Abstract: Disclosed is an adjustable arm device for cable training. The adjustable arm device has a mounting base fitted on a vertical frame, a locking component for locking the mounting base, a swing arm having a guide pulley at its connecting end for the training cable to slide against, a swivel pulley housing at the extending end of the swing arm, a vertically adjustable joint at the connecting end of the swing arm including a horizontal support shaft, a vertical positioning seat, a vertical angle locking component that allows vertical swinging, a horizontal adjustable joint on the mounting base below the vertical joint, including a vertical support shaft, a horizontal positioning seat, a horizontal angle locking component that allows horizontal swinging, and a cable passage between the connecting end of the swing arm and the swivel pulley housing for passage of the training cable.

Abstract: Disclosed is an adjustable arm device for cable training. The adjustable arm device has a mounting base fitted on a vertical frame, a locking component for locking the mounting base, a swing arm having a guide pulley at its connecting end for the training cable to slide against, a swivel pulley housing at the extending end of the swing arm, a vertically adjustable joint at the connecting end of the swing arm including a horizontal support shaft, a vertical positioning seat, a vertical angle locking component that allows vertical swinging, a horizontal adjustable joint on the mounting base below the vertical joint, including a vertical support shaft, a horizontal positioning seat, a horizontal angle locking component that allows horizontal swinging, and a cable passage between the connecting end of the swing arm and the swivel pulley housing for passage of the training cable.

Abstract: A terrain-adaptive weight training sled with free steering including: a main frame with first and second ends remote from each other; a resistance wheel rotatably disposed on the first end and having a damping structure; two rotatable and freely steerable omni-wheels disposed on both sides of the second end; and a pulling member having a connecting end, a user-operated end, and a flexible extension section, the connecting end being used to connect with the second end of the main frame and the user-operated end being used for the user to apply force for pulling. The height of the first end is lower than the second end, relatively causing the second end to have an upward inclination angle ? which is between 6° and 15°. When the user pulls the second end to turn by the pulling member, the two omni-wheels are driven to produce a turning motion thereafter.

Abstract: The present disclosure relates to treating cancer patients with anti-dendritic cells (anti-DCs)/anti-immunogenic cell death (anti-ICD) bispecific engager combined with tumor ICD inducers to enhance the dendritic cell activity. Exemplary polyvalent proteins include at least one DC binding site and at least one ICD binding site. In certain embodiments, the binding sites may be linked through a constant immunoglobulin region. Anti-DC and anti-ICD monoclonal antibodies are also provided.

Abstract: The present invention provides a multi-stage amplifier including at least one inter-stage amplifier, an output amplifier, a high-pass filter and a feedback amplifier is disclosed. The at least one inter-stage amplifier is configured to amplify an input signal to generate a signal. The output amplifier is configured to receive the signal to generate an output signal. The high-pass filter is configured to filter the signal and the output signal to generate a filtered signal and a filtered output signal, respectively. The feedback amplifier is configured to receive the filtered signal and the filtered output signal to generate a feedback signal to an input terminal of one of the at least one inter-stage amplifier and the output amplifier.

Abstract: A weight training sled with enhanced load effect is disclosed. The main frame has a first end and a second end remote from each other. Two first wheels, in a rotatable state, disposed at either side of the first end. A second wheel, in a rotatable state, disposed at the second end. The damping structure, disposed on the main frame and connected to the second wheel. An operating handle, erected at the first end of the main frame. An auxiliary push frame, erected at the second end of the main frame with a stand portion and a handlebar portion coupled to the upper end of the stand portion. An enhanced weight load holder, disposed on the handlebar portion, including a stop portion spaced from the handlebar portion, forming a handgrip clearance space. A weight member, placed on the enhanced weight load holder and limited in position by the stop portion.

Abstract: A weight training sled with enhanced load effect is disclosed. The main frame has a first end and a second end remote from each other. Two first wheels, in a rotatable state, disposed at either side of the first end. A second wheel, in a rotatable state, disposed at the second end. The damping structure, disposed on the main frame and connected to the second wheel. An operating handle, erected at the first end of the main frame. An auxiliary push frame, erected at the second end of the main frame with a stand portion and a handlebar portion coupled to the upper end of the stand portion. An enhanced weight load holder, disposed on the handlebar portion, including a stop portion spaced from the handlebar portion, forming a handgrip clearance space. A weight member, placed on the enhanced weight load holder and limited in position by the stop portion.

Abstract: A terrain-adaptive weight training sled with free steering, having a main frame with a first end and a second end remote from each other, a push frame erected on the first end, a resistance wheel rotatable disposed on the first end and assembled with a damping structure for retarding the resistance wheel, two omni-wheels, in a rotatable and freely steerable state, disposed on both sides of the second end, and a pulling member having a connecting end, a user-operated end, and a flexible extension section, wherein the connecting end being used to connect with the second end of the main frame and the user-operated end being used for the user to apply force for pulling, whereby when the user pulls the second end to turn by means of the pulling member, the two omni-wheels are driven to produce a turning motion thereafter.

