Patents by Inventor Xuyen Dai Hoa

Xuyen Dai Hoa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A Microfluidic Device for Culturing Cells Comprising A Biowall, A Bead Bed and A Biointerface and Methods of Modelling Said Biointerface Thereof
    Publication number: 20200377838
    Abstract: A technique for producing an artificial biointerface involves providing a patterned microfluidic chip having: a chamber divided by a fluid-permeable fencing into a central region and two flanking channels; and at least 3 fluid paths, each of the paths extending across one of the central region and the two flanking channels. A porous packing of rigid beads is placed within the central region to define a bead bed, the beads being of a size to be retained by the fencing. A biowall can be grown on at least one segment of the fencing separating the central region from one flanking channel, the biowall formed at least in part by live cells cultured on the beads. Beads may be modified, coated or functionalized to improve cell attachment and growth, and for reporting, or dosing particles or molecules can be conveniently added to the bead bed.
    Type: Application
    Filed: February 18, 2019
    Publication date: December 3, 2020
    Applicant: National Research Council of Canada
    Inventors: Teodor VERES, Xuyen Dai HOA, Jamal DAOUD, Caroline MIVILLE-GODIN, Lidija MALIC
  • Pattenred film for forming fluid-filled blister, microfluidic blister, and kit and method of forming
    Patent number: 10046893
    Abstract: A patterned thermoplastic elastomer (TPE) film for fabricating a liquid-filled blister, has a blister-sized cavity in fluid communication with a microfluidic channel via a gating region.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: August 14, 2018
    Assignee: National Research Council of Canada
    Inventors: Mojra Janta, Xuyen Dai Hoa, Matthias Geissler, Teodor Veres
  • PATTENRED FILM FOR FORMING FLUID-FILLED BLISTER, MICROFLUIDIC BLISTER, AND KIT AND METHOD OF FORMING
    Publication number: 20170291747
    Abstract: A patterned thermoplastic elastomer (TPE) film for fabricating a liquid-filled blister, has a blister-sized cavity in fluid communication with a microfluidic channel via a gating region.
    Type: Application
    Filed: April 11, 2017
    Publication date: October 12, 2017
    Applicant: NATIONAL RESEARCH COUNCIL OF CANADA
    Inventors: Mojra JANTA, Xuyen Dai HOA, Matthias GEISSLER, Teodor VERES
  • Centrifugally-enhanced capture method and device
    Patent number: 9442108
    Abstract: In a centrifugal microfluidic device for conducting capture assays, a microfluidic platform rotates in a plane of rotation and has at least one capture surface for immobilizing a target particle of interest in the device. The capture surface oriented so that it is not parallel to the plane of rotation of the device and is positionally fixed in the device during operation of the device. The centrifugal force arising from rotation of the device forces the target particles against the capture surface. Capture efficiency is independent of the rate of flow of the fluid and independent of the rate of rotation of the microfluidic platform.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: September 13, 2016
    Assignee: National Research Council of Canada
    Inventors: Liviu Clime, Xuyen Dai Hoa, Teodor Veres, Francois Normandin
  • CENTRIFUGALLY-ENHANCED CAPTURE METHOD AND DEVICE
    Publication number: 20140212992
    Abstract: In a centrifugal microfluidic device for conducting capture assays, a microfluidic platform rotates in a plane of rotation and has at least one capture surface for immobilizing a target particle of interest in the device. The capture surface oriented so that it is not parallel to the plane of rotation of the device and is positionally fixed in the device during operation of the device. The centrifugal force arising from rotation of the device forces the target particles against the capture surface. Capture efficiency is independent of the rate of flow of the fluid and independent of the rate of rotation of the microfluidic platform.
    Type: Application
    Filed: August 27, 2012
    Publication date: July 31, 2014
    Applicant: NATIONAL RESEARCH COUNCIL OF CANADA
    Inventors: Liviu Clime, Xuyen Dai Hoa, Teodor Veres, Francois Normandin