Abstract: Disclosed is a weight training device that can be transformed into a hand truck. The device includes a main frame, two first wheels, a second wheel, two first installing tubes, two second installing tubes and two operating parts, wherein the main frame is used for loading at least one heavy object. Each wheel is fitted on the main frame in a rotational manner, so that the main frame can be moved through the rolling of the wheels. Each of the first installing tubes are opposite each other and respectively extends upward. Each of the second installing tubes are opposite each other and respectively extend away from the main frame. Each of the operating parts are opposite each other in the lateral direction and are respectively and selectively configured on each of the first or each of the second installing tubes, so as to shift the operating mode of weight training.

Abstract: A rope pull training device is disclosed, which includes a mainframe having a vertical post, two laterally opposite hauling ropes respectively configured on the mainframe, a resisting unit connected to the mainframe to provide a resisting force against the pulling force applied on the hauling ropes, and a guiding structure fitted on the vertical post, capable of sliding up and down along the vertical post. Each of the hauling ropes is respectively connected to the guiding structure, and each of the hauling ropes respectively goes through the guiding structure. One end of the hauling rope close to the guiding structure is connected with a handle. The hauling ropes are in a cyclic form. The hauling ropes can maintain a tightened state, and can be applied in different exercising modes.

Abstract: A method is provided for determining the efficacy of GPC3-targeting drug therapy for cancer in a patient before the start of GPC3-targeting drug therapy or for determining the continuation of GPC3-targeting drug therapy for a patient treated with GPC3-targeting therapy. The method includes determining the number of an immunocyte or an expression level of a molecule expressed on the immunocyte in a biological sample isolated from the patient before the start of GPC3-targeting drug therapy and/or the patient treated with the GPC3-targeting drug therapy, wherein when the number of the immunocyte or the expression level of the molecule expressed on the immunocyte is a predetermined value, the efficacy of the GPC3-targeting drug therapy is determined or the continuation of the GPC3-targeting drug therapy is determined. GPC3-targeting drugs and drug preparations for use according to the disclosed methods are also provided.

Abstract: Disclosed is a weight training device that can be transformed into a hand truck. The device includes a main frame, two first wheels, a second wheel, two first installing tubes, two second installing tubes and two operating parts, wherein the main frame is used for loading at least one heavy object. Each wheel is fitted on the main frame in a rotational manner, so that the main frame can be moved through the rolling of the wheels. Each of the first installing tubes are opposite each other and respectively extends upward. Each of the second installing tubes are opposite each other and respectively extend away from the main frame. Each of the operating parts are opposite each other in the lateral direction and are respectively and selectively configured on each of the first or each of the second installing tubes, so as to shift the operating mode of weight training.

Abstract: The present invention is directed to a chest pad that significantly reduces the occurrence of commotio cordis among athletes. The chest pad may be utilized as a stand-alone chest protector intended to provide coverage primarily for the upper chest wall and the cardiac area. The chest pad may also be implanted into or utilized in traditional chest protectors that provide full coverage of the user's torso. The chest pad of the present invention provides additional protection to the heart of the wearer such that impact in the heart area with a projectile is absorbed by the chest pad.

Abstract: A chest pad that significantly reduces the occurrence of commotio cordis among athletes is disclosed. The chest pad may be utilized as a stand-alone chest protector intended to provide coverage primarily for the upper chest wall and the cardiac area. The chest pad may also be implanted into or utilized in traditional chest protectors that provide full coverage of the user's torso. The chest pad provides additional protection to the heart of the wearer such that impact in the heart area with a projectile is absorbed by the chest pad.

Abstract: A flywheel exerciser having a hybrid resistance system includes: a body having a flywheel unit; a wind resistance system disposed on the flywheel unit; and a magnetic resistance system disposed on the flywheel unit. The wind resistance system is a conventional wind resistance which provides segmental adjustment, the present invention is additionally provided with a magnetic resistance system. When the resistance generated by the wind resistance system is insufficient or excessive, the resistance can be further finely increased or decreased by adjusting the magnetic resistance system to provide the resistance that best meets the user's needs.

