processor controls the elutions of fractions by modulating the migration field in a separation pathway. The processor also controls distribution of the fraction into a particular collection well of a plurality of collection wells.
    Type: Application
    Filed: January 28, 2002
    Publication date: October 10, 2002
    Inventors: Andras Guttman, Liang Shi, Xun Wang
  • Publication number: 20020142324
    Abstract: A method for gene identification using genome-wide deletion of genes is provided. The method may be used with any organism capable of homologous recombination, including plants, plant pathogens, microorganisms, and vertebrates. Also provided are genes isolated from Cochliobolus that code for polypeptides essential for normal fungal growth and development and/or for pathogenicity, and methods to identify polypeptides essential to the viability of an organism and/or those associated with pathogenicity. The invention also includes methods of using these polypeptides to identify fungicides. The invention can further be used in a screening assay to identify inhibitors that are potential fungicides.
    Type: Application
    Filed: September 24, 2001
    Publication date: October 3, 2002
    Inventors: Xun Wang, Barbara Gillian Turgeon, Olen Yoder, Jianguo Wu
  • Publication number: 20020034753
    Abstract: Currently, three technologies are utilized for analysis of gene expression: hybridization-based technologies, PCR-based technologies, and sequence-based technologies. The present invention provides a method for analyzing the presence and/or amount of a specific nucleic acid using a solid support and a capture probe complementary to a region of a target nucleic acid, and polymerizing a labeled extension complementary to the target nucleic acid. The invention provides a method of analysis of all types of nucleic acids, and can be used to study multiple genes in a single assay using different capture probes conjugated to different class of microspheres that can be mixed in any desired combination.
    Type: Application
    Filed: May 14, 2001
    Publication date: March 21, 2002
    Inventors: Li Yang, Xun Wang, Tong Zhu, Liang Shi
  • Patent number: 6291224
    Abstract: This invention relates to newly identified polynucleotides and polypeptides, variants and derivatives of same; methods for making the polynucleotides, polypeptides, variants, derivatives and antagonists. In particular the invention relates to polynucleotides and polypeptides of the phytate metabolic pathway.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: September 18, 2001
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Susan J. Martino-Catt, Hongyu Wang, Larry R. Beach, Xun Wang, Benjamin A. Bowen
  • Patent number: 6239330
    Abstract: Methods for identifying organisms capable of degrading fumonisin. Fumonisin can be incorporated into culture medium for selection of organisms resistant to fumonisin and/or capable of growing on fumonisin as a sole carbon source. Using this method, several organisms have been identified. These organisms can be used to isolate the enzymes and the genes responsible for conferring fumonisin-resistance. The gene can be cloned and inserted into a suitable expression vector so that the protein can be further characterized. Additionally, the DNA encoding for fumonisin degrading enzymes can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: May 29, 2001
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Jonathan Duvick, Joyce R. Maddox, Xun Wang
  • Patent number: 6229071
    Abstract: Methods for identifying organisms capable of degrading fumonisin. Fumonisin can be incorporated into culture medium for selection of organisms resistant to fumonisin and/or capable of growing on fumonisin as a sole carbon source. Using this method, several organisms have been identified. These organisms can be used to isolate the enzymes and the genes responsible for conferring fumonisin-resistance. The gene can be cloned and inserted into a suitable expression vector so that the protein can be further characterized. Additionally, the DNA encoding for fumonisin degrading enzymes can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: May 8, 2001
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Jonathan Duvick, Joyce R. Maddox, Tracy A. Rood, Xun Wang
  • Patent number: 6197561
    Abstract: This invention relates to newly identified polynucleotides and polypeptides, variants and derivatives of same; methods for making the polynucleotides, polypeptides, variants, derivatives and antagonists. In particular the invention relates to polynucleotides and polypeptides of the phytate metabolic pathway.
    Type: Grant
    Filed: July 17, 1998
    Date of Patent: March 6, 2001
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Susan J. Martino-Catt, Hongyu Wang, Larry R. Beach, Xun Wang, Benjamin A. Bowen
  • Patent number: 6025188
    Abstract: Methods for identifying organisms capable of degrading fumonisin. Fumonisin can be incorporated into culture medium for selection of organisms resistant to fumonisin and/or capable of growing on fumonisin as a sole carbon source. Using this method, several organisms have been identified. These organisms can be used to isolate the enzymes and the genes responsible for conferring fumonisin-resistance. The gene can be cloned and inserted into a suitable expression vector so that the protein can be further characterized. Additionally, the DNA encoding for fumonisin degrading enzymes can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: February 15, 2000
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Jonathan Duvick, Joyce R. Maddox, Tracy A. Rood, Xun Wang, Benjamin A. Bowen, Jacob T. Gilliam
  • Patent number: 5853991
    Abstract: A process is described in which PCR-based cDNA libraries with anchored ends are made, a PCR-based cDNA subtracted (PCSUB) library is produced therefrom, and the ends of a cDNA clone are isolated, via PCR, from an anchored-ends library.
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: December 29, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Xun Wang, Jonathan P. Duvick, Steven P. Briggs
  • Patent number: 5837468
    Abstract: A process is described in which PCR-based cDNA libraries with anchored ends are made, a PCR-based cDNA subtracted (PCSUB) library is produced therefrom, and the ends of a cDNA clone are isolated, via PCR, from an anchored-ends library.
    Type: Grant
    Filed: May 19, 1997
    Date of Patent: November 17, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Xun Wang, Jonathan P. Duvick, Steven P. Briggs
  • Patent number: 5792931
    Abstract: Methods for identifying organisms capable of degrading fumonisin. Fumonisin can be incorporated into culture medium for selection of organisms resistant to fumonisin and/or capable of growing on flumonisin as a sole carbon source. Using this method, several organisms have been identified. These organisms can be used to isolate the enzyme and the gene responsible for conferring fumonisin-resistance. The gene can be cloned and inserted into a suitable expression vector so that the protein can be further characterized. Additionally, the DNA encoding for furaonisin-resistance can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes. Methods for detoxification in grain processing and in animal feed and rumen microbes are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 11, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Jonathan Duvick, Tracy Rood, Joyce R. Maddox, Xun Wang
  • Patent number: 5716820
    Abstract: Methods for identifying organisms capable of degrading fumonisin. Fumonisin can be incorporated into culture medium for selection of organisms resistant to fumonisin. Using this method, several organisms have been identified. These organisms can be used to isolate the enzyme and the gene responsible for conferring fumonisin-resistance. The gene can be cloned and inserted into a suitable expression vector so that the protein can be further characterized. Additionally, the DNA encoding for fumonisin-resistance can be used to transform plant cells normally susceptible to Fusarium infection. Plants can be regenerated from the transformed plant cells. In this way, a transgenic plant can be produced with the capability of degrading fumonisin.
    Type: Grant
    Filed: February 26, 1997
    Date of Patent: February 10, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Jon Duvick, Tracy Rood, Xun Wang