Patents by Inventor Xuyuan Gu

Xuyuan Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligomer-phenothiazine conjugates
    Patent number: 10869933
    Abstract: The invention relates to (among other things) oligomer-phenothiazine conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated phenothiazine compounds.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: December 22, 2020
    Assignee: Nektar Therapeutics
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier
  • Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine
    Patent number: 10844076
    Abstract: The instant disclosure relates to (among other things) compounds that are derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine. The compounds provided possess unique effects and differences over other phenyltriazines known in the art.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: November 24, 2020
    Assignee: Nektar therapeutics
    Inventors: Pankaj Sharma, Vijay Kumar Khatri, Xuyuan Gu, Yuan Song, Michael Lixin Shen, Jennifer Riggs-Sauthier, Neel K. Anand, Antoni Kozlowski, Aleksandrs Odinecs, Timothy A. Riley, Zhongxu Ren, YongQi Mu, Xiaoming Shen, Xuejun Yuan, Natalia Aurrecoechea, Donogh John Roger O'Mahony, Bo-Liang Deng
  • OLIGOMER-PHENOTHIAZINE CONJUGATES
    Publication number: 20200038517
    Abstract: The invention relates to (among other things) oligomer-phenothiazine conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated phenothiazine compounds.
    Type: Application
    Filed: October 11, 2019
    Publication date: February 6, 2020
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier
  • Oligomer-phenothiazine conjugates
    Patent number: 10485877
    Abstract: The invention relates to (among other things) oligomer-phenothiazine conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated phenothiazine compounds.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: November 26, 2019
    Assignee: Nektar Therapeutics
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier
  • DERIVATIVES OF 6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZIN-5-AMINE
    Publication number: 20190071454
    Abstract: The instant disclosure relates to (among other things) compounds that are derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine. The compounds provided possess unique effects and differences over other phenyltriazines known in the art.
    Type: Application
    Filed: November 6, 2018
    Publication date: March 7, 2019
    Inventors: Pankaj Sharma, Vijay Kumar Khatri, Xuyuan Gu, Yuan Song, Michael Lixin Shen, Jennifer Riggs-Sauthier, Neel K. Anand, Antoni Kozlowski, Aleksandrs Odinecs, Timothy A. Riley, Zhongxu Ren, YongQi Mu, Xiaoming Shen, Xuejun Yuan, Natalia Aurrecoechea, Donogh John Roger O'Mahony, Bo-Liang Deng
  • Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine
    Patent number: 10189859
    Abstract: The instant disclosure relates to (among other things) compounds that are derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine. The compounds provided possess unique effects and differences over other phenyltriazines known in the art.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: January 29, 2019
    Assignee: Nektar Therapeutics
    Inventors: Pankaj Sharma, Vijay Kumar Khatri, Xuyuan Gu, Yuan Song, Michael Lixin Shen, Jennifer Riggs-Sauthier, Neel K. Anand, Antoni Kozlowski, Aleksandrs Odinecs, Timothy A. Riley, Zhongxu Ren, YongQi Mu, Xiaoming Shen, Xuejun Yuan, Natalia Aurrecoechea, Donogh John Roger O'Mahony, Bo-Liang Deng
  • OLIGOMER-PHENOTHIAZINE CONJUGATES
    Publication number: 20180243429
    Abstract: The invention relates to (among other things) oligomer-phenothiazine conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated phenothiazine compounds.
    Type: Application
    Filed: May 1, 2018
    Publication date: August 30, 2018
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier
  • Oligomer-tricyclic conjugates
    Patent number: 9725431
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water-soluble oligomer.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: August 8, 2017
    Assignee: Nektar Therapeutics
    Inventors: Wen Zhang, Xuyuan Gu, Stephanie Allums-Donald, Jennifer Riggs-Sauthier
  • DERIVATIVES OF 6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZIN-5-AMINE
    Publication number: 20170066782
    Abstract: The instant disclosure relates to (among other things) compounds that are derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine. The compounds provided possess unique effects and differences over other phenyltriazines known in the art.
