Patents by Inventor Ya-Ching Changchien

Ya-Ching Changchien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070248669
    Abstract: The present invention relates to an oral sustained release formulation comprising a core, a medicinal layer containing vanlafaxine or a pharmaceutically acceptable salt of venlafaxine and a release-modulating layer containing a release-modulating agent. The present invention also relates to a method for preparing an oral sustained release formulation, and to a pharmaceutical composition containing the oral sustained release formulation prepared by the method.
    Type: Application
    Filed: April 25, 2006
    Publication date: October 25, 2007
    Inventors: Fang-Hsiung Hsiao, Ya-Ching Changchien
  • Patent number: 6726931
    Abstract: The present invention relates to a process for producing an oral sustained-release pharmaceutical composition of felodipine. The process includes mixing together felodipine with at least an ionic surfactant or hydrophilic polymer, and at least a release-controlling excipient. The pharmaceutical composition of felodipine produced by the process of the present invention possesses the enhanced dissolution rate of the insoluble drug of felodipine, whereas the sustained releasing profile and superior bioavailability of the produced pharmaceutical composition of felodipine are retained.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: April 27, 2004
    Assignee: Standard Chem. & Pharm. Co., Ltd.
    Inventors: Yea-Sheng Yang, Ya-Ching Changchien
  • Publication number: 20040052844
    Abstract: The invention relates to a time-controlled, sustained release, pharmaceutical composition containing water-soluble resins, comprising:
    Type: Application
    Filed: September 16, 2002
    Publication date: March 18, 2004
    Inventors: Fang-Hsiung Hsiao, Sung-Jen Chen, Chien-Chu Lin, Ya-Ching Changchien
  • Publication number: 20030190356
    Abstract: The present invention relates to a process for producing an oral sustained-release pharmaceutical composition of felodipine. The process includes mixing together felodipine with at least an ionic surfactant or hydrophilic polymer, and at least a release-controlling excipient. The pharmaceutical composition of felodipine produced by the process of the present invention possesses the enhanced dissolution rate of the insoluble drug of felodipine, whereas the sustained releasing profile and superior bioavailability of the produced pharmaceutical composition of felodipine are retained.
    Type: Application
    Filed: April 8, 2002
    Publication date: October 9, 2003
    Inventors: Yea-Sheng Yang, Ya-Ching Changchien
  • Patent number: 6346269
    Abstract: The present invention relates to a method for preparing an oral formulation containing acid-sensitive drugs, including at least the following step: spreading a solution or a suspension containing at least stabilizers, solvents and acid-sensitive drugs or its pharmaceutically acceptable salts onto a core made from one or more excipients, and then drying the core to make an active ingredient layer over the core. Also disclosed is the oral formulation made by this method.
    Type: Grant
    Filed: May 8, 2000
    Date of Patent: February 12, 2002
    Assignee: Standard Chem. & Pharm. Co., Ltd.
    Inventors: Fang-Hsiung Hsiao, Chien-Chu Lin, Ya-Ching Changchien