Abstract: A weight training sled with enhanced component force effect is disclosed, the sled including: a main frame with first and second ends remote from each other; a push frame, erected at the first end of the main frame; an operating handle, erected at the second end; a resistance wheel, in a rotatable state, disposed at the first end and equipped with a damping structure for providing a damping effect to retard the rolling of the resistance wheel; two wheels, in a rotatable state, disposed at either side of the second end, allowing the main frame to be displaced by utilizing the rolling of each of the wheels and the resistance wheel; and wherein, the height of the first end of the main frame is lower than the height of the second end, relatively causing the second end to have an upward inclination angle ? which is between 3° and 30°.

Abstract: The present invention provides a multi-stage amplifier, wherein the multi-stage amplifier includes a plurality of amplifier stages and a compensation circuit. The compensation circuit is coupled to an output terminal of one of the plurality of amplifier stages, and the compensation circuit includes a first auxiliary amplifier, a capacitor, a second auxiliary amplifier, a first resistor and a second resistor. The capacitor is coupled between an input terminal and an output terminal of the first auxiliary amplifier. The second auxiliary amplifier is coupled to the first auxiliary amplifier. The first resistor is coupled between an input terminal and an output terminal of the second auxiliary amplifier. The second resistor is coupled between an output terminal of the first auxiliary amplifier and a ground voltage.

Abstract: A rope pull training device is disclosed, which includes a mainframe having a vertical post, two laterally opposite hauling ropes respectively configured on the mainframe, a resisting unit connected to the mainframe to provide a resisting force against the pulling force applied on the hauling ropes, and a guiding structure fitted on the vertical post, capable of sliding up and down along the vertical post. Each of the hauling ropes is respectively connected to the guiding structure, and each of the hauling ropes respectively goes through the guiding structure. One end of the hauling rope close to the guiding structure is connected with a handle. The hauling ropes are in a cyclic form. The hauling ropes can maintain a tightened state, and can be applied in different exercising modes.

Abstract: Disclosed is a weight training device that can be transformed into a hand truck. The device includes a main frame, two first wheels, a second wheel, two first installing tubes, two second installing tubes and two operating parts, wherein the main frame is used for loading at least one heavy object. Each wheel is fitted on the main frame in a rotational manner, so that the main frame can be moved through the rolling of the wheels. Each of the first installing tubes are opposite each other and respectively extends upward. Each of the second installing tubes are opposite each other and respectively extend away from the main frame. Each of the operating parts are opposite each other in the lateral direction and are respectively and selectively configured on each of the first or each of the second installing tubes, so as to shift the operating mode of weight training.

Abstract: A rope pull training device is disclosed, which includes a mainframe having a vertical post, two laterally opposite hauling ropes respectively configured on the mainframe, a resisting unit connected to the mainframe to provide a resisting force against the pulling force applied on the hauling ropes, and a guiding structure fitted on the vertical post, capable of sliding up and down along the vertical post. Each of the hauling ropes is respectively connected to the guiding structure, and each of the hauling ropes respectively goes through the guiding structure. One end of the hauling rope close to the guiding structure is connected with a handle. The hauling ropes are in a cyclic form. The hauling ropes can maintain a tightened state, and can be applied in different exercising modes.

Abstract: A method is provided for determining the efficacy of GPC3-targeting drug therapy for cancer in a patient before the start of GPC3-targeting drug therapy or for determining the continuation of GPC3-targeting drug therapy for a patient treated with GPC3-targeting therapy. The method includes determining the number of an immunocyte or an expression level of a molecule expressed on the immunocyte in a biological sample isolated from the patient before the start of GPC3-targeting drug therapy and/or the patient treated with the GPC3-targeting drug therapy, wherein when the number of the immunocyte or the expression level of the molecule expressed on the immunocyte is a predetermined value, the efficacy of the GPC3-targeting drug therapy is determined or the continuation of the GPC3-targeting drug therapy is determined. GPC3-targeting drugs and drug preparations for use according to the disclosed methods are also provided.

Abstract: Disclosed is a weight training device that can be transformed into a hand truck. The device includes a main frame, two first wheels, a second wheel, two first installing tubes, two second installing tubes and two operating parts, wherein the main frame is used for loading at least one heavy object. Each wheel is fitted on the main frame in a rotational manner, so that the main frame can be moved through the rolling of the wheels. Each of the first installing tubes are opposite each other and respectively extends upward. Each of the second installing tubes are opposite each other and respectively extend away from the main frame. Each of the operating parts are opposite each other in the lateral direction and are respectively and selectively configured on each of the first or each of the second installing tubes, so as to shift the operating mode of weight training.

Abstract: A flywheel exerciser having a hybrid resistance system includes: a body having a flywheel unit; a wind resistance system disposed on the flywheel unit; and a magnetic resistance system disposed on the flywheel unit. The wind resistance system is a conventional wind resistance which provides segmental adjustment, the present invention is additionally provided with a magnetic resistance system. When the resistance generated by the wind resistance system is insufficient or excessive, the resistance can be further finely increased or decreased by adjusting the magnetic resistance system to provide the resistance that best meets the user's needs.

Abstract: An interactive sports management device combined with human physiological information and sports information includes a user module, an exercise module and a management module, wherein the user module is used to detect the physiological information of the user, and transmit the user identifier and the physiological information to the exerciser module. The exercise module is used to collect the sports information of the sports fitness equipment, and transmit the user identifier, the physiological information, the exerciser identifier and the sports information to the management module. The management module transmits the management information to the exerciser module. In this way, the sports information generated when the specific person uses the specific sports fitness equipment for exercise is combined with the human physiological information into the personalized information.