Patents by Inventor Xunrong Luo

Xunrong Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to detect autoantibody reactivity for deamidated insulin autoantigen in diabetes
    Patent number: 10570185
    Abstract: Provided herein are epitopes and mimotopes thereof useful in the diagnosis and treatment of type 1 diabetes (T1D), as well as antibodies recognizing such epitopes, and diagnostics, therapeutics, kits, and methods of use thereof.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: February 25, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Jing Jin, Xunrong Luo, Grazia Aleppo
  • Scaffold Delivery of Immune Suppressors and Transplant Material for Control of Transplant Rejection
    Publication number: 20190275082
    Abstract: The present invention provides compositions, devices, and methods for the coordinated delivery of transplant material and immune suppressors for control of transplant rejection. In particular embodiments, immune suppression cells (e.g., regulatory T cells) and transplant material (e.g., cells, tissue, etc.) are provided within a delivery scaffold for transplant into a subject.
    Type: Application
    Filed: November 1, 2018
    Publication date: September 12, 2019
    Inventors: Xunrong Luo, Lonnie Shea, John G. Graham, Kathryn L. Pothoven, Xiaomin Zhang
  • ANTIOXIDANT SCAFFOLDS FOR BETA CELL DELIVERY
    Publication number: 20180085492
    Abstract: Provided herein are thermoresponsive citrate-based hydrogels and methods of use thereof for cell delivery. In particular, pancreatic islet cells entrapped within poly(polyethyleneglycol citrate-co-N isopropylacrylamide) (PPCN) hydrogels are provided herein, as well as methods of use thereof for extra-hepatic islet transplantation.
    Type: Application
    Filed: September 29, 2017
    Publication date: March 29, 2018
    Inventors: Guillermo A. Ameer, Xunrong Luo, Xiaomin Zhang, Yunxiao Zhu
  • Scaffold Delivery of Immune Suppressors and Transplant Material for Control of Transplant Rejection
    Publication number: 20170281680
    Abstract: The present invention provides compositions, devices, and methods for the coordinated delivery of transplant material and immune suppressors for control of transplant rejection. In particular embodiments, immune suppression cells (e.g., regulatory T cells) and transplant material (e.g., cells, tissue, etc.) are provided within a delivery scaffold for transplant into a subject.
    Type: Application
    Filed: November 14, 2016
    Publication date: October 5, 2017
    Inventors: Xunrong Luo, Lonnie Shea, John G. Graham, Kathryn L. Pothoven, Xiaomin Zhang
  • METHOD TO DETECT AUTOANTIBODY REACTIVITY FOR DEAMIDATED INSULIN AUTOANTIGEN IN DIABETES
    Publication number: 20160355564
    Abstract: Provided herein are epitopes and mimotopes thereof useful in the diagnosis and treatment of type 1 diabetes (T1D), as well as antibodies recognizing such epitopes, and diagnostics, therapeutics, kits, and methods of use thereof.
    Type: Application
    Filed: May 11, 2016
    Publication date: December 8, 2016
    Inventors: Jing Jin, Xunrong Luo, Grazia Aleppo
  • Use of ECDI-fixed cell tolerance as a method for preventing allograft rejection
    Patent number: 8734786
    Abstract: The present invention provides methods, systems, and compositions for inducing donor-specific tolerance. In particular, the present invention provides methods of administering ECDI-treated cells before, during, and/or after administration of donor transplant cells or a donor allograft in order to induce tolerance for the cells and/or allograft in a recipient.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: May 27, 2014
    Assignee: Northwestern University
    Inventors: Stephen D. Miller, Xunrong Luo
  • Scaffold Delivery of Immune Suppressors and Transplant Material for Control of Transplant Rejection
    Publication number: 20140120152
    Abstract: The present invention provides compositions, devices, and methods for the coordinated delivery of transplant material and immune suppressors for control of transplant rejection. In particular embodiments, immune suppression cells (e.g., regulatory T cells) and transplant material (e.g., cells, tissue, etc.) are provided within a delivery scaffold for transplant into a subject.
    Type: Application
    Filed: October 31, 2013
    Publication date: May 1, 2014
    Applicant: Northwestern University
    Inventors: Xunrong Luo, Lonnie Shea, John G. Graham, Kathryn L. Pothoven, Xiaomin Zhang
  • USE OF ECDI-FIXED CELL TOLERANCE AS A METHOD FOR PREVENTING ALLOGRAFT REJECTION
    Publication number: 20110064709
    Abstract: The present invention provides methods, systems, and compositions for inducing donor-specific tolerance. In particular, the present invention provides methods of administering ECDI-treated cells before, during, and/or after administration of donor transplant cells or a donor allograft in order to induce tolerance for the cells and/or allograft in a recipient.
    Type: Application
    Filed: September 16, 2010
    Publication date: March 17, 2011
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Stephen D. Miller, Xunrong Luo