Patents by Inventor Ya Fang Liu

Ya Fang Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying MLK inhibitors for treatment of neurological conditions
    Patent number: 7544479
    Abstract: The present invention describes methods for identifying compounds that inhibit JNK and MLK kinase activity as drugs for treating a mammal susceptible to or having a neurological condition. This invention also discloses methods for preventing neuronal cell death and treating neurological conditions that involve neuronal cell death, particularly neurodegenerative diseases characterized by glutamine or kainate mediated toxicity, such as Huntington's disease and Alzheimer's disease.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: June 9, 2009
    Inventor: Ya Fang Liu
  • JNK inhibitors for the treatment of neurological disorders
    Patent number: 7452686
    Abstract: The present invention describes methods for identifying compounds that inhibit JNK and MLK kinase activity as drugs for treating a mammal susceptible to or having a neurological condition. This invention also discloses methods for preventing neuronal cell death and treating neurological conditions that involve neuronal cell death, particularly neurodegenerative diseases characterized by glutamine or kainate mediated toxicity, such as Huntington's disease and Alzheimer's disease.
    Type: Grant
    Filed: January 9, 2002
    Date of Patent: November 18, 2008
    Inventor: Ya Fang Liu
  • Method for identifying JNK and MLK inhibitors for treatment of neurological conditions
    Patent number: 7264942
    Abstract: The present invention describes methods for identifying compounds that inhibit JNK and MLK kinase activity as drugs for treating a mammal susceptible to or having a neurological condition. This invention also discloses methods for preventing neuronal cell death and treating neurological conditions that involve neuronal cell death, particularly neurodegenerative diseases characterized by glutamine or kainate mediated toxicity, such as Huntington's disease and Alzheimer's disease.
    Type: Grant
    Filed: February 5, 2003
    Date of Patent: September 4, 2007
    Inventor: Ya Fang Liu
  • Method for identifying MLK inhibitors for the treatment of neurological conditions
    Patent number: 6811992
    Abstract: The present invention describes methods for identifying compounds that inhibit JNK and MLK kinase activity as drugs for treating a mammal susceptible to or having a neurological condition. This invention also discloses methods for preventing neuronal cell death and treating neurological conditions that involve neuronal cell death, particularly neurodegenerative diseases characterized by glutamine or kainate mediated toxicity, such as Huntington's disease and Alzheimer's disease.
    Type: Grant
    Filed: September 17, 1998
    Date of Patent: November 2, 2004
    Inventor: Ya Fang Liu
  • Method for identifying JNK and MLK inhibitors for treatment of neurological conditions
    Publication number: 20030148395
    Abstract: The present invention describes methods for identifying compounds that inhibit JNK and MLK kinase activity as drugs for treating a mammal susceptible to or having a neurological condition. This invention also discloses methods for preventing neuronal cell death and treating neurological conditions that involve neuronal cell death, particularly neurodegenerative diseases characterized by glutamine or kainate mediated toxicity, such as Huntington's disease and Alzheimer's disease.
    Type: Application
    Filed: February 5, 2003
    Publication date: August 7, 2003
    Inventor: Ya Fang Liu
  • JNK inhibitors for the treatment of neurological disorders
    Publication number: 20020058245
    Abstract: The present invention describes methods for identifying compounds that inhibit JNK and MLK kinase activity as drugs for treating a mammal susceptible to or having a neurological condition. This invention also discloses methods for preventing neuronal cell death and treating neurological conditions that involve neuronal cell death, particularly neurodegenerative diseases characterized by glutamine or kainate mediated toxicity, such as Huntington's disease and Alzheimer's disease.
    Type: Application
    Filed: January 9, 2002
    Publication date: May 16, 2002
    Inventor: Ya Fang Liu
  • MLK inhibitors for the treatment of neurological disorders
    Publication number: 20020006606
    Abstract: The present invention describes methods for identifying compounds that inhibit JNK and MLK kinase activity as drugs for treating a mammal susceptible to or having a neurological condition. This invention also discloses methods for preventing neuronal cell death and treating neurological conditions that involve neuronal cell death, particularly neurodegenerative diseases characterized by glutamine or kainate mediated toxicity, such as Huntington's disease and Alzheimer's disease.
    Type: Application
    Filed: June 21, 2001
    Publication date: January 17, 2002
    Inventor: Ya Fang Liu