Abstract: The present invention is directed to a leg guard that provides increased protection while also providing maximum articulation and increased freedom of movement for the user. More particularly, the leg guard includes a toe guard, a shin guard, a knee guard including an extended knee cap wrap, an extended knee guard, a thigh guard, a left hinge, and a right hinge. Through the use of an extended knee cap wrap and a hinged configuration, the leg guard provides additional protection for the knees of a catcher and allows catchers to freely and quickly move to or through different stances without having to re-position the pads of the leg guard. The hinged configuration provides enhanced mobility for the user by preventing the leg guard from shifting and rotating about the shin of the user and allowing the leg guard to remain static without axial rotation or vertical movement.

Abstract: An interactive sports management device combined with human physiological information and sports information includes a user module, an exercise module and a management module, wherein the user module is used to detect the physiological information of the user, and transmit the user identifier and the physiological information to the exerciser module. The exercise module is used to collect the sports information of the sports fitness equipment, and transmit the user identifier, the physiological information, the exerciser identifier and the sports information to the management module. The management module transmits the management information to the exerciser module. In this way, the sports information generated when the specific person uses the specific sports fitness equipment for exercise is combined with the human physiological information into the personalized information.

Abstract: Instructions for using sport fitness equipment combined with human physiological information and sports information are provided. The instruction of use is performed by using a sports management device. When a user uses the sport fitness machine to exercise, the sports management device can combine the physiological information of the user with the exercise information of the exercise state of the exercise machine, then provide the user or professional sports and fitness coach to view it any time, as a reference for the user to decide the following sport item or whether the intensity of exercise needs to be adjusted.

Abstract: An interactive sports management device combined with human physiological information and sports information includes a user module, an exercise module and a management module, wherein the user module is used to detect the physiological information of the user, and transmit the user identifier and the physiological information to the exerciser module. The exercise module is used to collect the sports information of the sports fitness equipment, and transmit the user identifier, the physiological information, the exerciser identifier and the sports information to the management module. The management module transmits the management information to the exerciser module. In this way, the sports information generated when the specific person uses the specific sports fitness equipment for exercise is combined with the human physiological information into the personalized information.

Abstract: A dual color belt includes a belt body of an elastic webbing with front and back surfaces thereof differently colored so that the front side and back side of the belt body can be selectively used, and a belt buckle having an upper guide groove and a lower guide groove defined in a base component thereof for guiding the front end of the belt body into the base component for enabling the front end of the belt body to be engaged by a clamping plate of the belt buckle. Thus, installation between the belt body and the base component of the belt buckle and replacement between the front side and the back side of the belt body are easy.

Abstract: A flywheel exerciser having a hybrid resistance system includes: a body having a flywheel unit; a wind resistance system disposed on the flywheel unit; and a magnetic resistance system disposed on the flywheel unit. The wind resistance system is a conventional wind resistance which provides segmental adjustment, the present invention is additionally provided with a magnetic resistance system. When the resistance generated by the wind resistance system is insufficient or excessive, the resistance can be further finely increased or decreased by adjusting the magnetic resistance system to provide the resistance that best meets the user's needs.

Abstract: The present invention discloses a method for determining the efficacy of GPC3-targeting drug therapy for cancer in a patient before the start of GPC3-targeting drug therapy or a patient or determining the continuation of GPC3-targeting drug therapy for a patient, including monitoring a concentration of free GPC3 in a biological sample isolated from the patient before the start of GPC3-targeting drug therapy and/or the patient treated with the GPC3-targeting drug therapy, wherein when the concentration of free GPC3 is a predetermined value, the efficacy of the GPC3-targeting drug therapy is determined or the continuation of the GPC3-targeting drug therapy is determined. The present invention also discloses a GPC3-targeting drug or a preparation which is to be further administered to a patient for which the efficacy of the GPC3-targeting drug therapy has been determined or the continuation of the GPC3-targeting drug therapy has been determined.