    Type: Application
    Filed: December 19, 2014
    Publication date: March 9, 2017
    Inventors: Pankaj Sharma, Vijay Kumar Khatri, Xuyuan Gu, Yuan Song, Michael Lixin Shen, Jennifer Riggs-Sauthier, Neel K. Anand, Antoni Kozlowski, Aleksandrs Odinecs, Timothy A. Riley, Zhongxu Ren, YongQi Mu, Xiaoming Shen, Xuejun Yuan, Natalia Aurrecoechea, Donogh John Roger O'Mahony
  • Oligomer-amino acid conjugates
    Patent number: 9487473
    Abstract: The invention relates to (among other things) oligomer-amino acid conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated amino acid compounds.
    Type: Grant
    Filed: October 22, 2015
    Date of Patent: November 8, 2016
    Assignee: Nektar Therapeutics
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier
  • OLIGOMER-AMINO ACID CONJUGATES
    Publication number: 20160096799
    Abstract: The invention relates to (among other things) oligomer-amino acid conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated amino acid compounds.
    Type: Application
    Filed: October 22, 2015
    Publication date: April 7, 2016
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier
  • Oligomer-amino acid conjugates
    Patent number: 9192681
    Abstract: The invention relates to (among other things) oligomer-amino acid conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated amino acid compounds.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: November 24, 2015
    Assignee: NEKTAR THERAPEUTICS
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier
  • Oligomer-protease inhibitor conjugates
    Patent number: 9107956
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the small molecule drug not attached to the water-soluble oligomer.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: August 18, 2015
    Assignee: NEKTAR THERAPEUTICS
    Inventors: Jennifer Riggs-Sauthier, Lin Cheng, Tacey X. Viegas, Xuyuan Gu, Franco J. Duarte, Wen Zhang
  • Water-Soluble Polymer Conjugates of Topotecan
    Publication number: 20140371258
    Abstract: Provided herein are water-soluble polymer conjugates of topotecan, along with compositions comprising the conjugates and related methods of making and using the same.
    Type: Application
    Filed: December 16, 2011
    Publication date: December 18, 2014
    Applicant: Nektar Therapeutics
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier, Michael D. Bentley, Tacey X. Viegas
  • OLIGOMER-TRICYCLIC CONJUGATES
    Publication number: 20140100268
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water-soluble oligomer.
    Type: Application
    Filed: September 6, 2013
    Publication date: April 10, 2014
    Applicant: NEKTAR THERAPEUTICS
    Inventors: Wen Zhang, Xuyuan Gu, Stephanie Allums-Donald, Jennifer Riggs-Sauthier
  • OLIGOMER-PROTEASE INHIBITOR CONJUGATES
    Publication number: 20140045770
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the small molecule drug not attached to the water-soluble oligomer.
    Type: Application
    Filed: October 16, 2013
    Publication date: February 13, 2014
    Applicant: NEKTAR THERAPEUTICS
    Inventors: Jennifer RIGGS-SAUTHIER, Lin Cheng, Tacey X. Viegas, Xuyuan Gu, Franco J. Duarte, Wen Zhang
  • Oligomer-protease inhibitor conjugates
    Patent number: 8598364
    Abstract: The invention provides protease inhibitors that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the protease inhibitors not attached to the water-soluble oligomer.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: December 3, 2013
    Assignee: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Lin Cheng, Tacey X. Viegas, Xuyuan Gu, Franco J. Duarte, Wen Zhang
  • Oligomer-tricyclic conjugates
    Patent number: 8569380
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer.
    Type: Grant
    Filed: November 28, 2008
    Date of Patent: October 29, 2013
    Assignee: Nektar Therapeutics
    Inventors: Wen Zhang, Xuyuan Gu, Stephanie Allums, Jennifer Riggs-Sauthier
  • Oligomer-Amino Acid Conjugates
    Publication number: 20120053237
    Abstract: The invention relates to (among other things) oligomer-amino acid conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated amino acid compounds.
    Type: Application
    Filed: February 24, 2010
    Publication date: March 1, 2012
    Applicant: NEKTAR THERAPEUTICS
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier
  • Oligomer-Phenothiazine Conjugates
    Publication number: 20120046279
    Abstract: The invention relates to (among other things) oligomer-phenothiazine conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated phenothiazine compounds.
    Type: Application
    Filed: January 28, 2010
    Publication date: February 23, 2012
    Applicant: Nektar Therapeutics
    Inventors: Xuyuan Gu, Jennifer Riggs-Sauthier