Abstract: A column-type combination climbing exercise machine mainly includes: the bottom end of a stand frame provided with a ground seat; a column is locked with the stand frame through a locking component; two sliding chutes are respectively disposed at the opposite left and right sides of the column; two sliding seats are correspondingly disposed in the two sliding chute, each sliding seat is adjacent to the top thereof, and a handle and a pedal are respectively disposed at the two ends of the bottom; a first linkage mechanism is connected with the two sliding seats to form a mutually opposite lift-fall and linkage action; a damper is assembled in the ground seat; two connectors are respectively disposed in the two sliding a seat; and a second linkage mechanism makes the damper and the two sliding seats in a linkage relationship.

Abstract: A column-type combination climbing exercise machine mainly includes: the bottom end of a stand frame provided with a ground seat; a column is locked with the stand frame through a locking component; two sliding chutes are respectively disposed at the opposite left and right sides of the column; two sliding seats are correspondingly disposed in the two sliding chute, each sliding seat is adjacent to the top thereof, and a handle and a pedal are respectively disposed at the two ends of the bottom; a first linkage mechanism is connected with the two sliding seats to form a mutually opposite lift-fall and linkage action; a damper is assembled in the ground seat; two connectors are respectively disposed in the two sliding a seat; and a second linkage mechanism makes the damper and the two sliding seats in a linkage relationship.

Abstract: A barbell hanger includes: a vertical tube with a ground end, a top end and a tube body portion; plural barbell positioning portions are arranged at the tube body portion; the connecting end of a transverse tube has a first locking tray lock-positioned with the tube body portion; the extending end of the horizontal tube has a second locking tray; a pull-up operating frame is horizontally disposed below the horizontal tube, including the cross bar as well as the mounting end locking plate and the extended end locking plate; the mounting end locking plate is assembled in the vertical rectangular tube, and a relative relation of the locking surface between the extended end locking plate and the second locking tray is level with each other; two corner reinforcing plates are respectively disposed at cross bars and corners connected with the mounting end locking plate and extended end locking plate.

Abstract: An auxiliary arm of a barbell hanger mainly includes: a mounting seat including a positive abutting surface, a lateral abutting surface and a back abutting surface, and the mounting seat has a mounting portion, the mounting portion is selectively combined and positioned in any positioning portion of the barbell hanger; a laterally curved bracket is laterally convexly provided at the lateral abutting surface, and the laterally curved bracket has a first section, a second section and a curved section, wherein the end of the second section is provided with a barbell receiving frame, and the barbell receiving frame has the relative relationship of a forward-backward offset distance and a lateral offset relative to the mounting seat; a bar avoidance space formed jointly by the first section, the second section and the curved section of the laterally curved bracket are defined by the concave space.

Abstract: A multifunctional exercise fitness assisting device includes a main structure placed on a supporting surface, the main structure having first and second end faces; at least one side of the main structure is formed with a receiving space for receiving various exercise fitness equipment, wherein at least one supporting frame is provided in one receiving space. The two inner edges are respectively disposed at the pad on the top surface of the main structure, and an included angle is respectively formed between the bottom surface of the two pads and the top surface of the main structure, the angle being adjustable so as to help the user to use different exercise fitness modes. At least one pad and the main structure are provided with a limiting device which can selectively limit one corresponding pad when the included angle is adjusted to a preset angle.

Abstract: The present invention is directed to a chest pad that significantly reduces the occurrence of commotio cordis among athletes. The chest pad may be utilized as a stand-alone chest protector intended to provide coverage primarily for the upper chest wall and the cardiac area. The chest pad may also be implanted into or utilized in traditional chest protectors that provide full coverage of the user's torso. The chest pad of the present invention provides additional protection to the heart of the wearer such that impact in the heart area with a projectile is absorbed by the chest pad.